{"id":42088,"date":"2021-05-20T10:00:45","date_gmt":"2021-05-20T01:00:45","guid":{"rendered":"https:\/\/www.nahls.co.jp\/eijingukea\/?p=42088"},"modified":"2022-07-07T21:06:05","modified_gmt":"2022-07-07T12:06:05","slug":"carbamylation","status":"publish","type":"post","link":"https:\/\/www.nahls.co.jp\/eijingukea\/editorial_news\/carbamylation\/","title":{"rendered":"\u6ce8\u76ee\u306e\u65b0\u767a\u898b\uff01\u30b3\u30e9\u30fc\u30b2\u30f3\u306e\u300c\u30ab\u30eb\u30d0\u30df\u30eb\u5316\u300d\u306f\u9854\u305f\u308b\u307f\u306e\u539f\u56e0"},"content":{"rendered":"
\n

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\n

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\"\u5e74\u4ee3\u5225\u808c\u60a9\u307f\u306e\u56f3\"<\/p>\n

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\uff0a100\uff05\u5929\u7136\u6d77\u6c34\u9b5a\u304b\u3089\u62bd\u51fa\u3057\u305f\u30de\u30ea\u30f3\u30b3\u30e9\u30fc\u30b2\u30f3\u306e\u79d8\u5bc6<\/a><\/p>\n

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\n

3\uff0e\u65b0\u305f\u306a\u30a8\u30a4\u30b8\u30f3\u30b0\u8981\u56e0\u306e\u300c\u30ab\u30eb\u30d0\u30df\u30eb\u5316\u300d\u3068\u306f\uff1f<\/h2>\n

\"\u30ab\u30eb\u30d0\u30df\u30eb\u5316\u304c\u3069\u306e\u3088\u3046\u306a\u3082\u306e\u304b\u3092\u8003\u3048\u308b\u5973\u6027\"<\/p>\n

\u30ab\u30eb\u30d0\u30df\u30eb\u5316\u306b\u3064\u3044\u3066\u306f\u3001\u3082\u3068\u3082\u3068\u30ea\u30a6\u30de\u30c1\u3084\u95a2\u7bc0\u708e\u3001\u7cd6\u5c3f\u75c5\u3001\u6162\u6027\u814e\u75be\u60a3\u306a\u3069\u3001\u75be\u75c5\u306e\u5206\u91ce\u3067\u7814\u7a76\u304c\u9032\u3093\u3067\u3044\u307e\u3057\u305f\u3002<\/p>\n

\u305f\u3068\u3048\u3070\u3001\u30ab\u30eb\u30d0\u30df\u30eb\u5316\u304c\u8840\u7ba1\u77f3\u7070\u5316\u3092\u5897\u60aa\u3055\u305b\u308b\u3053\u3068\u304c\u660e\u3089\u304b\u306b\u306a\u3063\u3066\u3044\u307e\u3059\u3002\u305d\u306e\u305f\u3081\u3001\u30ab\u30eb\u30d0\u30df\u30eb\u5316\u3092\u6291\u5236\u3059\u308b\u4ecb\u5165\u65b9\u6cd5\u3092\u78ba\u7acb\u3057\u3001\u6cbb\u7642\u306b\u4f7f\u3048\u308b\u7814\u7a76\u304c\u9032\u3093\u3067\u3044\u307e\u3059\u3002<\/p>\n

\n

\uff1c\u53c2\u8003\u8a18\u4e8b\uff1e<\/b>
\n\uff0a
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\u3053\u308c\u3092\u300c\u30ab\u30eb\u30d0\u30df\u30eb\u5316\u300d\u3068\u547c\u3093\u3067\u3044\u307e\u3059\u3002<\/p>\n

\u9178\u5316\u3084\u7cd6\u5316\u3067\u306f\u30b3\u30e9\u30fc\u30b2\u30f3\u304c\u56fa\u304f\u306a\u308b\u306e\u3068\u5bfe\u7167\u7684\u3067\u3059\u3002<\/p>\n

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\u3057\u304b\u3057\u300120\u6b73\u4ee3\u306b\u306a\u3063\u3066\u4ee3\u8b1d\u304c\u4f4e\u4e0b\u3057\u3066\u304f\u308b\u3068\u3001\u5c3f\u7d20\u306e\u5206\u89e3\u7269\u306b\u3088\u308a\u30ab\u30eb\u30d0\u30df\u30eb\u5316\u3057\u305f\u30b3\u30e9\u30fc\u30b2\u30f3\u304c\u84c4\u7a4d\u3055\u308c\u3066\u3001\u30b3\u30e9\u30fc\u30b2\u30f3\u306e\u640d\u50b7\u3084\u52a3\u5316\u3092\u5f15\u304d\u8d77\u3053\u3057\u307e\u3059\u3002<\/p>\n

\u3053\u306e\u3053\u3068\u304c\u7406\u7531\u3067\u3001\u304a\u808c\u304c\u67d4\u3089\u304b\u304f\u306a\u3063\u3066\u5f3e\u529b\u304c\u306a\u304f\u306a\u308a\u3001\u304a\u9854\u306e\u305f\u308b\u307f\u3001\u30b7\u30ef\u306b\u3064\u306a\u304c\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n

\n

\uff1c\u53c2\u8003\uff1e<\/b><\/p>\n

\u30fbCamille N, et al. Carbamylation and glycation compete for collagen molecular aging in vivo. Sci Rep 9(1): 18291, 2019<\/a><\/p>\n

\u30fb\u86cb\u767d\u30ab\u30eb\u30d0\u30df\u30eb\u5316\u306f\u8840\u7ba1\u77f3\u7070\u5316\u3092\u60aa\u5316\u3055\u305b\u308b\uff08Mori D, et al. Protein carbamylation exacerbates vascular calcification. Kidney Int. 2018 Apr 28. PMID: 29716796\uff09.\u5927\u962a\u5927\u5b66\u814e\u81d3\u5185\u79d1\u30db\u30fc\u30e0\u30da\u30fc\u30b8<\/a><\/p>\n

\u30fb\u9ed2\u5ddd\u771f\u5948\u7d75. \u81e8\u5e8a\u30ea\u30a6\u30de\u30c1\u533b\u306e\u305f\u3081\u306e\u57fa\u790e\u8b1b\u5ea7\u3000\u30ea\u30a6\u30de\u30c1\u30fb\u81a0\u539f\u75c5\u3068\u7ffb\u8a33\u5f8c\u4fee\u98fe\u7570\u5e38.\u3000 \u81e8\u5e8a\u30ea\u30a6\u30de\u30c127: 313-317, 2015.<\/a><\/p>\n

\u30fb\u682a\u5f0f\u4f1a\u793e\u30c9\u30af\u30bf\u30fc\u30b7\u30fc\u30e9\u30dc\u30d7\u30ec\u30b9\u30ea\u30ea\u30fc\u30b9. 2020\/8\/17<\/a><\/p>\n<\/div>\n


\n

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\n

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\u307b\u304b\u306b\u3082\u4e9c\u925b\u3084\u9285\u3001\u9244\u3082\u30b3\u30e9\u30fc\u30b2\u30f3\u3092\u3064\u304f\u308b\u305f\u3081\u306b\u5927\u5207\u306a\u30df\u30cd\u30e9\u30eb\u3067\u3059\u3002<\/p>\n

2\uff09\u4f53\u6e29\u30a2\u30c3\u30d7\u3084\u514d\u75ab\u30a2\u30c3\u30d7\u3082\u826f\u3044\u65b9\u6cd5<\/h3>\n

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\uff1c\u53c2\u8003\u8a18\u4e8b\uff1e<\/p>\n

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3\uff09\u30b9\u30c8\u30ec\u30b9\u30aa\u30d5\u3067\u30ab\u30eb\u30d0\u30df\u30eb\u5316\u3092\u4e88\u9632<\/h3>\n

\u30b9\u30c8\u30ec\u30b9\u3082\u4ee3\u8b1d\u306b\u60aa\u5f71\u97ff\u3092\u53ca\u307c\u3057\u3001\u30a8\u30a4\u30b8\u30f3\u30b0\u3092\u9032\u3081\u307e\u3059\u3002<\/p>\n

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\u307e\u305a\u306f\u3001\u8cea\u306e\u9ad8\u3044\u7761\u7720<\/a>\u3092\u3068\u308b\u3053\u3068\u304c\u5927\u5207\u3067\u3059\u3002<\/p>\n

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\u3055\u3089\u306b\u3001\u30c0\u30de\u30b9\u30af\u30ed\u30fc\u30ba<\/a>\u306e\u9999\u308a\u3092\u306f\u3058\u3081\u3001\u30a2\u30ed\u30de\u30c6\u30e9\u30d4\u30fc<\/a>\u3082\u30b9\u30c8\u30ec\u30b9\u89e3\u6d88\u306b\u5f79\u7acb\u3061\u307e\u3059\u3002<\/p>\n

\uff1c\u53c2\u8003\u8a18\u4e8b\uff1e<\/p>\n

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4\uff09\u55ab\u7159\u7fd2\u6163\u304c\u306a\u3051\u308c\u3070\u30ab\u30eb\u30d0\u30df\u30eb\u5316\u306f\u9045\u3089\u305b\u308b<\/h3>\n

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\uff1c\u53c2\u8003\u8a18\u4e8b\uff1e<\/p>\n

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5\uff09\u5927\u6c17\u6c5a\u67d3\u5bfe\u7b56\u3082\u5fc5\u8981<\/h3>\n

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\u307e\u305f\u3001\u5927\u6c17\u6c5a\u67d3\u304c\u9032\u3093\u3067\u3044\u308b\u5730\u57df\u3078\u884c\u304b\u306a\u3044\u3088\u3046\u306b\u3059\u308b\u3053\u3068\u3082\u30ab\u30eb\u30d0\u30df\u30eb\u5316\u306e\u4e88\u9632\u306b\u3064\u306a\u304c\u308a\u307e\u3059\u3002<\/p>\n


\n

6\uff0e\u30ab\u30eb\u30d0\u30df\u30eb\u5316\u3092\u4e88\u9632\u3059\u308b\u7f8e\u5bb9\u6210\u5206\u300c\u30b7\u30a4\u30bf\u30b1\u30a8\u30ad\u30b9\u300d<\/h2>\n

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\"\u30b7\u30a4\u30bf\u30b1\u30a8\u30ad\u30b9\u306e\u30ab\u30eb\u30d0\u30df\u30eb\u5316\u9632\u6b62\u52b9\u679c\u306e\u30b0\u30e9\u30d5\"<\/p>\n

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\n

7\uff0e\u7de8\u96c6\u5f8c\u8a18<\/h2>\n

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\n
\n

\u8457\u8005\u30fb\u7de8\u96c6\u8005\u30fb\u6821\u6b63\u8005\u60c5\u5831<\/h2>\n<\/div>\n
\n

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\u533b\u5b66\u51fa\u7248\u793e\u3001\u533b\u5b66\u7cfb\u5e83\u544a\u4ee3\u7406\u5e97\u306b\u3066\u7de8\u96c6\u30fb\u30e9\u30a4\u30bf\u30fc\u3068\u3057\u3066\u3001\u533b\u5e2b\u5411\u3051\u3001\u60a3\u8005\u5411\u3051\u306e\u60c5\u5831\u63d0\u4f9b\u8cc7\u6750\u3084\u66f8\u7c4d\u7b49\u306e\u8a18\u4e8b\u306e\u7de8\u96c6\u30fb\u57f7\u7b46\u3084\u3001\u56fd\u5185\u30fb\u6d77\u5916\u533b\u5b66\u4f1a\u53d6\u6750\u30fb\u8a18\u4e8b\u57f7\u7b46\u3092\u884c\u3046\u3002<\/p>\n

\"\u8457\u8005\u60c5\u5831\u3000\u682a\u5f0f\u4f1a\u793e\u30c7\u30a3\u30fc\u30d7\u30a4\u30f3\u30d1\u30af\u30c8\u3000\u5bcc\u672c\u5145\u662d\"
\n\uff08\u7de8\u96c6\u30fb\u6821\u6b63\uff1a\u682a\u5f0f\u4f1a\u793e\u30c7\u30a3\u30fc\u30d7\u30a4\u30f3\u30d1\u30af\u30c8\u3000\u4ee3\u8868\u53d6\u7de0\u5f79\u3000\u5bcc\u672c\u5145\u662d\uff09<\/p>\n

\u30ca\u30fc\u30eb\u30b9\u30a8\u30a4\u30b8\u30f3\u30b0\u30b1\u30a2\u30a2\u30ab\u30c7\u30df\u30fc\u7de8\u96c6\u9577<\/a><\/p>\n

\u4eac\u90fd\u5927\u5b66\u8fb2\u5b66\u90e8\u3092\u5352\u696d\u5f8c\u3001\u88fd\u85ac\u4f01\u696d\u306b7\u5e74\u9593\u52e4\u52d9\u306e\u5f8c\u3001\u533b\u5b66\u51fa\u7248\u793e\u3001\u533b\u5b66\u7cfb\u5e83\u544a\u4ee3\u7406\u5e97\u52e4\u52d9\u306e\u5f8c\u3001\u73fe\u8077\u306b\u81f3\u308b\u3002<\/p>\n

\u533b\u85ac\u54c1\u306e\u958b\u767a\u652f\u63f4\u696d\u52d9\u3001\u533b\u5b66\u7cfb\u5b66\u4f1a\u306e\u53d6\u6750\u3084\u8a18\u4e8b\u57f7\u7b46\u3001\u533b\u85ac\u54c1\u30de\u30fc\u30b1\u30c6\u30a3\u30f3\u30b0\u95a2\u9023\u306e\u30bb\u30df\u30ca\u30fc\u8b1b\u5e2b\u306a\u3069\u3092\u884c\u3046\u3002<\/p>\n

\u6587\u90e8\u79d1\u5b66\u7701\u5f8c\u63f4\u65e5\u672c\u5316\u7ca7\u54c1\u691c\u5b9a1\u7d1a<\/a>\u3002<\/p>\n

\u4e00\u822c\u793e\u56e3\u6cd5\u4eba\u5316\u7ca7\u54c1\u6210\u5206\u691c\u5b9a\u5354\u4f1a\u8a8d\u5b9a\u5316\u7ca7\u54c1\u6210\u5206\u4e0a\u7d1a\u30b9\u30da\u30b7\u30e3\u30ea\u30b9\u30c8<\/a><\/p>\n

\u8457\u4f5c\uff08\u5171\u8457\uff09<\/p>\n

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\n
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\u5f53\u793e\u30b9\u30bf\u30c3\u30d5\u306e\u672c\u696d\u306f\u3001\u533b\u5b66\u30fb\u85ac\u5b66\u95a2\u9023\u306e\u4e8b\u696d\u306e\u305f\u3081\u3001\u65e5\u3005\u3001\u533b\u5b66\u8ad6\u6587\u3084\u533b\u5b66\u4f1a\u306e\u767a\u8868\u306a\u3069\u306e\u6700\u65b0\u60c5\u5831\u306b\u89e6\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n

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\u25b6\u30ca\u30fc\u30eb\u30b9\u30c1\u30e3\u30f3\u30cd\u30eb\u3092\u307f\u3066\u52d5\u753b\u3067\u30a8\u30a4\u30b8\u30f3\u30b0\u30b1\u30a2\u3092\u5b66\u307c\u3046\uff01<\/a><\/p>\n\n\n\n \t

\u95a2\u9023\u8a18\u4e8b<\/div>\n\t \t\t\n\t
\n\t \n\t
\n\t \t\t

\n\t \u30b3\u30e9\u30fc\u30b2\u30f3\u3092\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u3067\u6442\u308c\u3070\u52b9\u679c\u7684\u3002\u30a8\u30d3\u30c7\u30f3\u30b9\u3092\u77e5\u3063\u3066\u7f8e\u808c\u306b\uff01\t <\/a><\/h4>\n\t \t

\u7d9a\u304d\u3092\u8aad\u3080<\/a><\/p>\n\t <\/div>\n\t <\/div>\n\t \n\t \t\t\n\t

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\n\t \u2163\u578b\u30b3\u30e9\u30fc\u30b2\u30f3\u306e\u7279\u5fb4\u3068\u305d\u308c\u3092\u5b88\u308b\u30d7\u30ea\u30f3\u30bb\u30b9\u30b1\u30a2\t <\/a><\/h4>\n\t \t

\u7d9a\u304d\u3092\u8aad\u3080<\/a><\/p>\n\t <\/div>\n\t <\/div>\n\t \n\t \t\t\n\t

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\u7d9a\u304d\u3092\u8aad\u3080<\/a><\/p>\n\t <\/div>\n\t <\/div>\n\t \n\t \t\t\n\t

\n\t \n\t
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\n\t \u30b3\u30e9\u30fc\u30b2\u30f3\u306e\u6b63\u3057\u3044\u6442\u308a\u65b9\u3092\u77e5\u3063\u3066\u7f8e\u808c\u3068\u30a2\u30f3\u30c1\u30a8\u30a4\u30b8\u30f3\u30b0\t <\/a><\/h4>\n\t \t

\u7d9a\u304d\u3092\u8aad\u3080<\/a><\/p>\n\t <\/div>\n\t <\/div>\n\t \n\t \t\t\n\t

\n\t \n\t
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\u7d9a\u304d\u3092\u8aad\u3080<\/a><\/p>\n\t <\/div>\n\t <\/div>\n\t \n\t \n

nahls\u30a8\u30a4\u30b8\u30f3\u30b0\u30b1\u30a2\u30a2\u30ab\u30c7\u30df\u30fc<\/span>\u3092\u8a2a\u308c\u3066\u3044\u305f\u3060\u304d\u3001\u3042\u308a\u304c\u3068\u3046\u3054\u3056\u3044\u307e\u3059\u3002<\/br>\r\n<\/br>\r\nnahls\u30a8\u30a4\u30b8\u30f3\u30b0\u30b1\u30a2\u30a2\u30ab\u30c7\u30df\u30fc<\/span>\u3067\u306f\u5553\u767a\u7684\u306a\u5185\u5bb9\u304c\u4e2d\u5fc3\u3067\u3059\u304c\u3001<\/br>\r\n\u30ca\u30fc\u30eb\u30b9\u30b3\u30e0<\/span>\u3067\u306f\u3001\u30ca\u30fc\u30eb\u30b9\u30d6\u30e9\u30f3\u30c9\u306e\u88fd\u54c1\u60c5\u5831\u3060\u3051\u3067\u306a\u304f\u3001<\/br>\r\n\u304a\u5ba2\u69d8\u306b\u3054\u53c2\u52a0\u3044\u305f\u3060\u3044\u305f\u5ea7\u8ac7\u4f1a\u3084<\/br>\r\n\u30b9\u30ad\u30f3\u30b1\u30a2\u30fb\u30a8\u30a4\u30b8\u30f3\u30b0\u30b1\u30a2\u306e\u304a\u5f79\u306b\u7acb\u3064\u30b3\u30f3\u30c6\u30f3\u30c4\u304c\u6e80\u8f09\u3067\u3059\u3002<\/br>\r\n<\/br>\r\n\u304d\u3063\u3068\u3001\u3042\u306a\u305f\u306b\u3068\u3063\u3066\u3001\u5fc5\u8981\u306a\u60c5\u5831\u304c\u898b\u3064\u304b\u308b\u3068\u601d\u3044\u307e\u3059\u3002<\/br>\r\n\u4e0b\u8a18\u304b\u3089\u3001\u3069\u3046\u305e\u3002<\/br>\r\n<\/br>\r\n\u30ca\u30fc\u30eb\u30b9\u30b2\u30f3\u914d\u5408\u30a8\u30a4\u30b8\u30f3\u30b0\u30b1\u30a2\u5316\u7ca7\u54c1\u306a\u3089\u300c\u30ca\u30fc\u30eb\u30b9\u30b3\u30e0\u300d<\/a><\/span>\r\n<\/p>\r\n","protected":false},"excerpt":{"rendered":"

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