{"id":66569,"date":"2026-01-22T20:34:52","date_gmt":"2026-01-22T11:34:52","guid":{"rendered":"https:\/\/www.nahls.co.jp\/eijingukea\/?p=66569"},"modified":"2026-01-22T21:03:55","modified_gmt":"2026-01-22T12:03:55","slug":"nahls-pure_ank","status":"publish","type":"post","link":"https:\/\/www.nahls.co.jp\/eijingukea\/evidences\/hiroba\/nahls-pure_ank\/","title":{"rendered":"\u300c\u7d20\u808c\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u300d\u3068\u3044\u3046\u65b0\u767a\u60f3\u306e\u30b9\u30ad\u30f3\u30b1\u30a2\u30a2\u30a4\u30c6\u30e0\u300e\u30ca\u30fc\u30eb\u30b9\u30d4\u30e5\u30a2\u300f by\u30a2\u30f3\u30af\u2606"},"content":{"rendered":"
\n

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 <\/p>\n

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4\uff0e\u30ca\u30fc\u30eb\u30b9\u30a8\u30a4\u30b8\u30f3\u30b0\u30b1\u30a2\u30a2\u30ab\u30c7\u30df\u30fc\u7de8\u96c6\u90e8\u30b3\u30e1\u30f3\u30c8<\/h2>\n

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 <\/p>\n

\uff1c\u53c2\u7167\u8ad6\u6587\uff1e<\/h2>\n
\r\n\u30101\u3011Bissett DL, Oblong JE, Berge CA. Niacinamide: A B vitamin that improves aging facial skin appearance. Dermatologic Surgery. 2005;31(7 Pt 2):860\u2013865.<\/cite><\/a>
\r\n\r\nPMID: 16029679\uff5cDOI: 10.1111\/j.1524-4725.2005.31726
\r\n\r\n\u65e5\u672c\u8a9e\u8981\u65e8\uff1a<\/strong>\u672c\u81e8\u5e8a\u7814\u7a76\u3067\u306f\u30ca\u30a4\u30a2\u30b7\u30f3\u30a2\u30df\u30c9\u5916\u7528\u306b\u3088\u308a\u5c0f\u3058\u308f\u3084\u8272\u30e0\u30e9\u3001\u30d0\u30ea\u30a2\u6a5f\u80fd\u306e\u6539\u5584\u304c\u793a\u3055\u308c\u305f\u3002\u30ca\u30fc\u30eb\u30b9\u30d4\u30e5\u30a2\u306b\u914d\u5408\u3055\u308c\u308b\u30ca\u30a4\u30a2\u30b7\u30f3\u30a2\u30df\u30c9\u304c\u3001\u808c\u306e\u57fa\u76e4\u3067\u3042\u308b\u30d0\u30ea\u30a2\u6a5f\u80fd\u3092\u6574\u3048\u3001\u6f64\u3044\u3068\u6ed1\u3089\u304b\u3055\u306e\u6301\u7d9a\u306b\u5bc4\u4e0e\u3059\u308b\u79d1\u5b66\u7684\u6839\u62e0\u3002
\r\n\r\n\u30102\u3011Pullar JM, Carr AC, Vissers MCM. The Roles of Vitamin C in Skin Health. Nutrients. 2017;9(8):866.<\/a><\/cite>
\r\n\r\nPMID: 28805671\uff5cDOI: 10.3390\/nu9080866
\r\n\r\n\u65e5\u672c\u8a9e\u8981\u65e8\uff1a<\/strong>\u30d3\u30bf\u30df\u30f3C\u306f\u30b3\u30e9\u30fc\u30b2\u30f3\u5408\u6210\u4fc3\u9032\u3001\u6297\u9178\u5316\u4f5c\u7528\u3001\u30e1\u30e9\u30cb\u30f3\u751f\u6210\u6291\u5236\u306a\u3069\u591a\u9762\u7684\u306b\u76ae\u819a\u306e\u5065\u5eb7\u306b\u95a2\u4e0e\u3059\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u308b\u3002\u672c\u8ad6\u6587\u306f\u3001\u30ca\u30fc\u30eb\u30b9\u30d4\u30e5\u30a2\u306b\u542b\u307e\u308c\u308b\u30d3\u30bf\u30df\u30f3C\u8a98\u5c0e\u4f53\u304c\u3001\u808c\u306e\u30cf\u30ea\u3084\u900f\u660e\u611f\u3092\u652f\u3048\u308b\u30a8\u30a4\u30b8\u30f3\u30b0\u30b1\u30a2\u8a2d\u8a08\u306e\u79d1\u5b66\u7684\u80cc\u666f\u3002
\r\n\r\n\u30103\u3011Rawlings AV, Harding CR. Moisturization and skin barrier function. Dermatologic Therapy. 2004;17(Suppl 1):43\u201348.<\/a><\/cite>
\r\n\r\nPMID: 14728698\uff5cDOI: 10.1111\/j.1396-0296.2004.04s1005.x
\r\n\r\n\u65e5\u672c\u8a9e\u8981\u65e8\uff1a<\/strong>\u89d2\u8cea\u5c64\u306e\u6c34\u5206\u4fdd\u6301\u3068\u76ae\u819a\u30d0\u30ea\u30a2\u6a5f\u80fd\u306e\u5bc6\u63a5\u306a\u95a2\u4fc2\u306b\u3064\u3044\u3066\u4f53\u7cfb\u7684\u306b\u89e3\u8aac\u3057\u305f\u7dcf\u8aac\u3067\u3042\u308b\u3002\u30ca\u30fc\u30eb\u30b9\u30d4\u30e5\u30a2\u306e\u9ad8\u4fdd\u6e7f\u30fb\u30d0\u30ea\u30a2\u30b5\u30dd\u30fc\u30c8\u51e6\u65b9\u304c\u3001\u6f64\u3044\u3092\u4fdd\u3061\u3084\u3059\u3044\u808c\u74b0\u5883\u3092\u6574\u3048\u308b\u3053\u3068\u3092\u88cf\u4ed8\u3051\u308b\u57fa\u790e\u6587\u732e\u3002
\r\n\r\n\u30104\u3011Draelos ZD. The science behind skin care: Moisturizers. Journal of Cosmetic Dermatology. 2018;17(2):138\u2013144.<\/a><\/cite>
\r\n\r\nPMID: 29319217\uff5cDOI: 10.1111\/jocd.12490
\r\n\r\n\u65e5\u672c\u8a9e\u8981\u65e8\uff1a<\/strong>\u4fdd\u6e7f\u5264\uff08\u5316\u7ca7\u6c34\u306a\u3069\uff09\u306e\u4f5c\u7528\u6a5f\u5e8f\u3092\u6574\u7406\u3057\u305f\u30ec\u30d3\u30e5\u30fc\u3067\u3042\u308a\u3001\u30d2\u30e5\u30fc\u30e1\u30af\u30bf\u30f3\u30c8\u3084\u30a8\u30e2\u30ea\u30a8\u30f3\u30c8\u306e\u5f79\u5272\u3092\u89e3\u8aac\u3057\u3066\u3044\u308b\u3002\u4f4e\u523a\u6fc0\u30fb\u6bce\u65e5\u4f7f\u3048\u308b\u51e6\u65b9\u8a2d\u8a08\u306e\u30ca\u30fc\u30eb\u30b9\u30d4\u30e5\u30a2\u304c\u3001\u7d99\u7d9a\u4f7f\u7528\u306b\u3088\u308b\u808c\u30b3\u30f3\u30c7\u30a3\u30b7\u30e7\u30f3\u7dad\u6301\u306b\u9069\u3057\u3066\u3044\u308b\u3053\u3068\u3092\u793a\u3059\u7406\u8ad6\u7684\u6839\u62e0\u3002
\r\n\r\n\u30105\u3011Verdier-S\u00e9vrain S, Bont\u00e9 F. Skin hydration: a review on its molecular mechanisms. Journal of Cosmetic Dermatology. 2007;6(2):75\u201382.<\/a><\/cite>
\r\n\r\nPMID: 17524122\uff5cDOI: 10.1111\/j.1473-2165.2007.00300.x
\r\n\r\n\u65e5\u672c\u8a9e\u8981\u65e8\uff1a<\/strong>\u76ae\u819a\u306e\u6f64\u3044\u306f\u3001\u5929\u7136\u4fdd\u6e7f\u56e0\u5b50\uff08NMF\uff09\u3068\u7d30\u80de\u9593\u8102\u8cea\u306e\u76f8\u4e92\u4f5c\u7528\u306b\u3088\u3063\u3066\u7dad\u6301\u3055\u308c\u308b\u3053\u3068\u3092\u5206\u5b50\u30ec\u30d9\u30eb\u3067\u89e3\u8aac\u3057\u305f\u7dcf\u8aac\u3067\u3042\u308b\u3002\u30ca\u30fc\u30eb\u30b9\u30d4\u30e5\u30a2\u306e\u300c\u6f64\u3044\u304c\u7d9a\u304f\u300d\u3068\u3044\u3046\u4f7f\u7528\u611f\u304c\u3001\u76ae\u819a\u751f\u7406\u5b66\u7684\u306b\u59a5\u5f53\u3067\u3042\u308b\u3053\u3068\u3092\u8aac\u660e\u3059\u308b\u6839\u62e0\u3002
\r\n\r\n\u30106\u3011Elias PM, Steinhoff M. Skin barrier function. Current Allergy and Asthma Reports. 2008;8(4):299\u2013305.<\/a><\/cite>
\r\n\r\nPMID: 18606081\uff5cDOI: 10.1007\/s11882-008-0048-7
\r\n\r\n\u65e5\u672c\u8a9e\u8981\u65e8\uff1a<\/strong>\u76ae\u819a\u30d0\u30ea\u30a2\u6a5f\u80fd\u3068\u514d\u75ab\u5fdc\u7b54\u306e\u95a2\u4fc2\u3092\u5305\u62ec\u7684\u306b\u89e3\u8aac\u3057\u305f\u30ec\u30d3\u30e5\u30fc\u3002\u30d0\u30ea\u30a2\u6a5f\u80fd\u3092\u6574\u3048\u308b\u3053\u3068\u304c\u523a\u6fc0\u306b\u5f37\u3044\u808c\u306b\u3064\u306a\u304c\u308a\u3001\u30ca\u30fc\u30eb\u30b9\u30d4\u30e5\u30a2\u306e\u30d0\u30ea\u30a2\u91cd\u8996\u8a2d\u8a08\u304c\u654f\u611f\u306b\u306a\u308a\u3084\u3059\u3044\u808c\u306e\u571f\u53f0\u30b1\u30a2\u3068\u3057\u3066\u6709\u52b9\u3067\u3042\u308b\u3053\u3068\u3092\u793a\u5506\u3059\u308b\u3002
\r\n\r\n\u30107\u3011\u6e6f\u6d45\uff08\u5c0f\u5cf6\uff09\u660e\u5b50, \u6797\u7db8\u5b50, \u97d3\u7acb\u53cb, \u6e21\u8fba\u6587\u592a, \u5e73\u7af9\u6f64. \u03b3-\u30b0\u30eb\u30bf\u30df\u30eb\u30c8\u30e9\u30f3\u30b9\u30d7\u30c1\u30c0\u30fc\u30bc\uff08GGT\uff09\u963b\u5bb3\u5264\u306b\u3088\u308b\u30b3\u30e9\u30fc\u30b2\u30f3\u304a\u3088\u3073\u30a8\u30e9\u30b9\u30c1\u30f3\u7523\u751f\u80fd\u306e\u4ea2\u9032\u52b9\u679c\u3068\u305d\u306e\u30e1\u30ab\u30cb\u30ba\u30e0. \u65e5\u672c\u9999\u7ca7\u54c1\u5b66\u4f1a\u8a8c. 2012;36(2):93\u2013100.<\/cite><\/a>
\r\n\r\n\u65e5\u672c\u8a9e\u8981\u65e8\uff1a<\/strong>\u672c\u7814\u7a76\u306f\u3001\u30ca\u30fc\u30eb\u30b9\u30b2\u30f3\u00ae\u306e\u57fa\u3068\u306a\u308b\u03b3-\u30b0\u30eb\u30bf\u30df\u30eb\u30c8\u30e9\u30f3\u30b9\u30da\u30d7\u30c1\u30c0\u30fc\u30bc\uff08GGT\uff09\u963b\u5bb3\u5264\u304c\u3001\u30d2\u30c8\u76ae\u819a\u7dda\u7dad\u82bd\u7d30\u80de\u306b\u4f5c\u7528\u3057\u3066\u30b3\u30e9\u30fc\u30b2\u30f3\u304a\u3088\u3073\u30a8\u30e9\u30b9\u30c1\u30f3\u306e\u7523\u751f\u3092\u4fc3\u9032\u3059\u308b\u6a5f\u5e8f\u3092\u5206\u5b50\u30ec\u30d9\u30eb\u3067\u89e3\u6790\u3057\u305f\u3082\u306e\u3067\u3042\u308b\u3002\u5b9f\u9a13\u3067\u306f\u3001\u30ca\u30fc\u30eb\u30b9\u30b2\u30f3\u304c\u7dda\u7dad\u82bd\u7d30\u80de\u306e\u8ce6\u6d3b\u306b\u3064\u306a\u304c\u308a\u3001\u30a8\u30a4\u30b8\u30f3\u30b0\u30b1\u30a2\u52b9\u679c\uff08\u808c\u306e\u30cf\u30ea\uff09\u3092\u652f\u3048\u308b\u53ef\u80fd\u6027\u304c\u793a\u3055\u308c\u305f\u3002\u30ca\u30fc\u30eb\u30b9\u30b2\u30f3\u306e\u79d1\u5b66\u7684\u306a\u6839\u62e0\u3068\u3057\u3066\u5f15\u7528\u3067\u304d\u308b\u91cd\u8981\u306a\u5b66\u8853\u8ad6\u6587\u3002
\r\n\r\n\u30108\u3011Lagerstedt A-S, et al. What is sensitive skin? A systematic literature review of objective measurements. Skin Pharmacology and Physiology. 2015;28(2):75\u201385.<\/a><\/cite>
\r\n\r\nPMID: 25322670 DOI: 10.1159\/000365412
\r\n\r\n\u65e5\u672c\u8a9e\u8981\u65e8\uff1a<\/strong>\u654f\u611f\u808c\u306f\u30d0\u30ea\u30a2\u6a5f\u80fd\u4f4e\u4e0b\u3084\u8840\u7ba1\u53cd\u5fdc\u6027\u306e\u5897\u52a0\u306a\u3069\u304c\u4e3b\u306a\u7279\u5fb4\u3068\u3055\u308c\u308b\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u305f\u30b7\u30b9\u30c6\u30de\u30c6\u30a3\u30c3\u30af\u30ec\u30d3\u30e5\u30fc\u3067\u3042\u308b\u3002\u5316\u7ca7\u54c1\u30fb\u30b9\u30ad\u30f3\u30b1\u30a2\u88fd\u54c1\u306e\u9078\u629e\u306b\u306f\u523a\u6fc0\u7269\u304c\u5c11\u306a\u3044\u51e6\u65b9\u3084\u30d0\u30ea\u30a2\u5f37\u5316\u304c\u91cd\u8981\u3068\u3055\u308c\u3001\u30ca\u30fc\u30eb\u30b9\u30d4\u30e5\u30a2\u306e\u4f4e\u523a\u6fc0\u30fb\u30d0\u30ea\u30a2\u30b5\u30dd\u30fc\u30c8\u8a2d\u8a08\u304c\u654f\u611f\u808c\u3067\u3082\u4f7f\u3044\u3084\u3059\u304f\u808c\u306e\u8abf\u5b50\u3092\u6574\u3048\u308b\u3068\u3044\u3046\u8003\u3048\u65b9\u3092\u6307\u793a\u3002\r\n\r\n<\/pre>\n
 <\/p>\n
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