{"id":66597,"date":"2026-01-05T10:00:45","date_gmt":"2026-01-05T01:00:45","guid":{"rendered":"https:\/\/www.nahls.co.jp\/eijingukea\/?p=66597"},"modified":"2026-01-06T10:38:32","modified_gmt":"2026-01-06T01:38:32","slug":"new-nahlspure_kie","status":"publish","type":"post","link":"https:\/\/www.nahls.co.jp\/eijingukea\/evidences\/hiroba\/new-nahlspure_kie\/","title":{"rendered":"\u6025\u306b\u6dbc\u3057\u304f\u306a\u3063\u3066\u611f\u3058\u308b\u300c\u3086\u3089\u304e\u808c\u300d\u3067\u304a\u60a9\u307f\u306e\u65b9\u306b\u304a\u3059\u3059\u3081\uff01\u9032\u5316\u3057\u305f\u300e\u30ca\u30fc\u30eb\u30b9\u30d4\u30e5\u30a2\u300fby KIE"},"content":{"rendered":"
\n

\u6025\u306b\u6dbc\u3057\u304f\u306a\u308a\u307e\u3057\u305f\u306d\u30fb\u30fb\u30fb\u30fb\u3002\u5b63\u7bc0\u306e\u5909\u308f\u308a\u76ee\u306f\u300c\u3086\u3089\u304e\u808c\u300d\u306b\u60a9\u3080\u65b9\u3082\u591a\u3044\u306e\u3067\u306f\u306a\u3044\u3067\u3057\u3087\u3046\u304b\uff1f\uff01\u79c1\u3082\u305d\u306e\u4e00\u4eba\uff01\u65e9\u304f\u3082\u4e7e\u71e5\u304c\u6c17\u306b\u306a\u308a\u3001\u304a\u808c\u306e\u30ab\u30b5\u3064\u304d\u3084\u3001\u5c0f\u3058\u308f\u304c\u6c17\u306b\u306a\u308a\u59cb\u3081\u307e\u3057\u305f\u3002<\/p>\n

\u306a\u3093\u3068\uff01\u305d\u3093\u306a\u79c1\u306b\u3074\u3063\u305f\u308a\u306a\u30b9\u30ad\u30f3\u30b1\u30a2\u304c\u4eca\u79cb\u30ea\u30cb\u30e5\u30fc\u30a2\u30eb\u3057\u3066\u767b\u5834\uff01\u300c\u30ca\u30fc\u30eb\u30b9\u30d4\u30e5\u30a2\u300d\u304c\u9032\u5316\u3057\u307e\u3059\uff01<\/p>\n

\u305d\u3053\u3067\u3001\u30df\u30cb\u30dc\u30c8\u30eb\u3067\u306f\u3042\u308a\u307e\u3059\u304c\u3001\u4e00\u8db3\u304a\u5148\u306b\u304a\u8a66\u3057\u3055\u305b\u3066\u3044\u305f\u3060\u304d\u307e\u3057\u305f\u3002<\/p>\n<\/div>\n

1\uff0e\u30ea\u30cb\u30e5\u30fc\u30a2\u30eb\u3059\u308b\u30ca\u30fc\u30eb\u30b9\u30d4\u30e5\u30a2\u306b\u306f\u30013\u3064\u306e\u6210\u5206\u304c\u8ffd\u52a0\uff01<\/h2>\n

\"\u30ca\u30fc\u30eb\u30b9\u30d4\u30e5\u30a2\"<\/a><\/p>\n

\u2460\u30bb\u30e9\u30df\u30c9\u30d7\u30ed\u30e2\u30fc\u30bf\u30fc<\/span><\/p>\n

\u8868\u76ae\u306e\u89d2\u8cea\u5c64\u306b\u3042\u3063\u3066\u30bf\u30fc\u30f3\u30aa\u30fc\u30d0\u30fc\u306e\u904e\u7a0b\u3067\u3064\u304f\u3089\u308c\u308b\u30bb\u30e9\u30df\u30c9\u3002<\/p>\n

\u305d\u306e\u30bb\u30e9\u30df\u30c9\u3092\u5897\u3084\u3059\u7279\u5fb4\u304c\u3042\u308b\u306e\u3067\u30d0\u30ea\u30a2\u6a5f\u80fd\u3092\u6539\u5584\uff01\u4e7e\u71e5\u808c\u3084\u654f\u611f\u808c\u306e\u30b1\u30a2\u306b\u30d4\u30c3\u30bf\u30ea\u3002<\/p>\n

\u30e1\u30e9\u30cb\u30f3\u3092\u6291\u3048\u308b\u50cd\u304d\u3082\u3042\u308a\u307e\u3059\u3002<\/p>\n

\u8a73\u3057\u304f\u306f\u3001\u300c3-\u30e9\u30a6\u30ea\u30eb\u30b0\u30ea\u30bb\u30ea\u30eb\u30a2\u30b9\u30b3\u30eb\u30d3\u30f3\u9178\u306f\u30bb\u30e9\u30df\u30c9\u3092\u5897\u3084\u3059\u30d3\u30bf\u30df\u30f3C\u300d\u3092\u3054\u89a7\u304f\u3060\u3055\u3044\u3002<\/p>\n

\u2461\u30ca\u30a4\u30a2\u30b7\u30f3\u30a2\u30df\u30c9<\/span>
\n\u808c\u8352\u308c\u3001\u30b7\u30ef\u6539\u5584\u3001\u7f8e\u767d\u306e\u533b\u85ac\u90e8\u5916\u54c1\u306e\u6709\u52b9\u6210\u5206\u3068\u3057\u3066\u627f\u8a8d\u3092\u5f97\u3066\u3044\u308b\u7a00\u6709\u306a\u5316\u7ca7\u54c1\u6210\u5206\u3002<\/p>\n

\u30bb\u30e9\u30df\u30c9\u3001\u30b3\u30e9\u30fc\u30b2\u30f3\u3092\u5897\u3084\u3059\u306e\u3067\u3001\u4e7e\u71e5\u808c\u3084\u654f\u611f\u808c\u306b\u3082GOOD\u3002<\/p>\n

\u30e1\u30e9\u30cb\u30f3\u3092\u6291\u3048\u308b\u50cd\u304d\u304c\u3042\u308b\u306e\u3067\u3001\u30b7\u30df\u3084\u30bd\u30d0\u30ab\u30b9\u4e88\u9632\u306b\u3082\u671f\u5f85\u5927\uff01<\/p>\n

\u2462\u30d4\u30ed\u30ea\u30c9\u30f3\u9178\u30ab\u30eb\u30dc\u30f3\u9178\u30ca\u30c8\u30ea\u30a6\u30e0\uff08PCA-Na\uff09<\/span>
\n\u5168\u304f\u77e5\u3089\u306a\u304b\u3063\u305f\u6210\u5206\u3067\u3059\u304c\u3001\u30a2\u30df\u30ce\u9178\u306e\u4ee3\u8b1d\u7269\u306e\u3072\u3068\u3064\u3060\u305d\u3046\u3002<\/p>\n

\u5927\u8c46\u3001\u7cd6\u871c\u3001\u91ce\u83dc\u306b\u3082\u542b\u307e\u308c\u3066\u304a\u308a\u5b89\u5168\u6027\u304c\u9ad8\u3044\u6210\u5206\u306a\u3093\u3067\u3059\u3063\u3066\u3002<\/p>\n

\u6c34\u3068\u306a\u3058\u307f\u3084\u3059\u3044\u4fdd\u6e7f\u6210\u5206\u306a\u306e\u3067\u3001\u6c34\u5206\u3092\u5438\u7740\u3059\u308b\u3053\u3068\u3067\u4fdd\u6e7f\u529b\u3092\u767a\u63ee\u3057\u30d0\u30ea\u30a2\u6a5f\u80fd\u3092\u5b88\u308a\u307e\u3059\uff01<\/p>\n

\u4e7e\u71e5\u808c\u306e\u4e88\u9632\u3084\u6539\u5584\u304c\u671f\u5f85\u3067\u304d\u307e\u3059\u3002<\/p>\n

\u8a73\u3057\u304f\u306f\u3001\u300cPCA-Na\uff08\u30d4\u30ed\u30ea\u30c9\u30f3\u30ab\u30eb\u30dc\u30f3\u9178\u30ca\u30c8\u30ea\u30a6\u30e0\uff09\u5316\u7ca7\u54c1\u306e\u4fdd\u6e7f\u52b9\u679c\u3068\u5b89\u5168\u6027<\/a>\u300d\u3092\u3054\u89a7\u304f\u3060\u3055\u3044\u3002<\/p>\n

2\uff0e\u65b0\u30ca\u30fc\u30eb\u30b9\u30d4\u30e5\u30a2\u306e\u30df\u30cb\u30dc\u30c8\u30eb\u3092\u4f7f\u3063\u305f\u611f\u60f3<\/h2>\n

\"\u30ca\u30fc\u30eb\u30b9\u30d4\u30e5\u30a2\"<\/a><\/p>\n

\u65b0\u30ca\u30fc\u30eb\u30b9\u30d4\u30e5\u30a2\u306e\u30df\u30cb\u30dc\u30c8\u30eb\u3092\u4f7f\u3063\u3066\u307f\u305f\u611f\u60f3\u306f\u3001\u304a\u808c\u306b\u3064\u3051\u305f\u77ac\u9593\u304b\u3089\u30b9\u30fc\u30c3\u3068\u6d78\u900f\u3057\u3066\u3044\u304f\u611f\u3058\u304c\u3057\u3066\u3001\u3044\u3063\u3071\u3044\u30d0\u30b7\u30e3\u30d0\u30b7\u30e3\u3068\u4f7f\u308f\u306a\u304f\u3066\u3082\u808c\u304c\u6c34\u5206\u3092\u304d\u3063\u3061\u308a\u98f2\u3093\u3067\uff08\u7b11\uff09\u304f\u308c\u3066\u308b\u306e\u3092\u611f\u3058\u307e\u3059\u3002<\/p>\n

\u590f\u306e\u9593\u306b\u30c0\u30e1\u30fc\u30b8\u3092\u53d7\u3051\u305f\u808c\u306b\u52b9\u3044\u3066\u308b\u611f\u3058\uff01\u4e7e\u71e5\u3057\u3066\u3044\u305f\u808c\u304c\u8607\u308a\u307e\u3057\u305f\u3002<\/p>\n

\u4f7f\u308f\u305b\u3066\u3044\u305f\u3060\u3044\u305f\u306e\u304c\u30df\u30cb\u30dc\u30c8\u30eb\u3060\u3063\u305f\u306e\u3067\u3001\u52b9\u679c\u307e\u3067\u306f\u6642\u9593\u306e\u304b\u304b\u308b\u30e1\u30e9\u30cb\u30f3\u3092\u6291\u3048\u3066\u3001\u30b7\u30df\u3084\u30bd\u30d0\u30ab\u30b9\u4e88\u9632\u3067\u304d\u3066\u3044\u308b\u306e\u304b\u306f\u611f\u3058\u308b\u4e8b\u306f\u51fa\u6765\u307e\u305b\u3093\u3067\u3057\u305f\u304c\u3001\u5c11\u3057\u4f7f\u3063\u305f\u3060\u3051\u3067\u3001\u4fdd\u6e7f\u306e\u52b9\u679c\u3092\u5341\u5206\u306b\u611f\u3058\u305f\u306e\u3067\u3001\u7d9a\u3051\u308c\u3070\u3001\u30b7\u30df\u3084\u30bd\u30d0\u30ab\u30b9\u4e88\u9632\u3082\u671f\u5f85\u3067\u304d\u308b\u306e\u3067\u306f\u306a\u3044\u304b\u306a\u301c\u3068\u601d\u3044\u307e\u3057\u305f\u3002<\/p>\n

\u767a\u58f2\u304c\u697d\u3057\u307f\u3067\u3059\u306d\u3002<\/p>\n

\uff1c\u53c2\u8003\u8a18\u4e8b\uff1e<\/p>\n

\uff0a\u753b\u671f\u7684\u306a\u30a8\u30a4\u30b8\u30f3\u30b0\u30b1\u30a2\u5316\u7ca7\u54c1\u6210\u5206\u30ca\u30fc\u30eb\u30b9\u30b2\u30f3\u914d\u5408\u5316\u7ca7\u54c1\u300e\u30ca\u30fc\u30eb\u30b9\u300fVOl.1 by KIE<\/a><\/p>\n

\uff0a\u5316\u7ca7\u6c34\u306f90\uff05\u304c\u6c34\uff01\u30d0\u30b7\u30e3\u30d0\u30b7\u30e3\u305f\u3063\u3077\u308a\u4f7f\u3063\u3066\u3082\u4e7e\u71e5\u808c\u306f\u6539\u5584\u3057\u306a\u3044<\/a><\/p>\n

3\uff0e\u65b0\u3057\u3044\u30ca\u30fc\u30eb\u30b9\u30d4\u30e5\u30a2\u306b\u3064\u3044\u3066<\/h2>\n

KIE\u3055\u3093\u306e\u3054\u7d39\u4ecb\u306e\u3068\u304a\u308a\u3001\u65b0\u3057\u3044\u30ca\u30fc\u30eb\u30b9\u30d4\u30e5\u30a2\u306b\u306f3\u3064\u306e\u7f8e\u5bb9\u6210\u5206\u3092\u8ffd\u52a0\u3057\u307e\u3057\u305f\u3002\u3044\u305a\u308c\u3082\u30a8\u30a4\u30b8\u30f3\u30b0\u30b1\u30a2\u3084\u7f8e\u808c\u3092\u30ad\u30fc\u30d7\u3059\u308b\u305f\u3081\u306b\u5927\u5207\u306a\u6210\u5206\u3067\u3059\u3002<\/p>\n

\u307e\u305f\u3001\u523a\u6fc0\u6027\u3082\u306a\u3044\u5b89\u5168\u306a\u6210\u5206\u3067\u3059\u3002<\/p>\n

\u304d\u3063\u3068\u3001\u30d1\u30ef\u30fc\u30a2\u30c3\u30d7\u3057\u305f\u30ca\u30fc\u30eb\u30b9\u30d4\u30e5\u30a2\u304c\u30a8\u30a4\u30b8\u30f3\u30b0\u30b1\u30a2\u4e16\u4ee3\u306e\u5973\u6027\u306e\u5f37\u3044\u5473\u65b9\u306b\u306a\u3063\u3066\u304f\u308c\u308b\u306f\u305a\u3067\u3059\u3002\u3082\u3061\u308d\u3093\u3001\u3053\u308c\u307e\u3067\u306e\u30ca\u30fc\u30eb\u30b9\u30d4\u30e5\u30a2\u306b\u914d\u5408\u3057\u3066\u3044\u308b\u30ca\u30fc\u30eb\u30b9\u30b2\u30f3\u3084\u30d7\u30ed\u30c6\u30aa\u30b0\u30ea\u30ab\u30f3\u3001APPS\u306f\u305d\u306e\u307e\u307e\u914d\u5408\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n

\u4e00\u65b9\u3001\u6e1b\u3089\u3057\u305f\u6210\u5206\u306f\u306a\u3044\u306e\u3067\u52b9\u679c\u304c\u30de\u30a4\u30ca\u30b9\u306b\u306a\u308b\u70b9\u3082\u3042\u308a\u307e\u305b\u3093\u3002\u305d\u3057\u3066\u3001\u9999\u6599\u3001\u7740\u8272\u8272\u3001\u30a2\u30eb\u30b3\u30fc\u30eb\u306f\u7121\u6dfb\u52a0\u306e\u307e\u307e\u3067\u3059\u3002<\/p>\n

\u305c\u3072\u3001\u65b0\u3057\u3044\u30ca\u30fc\u30eb\u30b9\u30d4\u30e5\u30a2\u3092\u304a\u8a66\u3057\u304f\u3060\u3055\u3044\u306d\u3002<\/p>\n

\uff1c\u30ab\u30fc\u30eb\u3055\u3093\u306e\u30ca\u30fc\u30eb\u30b9\u30d4\u30e5\u30a2\u306e\u53c2\u8003\u8a18\u4e8b\uff1e<\/p>\n

\u3010\u7d04\uff11\u30f6\u6708\u4f7f\u7528\u3057\u305f\u611f\u60f3\u3011\u30ca\u30fc\u30eb\u30b9\u300c\u30d4\u30e5\u30a2\u3001\u30cd\u30aa\u3001\u30e6\u30cb\u30d0\u300dby\u30ab\u30fc\u30eb<\/a><\/p>\n

\uff1c\u53c2\u8003\u8a18\u4e8b\uff1e<\/p>\n

\uff0a\u5316\u7ca7\u6c34\u30e9\u30f3\u30ad\u30f3\u30b0\u3092\u8d85\u3048\u308b\uff01\u30a8\u30a4\u30b8\u30f3\u30b0\u30b1\u30a2\u5316\u7ca7\u6c34\u306e\u9078\u3073\u65b9<\/a><\/p>\n

\uff0a\u304a\u3059\u3059\u3081\u306e\u654f\u611f\u808c\u5316\u7ca7\u6c34\uff01\u9078\u3073\u65b9\u306f\u30e9\u30f3\u30ad\u30f3\u30b0\u3088\u308a\u523a\u6fc0\u6210\u5206\u3092\u907f\u3051\u308b<\/a><\/p>\n

\uff0a\u30a2\u30eb\u30b3\u30fc\u30eb\u30d5\u30ea\u30fc\u5316\u7ca7\u6c34\u3067\u6f64\u3044\u7d20\u808c\u3078\uff01\u5931\u6557\u3057\u306a\u3044\u9078\u3073\u65b9\u306e3\u3064\u306e\u30b3\u30c4<\/a><\/p>\n

\uff0a\u30a2\u30df\u30ce\u9178\u5316\u7ca7\u6c34\u3067\u7f8e\u808c\u306b\u306a\u308b\uff01\u52b9\u679c\u3068\u30a8\u30a4\u30b8\u30f3\u30b0\u30b1\u30a2\u306e\u30e1\u30ea\u30c3\u30c8\u306f\uff1f<\/a><\/p>\n

4\uff0e\u30ca\u30fc\u30eb\u30b9\u30a8\u30a4\u30b8\u30f3\u30b0\u30b1\u30a2\u30a2\u30ab\u30c7\u30df\u30fc\u7de8\u96c6\u90e8\u30b3\u30e1\u30f3\u30c8<\/h2>\n

\u4eca\u56de\u306e\u8a18\u4e8b\u306e\u57f7\u7b46\u3001KIE\u3055\u3093\u3001\u3042\u308a\u304c\u3068\u3046\u3054\u3056\u3044\u307e\u3057\u305f\u3002<\/p>\n

\u65b0\u3057\u3044\u30ca\u30fc\u30eb\u30d4\u30e5\u30a2\u306e\u8ffd\u52a0\u6210\u5206\u3068\u4f7f\u7528\u5b9f\u611f\u306b\u3064\u3044\u3066\u8a73\u3057\u304f\u3054\u7d39\u4ecb\u3044\u305f\u3060\u304d\u3068\u3066\u3082\u3046\u308c\u3057\u3044\u3067\u3059\u3002<\/p>\n

\u3042\u308a\u304c\u3068\u3046\u3054\u3056\u3044\u307e\u3059\u3002<\/p>\n

\u3057\u3063\u304b\u308a\u3068\u65b0\u3057\u3044\u30ca\u30fc\u30eb\u30b9\u30d4\u30e5\u30a2\u306e\u7279\u5fb4\u3092\u3054\u7d39\u4ecb\u3044\u305f\u3060\u3044\u3066\u3044\u308b\u306e\u3067\u3001\u304d\u3063\u3068KIE\u3055\u3093\u306e\u57f7\u7b46\u3044\u305f\u3060\u3044\u305f\u3053\u306e\u8a18\u4e8b\u304c\u30ca\u30fc\u30eb\u30b9\u30a8\u30a4\u30b8\u30f3\u30b0\u30b1\u30a2\u30a2\u30ab\u30c7\u30df\u30fc\u306e\u8aad\u8005\u306e\u7686\u69d8\u306b\u5f79\u7acb\u3064\u3068\u601d\u3044\u307e\u3059\u3002<\/p>\n

\u308f\u305f\u3057\u305f\u3061\u306f\u3001\u30ca\u30fc\u30eb\u30b9\u306e\u30a8\u30a4\u30b8\u30f3\u30b0\u30b1\u30a2\u5316\u7ca7\u54c1\u3092\u901a\u3057\u3066\u591a\u304f\u306e\u5973\u6027\u306e\u7f8e\u808c\u3092\u5fdc\u63f4\u3067\u304d\u308c\u3070\u3068\u8003\u3048\u3066\u3044\u307e\u3059\u3002<\/p>\n

 <\/p>\n

\uff1c\u53c2\u7167\u8ad6\u6587\uff1e<\/h2>\n
\r\n\u30101\u3011Robinson LR, Fitzgerald NC, Doughty DG, Dawes NC, Berge CA, Bissett DL.\r\nTopical palmitoyl pentapeptide provides improvement in photoaged human facial skin.Int J Cosmet Sci. 2005 Jun;27(3):155\u2013160.<\/a><\/cite>
\r\n\r\nPMID: 18492182 DOI: 10.1111\/j.1467-2494.2005.00261.x
\r\n\r\n\u65e5\u672c\u8a9e\u8981\u65e8\uff1a<\/strong>\u30b7\u30b0\u30ca\u30eb\u30da\u30d7\u30c1\u30c9\uff08Pal-KTTKS\uff09\u5916\u7528\u306e\u81e8\u5e8a\u7814\u7a76\u3002\u7d99\u7d9a\u4f7f\u7528\u3067\u5149\u8001\u5316\u306b\u4f34\u3046\u5c0f\u3058\u308f\u306a\u3069\u304c\u6539\u5584\u3057\u3001\u30da\u30d7\u30c1\u30c9\u7cfb\u6210\u5206\u304c\u30cf\u30ea\u30fb\u3057\u308f\u30b1\u30a2\u306b\u5bc4\u4e0e\u3059\u308b\u53ef\u80fd\u6027\u3092\u793a\u3057\u305f\u3002
\r\n\r\n\u30102\u3011Bissett DL, Oblong JE, Berge CA.Niacinamide: A B vitamin that improves aging facial skin appearance.Dermatol Surg. 2005;31(7 Pt 2):860\u2013865.<\/a><\/cite>
\r\n\r\nPMID: 16029679\u3000DOI: 10.1111\/j.1524-4725.2005.31726
\r\n\r\n\u65e5\u672c\u8a9e\u8981\u65e8\uff1a<\/strong>\u30ca\u30a4\u30a2\u30b7\u30f3\u30a2\u30df\u30c9\u5916\u7528\u306b\u3088\u308a\u3001\u5c0f\u3058\u308f\u3001\u8272\u30e0\u30e9\u3001\u9ec4\u3050\u3059\u307f\u3001\u30d0\u30ea\u30a2\u6a5f\u80fd\u304c\u6539\u5584\u3002\u30bb\u30e9\u30df\u30c9\u5408\u6210\u4fc3\u9032\u3084\u708e\u75c7\u6291\u5236\u3092\u901a\u3058\u3066\u3001\u30a8\u30a4\u30b8\u30f3\u30b0\u30b1\u30a2\u3068\u7f8e\u767d\u306e\u4e21\u9762\u3067\u6709\u7528\u3067\u3042\u308b\u3053\u3068\u3092\u793a\u3057\u305f\u4ee3\u8868\u7684\u7814\u7a76\u3002
\r\n\r\n\u30103\u3011Pullar JM, Carr AC, Vissers MCM.The Roles of Vitamin C in Skin Health.Nutrients. 2017;9(8):866.<\/a><\/cite>
\r\n\r\nPMID: 28805671DOI: 10.3390\/nu9080866
\r\n\r\n\u65e5\u672c\u8a9e\u8981\u65e8\uff1a<\/strong>\u30d3\u30bf\u30df\u30f3C\u306f\u30b3\u30e9\u30fc\u30b2\u30f3\u5408\u6210\u3001\u6297\u9178\u5316\u3001\u30e1\u30e9\u30cb\u30f3\u751f\u6210\u6291\u5236\u306b\u95a2\u4e0e\u3059\u308b\u91cd\u8981\u6210\u5206\u3002\u5916\u7528\u30d3\u30bf\u30df\u30f3C\u304a\u3088\u3073\u8a98\u5c0e\u4f53\u304c\u3001\u5149\u8001\u5316\u3084\u30b7\u30df\u5bfe\u7b56\u306b\u6709\u52b9\u3067\u3042\u308b\u3053\u3068\u3092\u5206\u5b50\u30ec\u30d9\u30eb\u3067\u6574\u7406\u3057\u305f\u7dcf\u8aac\u3002
\r\n\r\n\u30104\u3011Bai X-D, Liu Y-C, Ge S-Y, Fei W-C.Clinical Trial of Salmon Nasal Cartilage-Derived Proteoglycans on Human Facial Antiaging: A Randomized, Double-Blind, Placebo-Controlled Study.J Cosmet Dermatol. 2025 Jul;24(7):e70218.<\/a><\/cite>
\r\n\r\nPMID: 40613544 DOI: 10.1111\/jocd.70218
\r\n\r\n\u65e5\u672c\u8a9e\u8981\u65e8\uff1a<\/strong>\u30b5\u30b1\u9f3b\u8edf\u9aa8\u7531\u6765\u30d7\u30ed\u30c6\u30aa\u30b0\u30ea\u30ab\u30f3\u309256\u65e5\u9593\u6442\u53d6\u3057\u305f\u4e8c\u91cd\u76f2\u691cRCT\u3002\u30d7\u30e9\u30bb\u30dc\u6bd4\u3067\u808c\u306e\u5f3e\u529b\u30fb\u6c34\u5206\u304c\u6539\u5584\u3057\u3001\u7c97\u3055\u30fb\u3057\u308f\u30fb\u30e1\u30e9\u30cb\u30f3\u91cf\u30fb\u30d6\u30e9\u30a6\u30f3\u30b9\u30dd\u30c3\u30c8\u304c\u6e1b\u5c11\u3002\u30d7\u30ed\u30c6\u30aa\u30b0\u30ea\u30ab\u30f3\u306e\u201c\u808c\u30b3\u30f3\u30c7\u30a3\u30b7\u30e7\u30f3\u6539\u5584\u201d\u6839\u62e0\u3068\u3057\u3066\u4f7f\u3044\u3084\u3059\u3044\u3002
\r\n\r\n\u30105\u3011Rawlings AV, Harding CR.Moisturization and skin barrier function.Dermatol Ther. 2004;17 Suppl 1:43\u201348.<\/a><\/cite>
\r\n\r\nPMID: 14728698 DOI: 10.1111\/j.1396-0296.2004.04s1005.x
\r\n\r\n\u65e5\u672c\u8a9e\u8981\u65e8\uff1a<\/strong>\u89d2\u8cea\u5c64\u306e\u4fdd\u6e7f\u3068\u30d0\u30ea\u30a2\u6a5f\u80fd\u306e\u7dcf\u8aac\u3002NMF\uff08PCA\u306a\u3069\u306e\u30a2\u30df\u30ce\u9178\u7531\u6765\u6210\u5206\uff09\u3084\u7d30\u80de\u9593\u8102\u8cea\u304c\u6c34\u5206\u4fdd\u6301\u306b\u91cd\u8981\u3067\u3001\u5316\u7ca7\u6c34\u30fb\u4fdd\u6e7f\u5264\u306f\u300c\u6c34\u3092\u4e0e\u3048\u308b\u300d\u3060\u3051\u3067\u306a\u304f\u300c\u4fdd\u6301\u3067\u304d\u308b\u89d2\u8cea\u74b0\u5883\u3092\u4f5c\u308b\u300d\u8a2d\u8a08\u304c\u8981\u70b9\u3068\u6574\u7406\u3002
\r\n\r\n\u30106\u3011Draelos ZD.The science behind skin care: Moisturizers.J Cosmet Dermatol. 2018;17(2):138\u2013144.<\/a><\/cite>
\r\n\r\nPMID: 29319217 DOI: 10.1111\/jocd.12490
\r\n\r\n\u65e5\u672c\u8a9e\u8981\u65e8\uff1a<\/strong>\u4fdd\u6e7f\u5264\uff08\u5316\u7ca7\u6c34\uff5e\u4e73\u6db2\u30fb\u30af\u30ea\u30fc\u30e0\u542b\u3080\uff09\u306e\u79d1\u5b66\u3092\u6574\u7406\u3002\u30d2\u30e5\u30fc\u30e1\u30af\u30bf\u30f3\u30c8\uff08\u30b0\u30ea\u30bb\u30ea\u30f3\u7b49\uff09\uff0b\u30a8\u30e2\u30ea\u30a8\u30f3\u30c8\uff0b\u30aa\u30af\u30eb\u30fc\u30b7\u30d6\u306e\u7d44\u307f\u5408\u308f\u305b\u3001\u523a\u6fc0\u6027\u3001\u808c\u72b6\u614b\u306b\u5408\u308f\u305b\u305f\u9078\u629e\u304c\u91cd\u8981\u3067\u3001\u201c\u5316\u7ca7\u6c34\u9078\u3073\u306e\u8ef8\uff08\u4fdd\u6e7f\u30fb\u30d0\u30ea\u30a2\u30fb\u523a\u6fc0\uff09\u201d\u306e\u6839\u62e0\u306b\u306a\u308b\u3002
\r\n\r\n\u30107\u3011Verdier-S\u00e9vrain S, Bont\u00e9 F.Skin hydration: a review on its molecular mechanisms.J Cosmet Dermatol. 2007 Jun;6(2):75\u201382.<\/a><\/cite>
\r\n\r\nPMID: 17524122 DOI: 10.1111\/j.1473-2165.2007.00300.x
\r\n\r\n\u65e5\u672c\u8a9e\u8981\u65e8\uff1a<\/strong>\u76ae\u819a\u306e\u3046\u308b\u304a\u3044\u306f\u89d2\u8cea\u306e\u69cb\u9020\u30fbNMF\u30fb\u8102\u8cea\u30fb\u6c34\u5206\u79fb\u52d5\u304c\u9023\u52d5\u3057\u3066\u7dad\u6301\u3055\u308c\u308b\u3068\u89e3\u8aac\u3002\u7279\u306b\u30b0\u30ea\u30bb\u30ea\u30f3\u306a\u3069\u306e\u4fdd\u6e7f\u56e0\u5b50\u306e\u91cd\u8981\u6027\u3001\u4e7e\u71e5\u3067\u843d\u5c51\u304c\u9032\u3080\u6a5f\u5e8f\u3092\u6574\u7406\u3057\u3001\u201c\u3046\u308b\u304a\u3044\u3092\u4fdd\u3064\u5316\u7ca7\u6c34\u30fb\u4fdd\u6e7f\u8a2d\u8a08\u201d\u306e\u7406\u8ad6\u80cc\u666f\u3068\u3057\u3066\u5f15\u7528\u3057\u3084\u3059\u3044\u3002
\r\n\r\n<\/pre>\n
 <\/p>\n
\uff08\u7de8\u96c6\u30fb\u6821\u6b63\uff1a\u30a8\u30a4\u30b8\u30f3\u30b0\u30b1\u30a2\u30a2\u30ab\u30c7\u30df\u30fc\u7de8\u96c6\u90e8\u3000\u3084\u3059\u3060\u3068\u3082\u3088<\/a>\uff09
\n\u533b\u5b66\u51fa\u7248\u793e\u3001\u533b\u5b66\u7cfb\u5e83\u544a\u4ee3\u7406\u5e97\u306b\u3066\u7de8\u96c6\u30fb\u30e9\u30a4\u30bf\u30fc\u3068\u3057\u3066\u3001\u533b\u5e2b\u5411\u3051\u3001\u60a3\u8005\u5411\u3051\u306e\u60c5\u5831\u63d0\u4f9b\u8cc7\u6750\u3084\u66f8\u7c4d\u7b49\u306e\u8a18\u4e8b\u306e\u7de8\u96c6\u30fb\u57f7\u7b46\u3084\u3001\u56fd\u5185\u30fb\u6d77\u5916\u533b\u5b66\u4f1a\u53d6\u6750\u30fb\u8a18\u4e8b\u57f7\u7b46\u3092\u884c\u3046\u3002<\/p>\n
\u5f53\u793e\u30b9\u30bf\u30c3\u30d5\u306e\u672c\u696d\u306f\u3001\u533b\u5b66\u30fb\u85ac\u5b66\u95a2\u9023\u306e\u4e8b\u696d\u306e\u305f\u3081\u3001\u65e5\u3005\u3001\u533b\u5b66\u8ad6\u6587\u3084\u533b\u5b66\u4f1a\u306e\u767a\u8868\u306a\u3069\u306e\u6700\u65b0\u60c5\u5831\u306b\u89e6\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n
\u305d\u3093\u306a\u4e2d\u3067\u3001\u300c\u3053\u308c\u306f\uff01\u300d\u3068\u3044\u3046\u3001\u307f\u306a\u3055\u307e\u306e\u5065\u5eb7\u3065\u304f\u308a\u306e\u3054\u53c2\u8003\u306b\u306a\u308b\u3088\u3046\u306a\u60c5\u5831\u3054\u7d39\u4ecb\u3057\u305f\u308a\u3001
\n\u305d\u306e\u6642\u671f\u306b\u5408\u3063\u305f\u30b9\u30ad\u30f3\u30b1\u30a2\u3084\u30a8\u30a4\u30b8\u30f3\u30b0\u30b1\u30a2\u306e\u304a\u5f79\u7acb\u3061\u60c5\u5831\u3092\u30e1\u30fc\u30eb\u3067\u30b3\u30f3\u30d1\u30af\u30c8\u306b\u304a\u5c4a\u3051\u3057\u3066\u3044\u307e\u3059\u3002
\n\u305c\u3072\u3054\u767b\u9332\u3092\u304a\u5f85\u3061\u3057\u3066\u304a\u308a\u307e\u3059\u3002<\/p>\n
\u25b6\u30ad\u30ec\u30a4\u3068\u5065\u5eb7\u306e\u304a\u5f79\u7acb\u3061\u60c5\u5831\u304c\u5c4a\u304f\u3001\u30ca\u30fc\u30eb\u30b9\u306e\u30e1\u30eb\u30de\u30ac\u767b\u9332\u306f\u3053\u3061\u3089\u304b\u3089<\/a><\/p>\n
\u25b6\u30ca\u30fc\u30eb\u30b9\u30c1\u30e3\u30f3\u30cd\u30eb\u3092\u307f\u3066\u52d5\u753b\u3067\u30a8\u30a4\u30b8\u30f3\u30b0\u30b1\u30a2\u3092\u5b66\u307c\u3046\uff01<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"
\u6025\u306b\u6dbc\u3057\u304f\u306a\u308a\u307e\u3057\u305f\u306d\u30fb\u30fb\u30fb\u30fb\u3002\u5b63\u7bc0\u306e\u5909\u308f\u308a\u76ee\u306f\u300c\u3086\u3089\u304e\u808c\u300d\u306b\u60a9\u3080\u65b9\u3082\u591a\u3044\u306e\u3067\u306f\u306a\u3044\u3067\u3057\u3087\u3046\u304b\uff1f\uff01\u79c1 […]<\/p>\n","protected":false},"author":33,"featured_media":66598,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1967],"tags":[20,302,390],"aioseo_notices":[],"_links":{"self":[{"href":"\/eijingukea\/index.php\/wp-json\/wp\/v2\/posts\/66597"}],"collection":[{"href":"\/eijingukea\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"\/eijingukea\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"\/eijingukea\/index.php\/wp-json\/wp\/v2\/users\/33"}],"replies":[{"embeddable":true,"href":"\/eijingukea\/index.php\/wp-json\/wp\/v2\/comments?post=66597"}],"version-history":[{"count":5,"href":"\/eijingukea\/index.php\/wp-json\/wp\/v2\/posts\/66597\/revisions"}],"predecessor-version":[{"id":76654,"href":"\/eijingukea\/index.php\/wp-json\/wp\/v2\/posts\/66597\/revisions\/76654"}],"wp:featuredmedia":[{"embeddable":true,"href":"\/eijingukea\/index.php\/wp-json\/wp\/v2\/media\/66598"}],"wp:attachment":[{"href":"\/eijingukea\/index.php\/wp-json\/wp\/v2\/media?parent=66597"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"\/eijingukea\/index.php\/wp-json\/wp\/v2\/categories?post=66597"},{"taxonomy":"post_tag","embeddable":true,"href":"\/eijingukea\/index.php\/wp-json\/wp\/v2\/tags?post=66597"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}