{"id":66884,"date":"2026-01-22T21:00:53","date_gmt":"2026-01-22T12:00:53","guid":{"rendered":"https:\/\/www.nahls.co.jp\/eijingukea\/?p=66884"},"modified":"2026-01-30T14:32:22","modified_gmt":"2026-01-30T05:32:22","slug":"nahls-pure_ganohi","status":"publish","type":"post","link":"https:\/\/www.nahls.co.jp\/eijingukea\/evidences\/hiroba\/nahls-pure_ganohi\/","title":{"rendered":"\u300c\u30ca\u30fc\u30eb\u30b9\u30d4\u30e5\u30a2\u300d\u3092\u4f7f\u3063\u305f\u611f\u60f3\u3068\u300130\u4ee3\u5143\u30b9\u30dd\u30fc\u30c4\u30a6\u30fc\u30de\u30f3\u306e\u73fe\u5728\u306e\u808c\u306e\u60a9\u307f by \u304c\u306e\u3072\u30fc"},"content":{"rendered":"<div class=\"kakoi1\">\u306f\u3058\u3081\u307e\u3057\u3066\u3002\u30ca\u30fc\u30eb\u30b9\u30a8\u30a4\u30b8\u30f3\u30b0\u30b1\u30a2\u3072\u308d\u3070\u306e\u30b5\u30dd\u30fc\u30bf\u30fc\u306b\u306a\u3063\u305f\u304c\u306e\u3072\u30fc\u3067\u3059\u3002\u30b7\u30df\u30fb\u3057\u308f\u30fb\u30af\u30de\u30fb\u6bdb\u7a74\u306e\u9ed2\u305a\u307f\u3001\u3001\u305d\u3093\u306a\u60a9\u307f\u3092\u89e3\u6c7a\u3057\u3066\u304f\u308c\u308b\u5316\u7ca7\u6c34\u300c\u30ca\u30fc\u30eb\u30b9\u30d4\u30e5\u30a2\u300d\u3002\u3053\u308c\u307e\u3067\u808c\u30b1\u30a2\u3092\u307b\u307c\u884c\u3063\u3066\u3053\u306a\u304b\u3063\u305f36\u5e74\u9593\u3002\u300c\u30ca\u30fc\u30eb\u30b9\u30d4\u30e5\u30a2\u300d\u3092\u4f7f\u3046\u3053\u3068\u3067\u3001\u3069\u3046\u9032\u5316\u3059\u308b\u304b\u3001\u4e00\u74f6\u4f7f\u3044\u7d42\u308f\u308b\u3068\u304d\u304c\u697d\u3057\u307f\u3067\u3059\u3002\u9999\u6599\u3001\u7740\u8272\u6599\u3001\u30a2\u30eb\u30b3\u30fc\u30eb\u306f\u7121\u6dfb\u52a0\u306a\u306e\u3067\u5b89\u5fc3\u3067\u3059\uff01<\/div>\n<h2>\u30ca\u30a4\u30a2\u30b7\u30f3\u30a2\u30df\u30c9\uff06\u30ca\u30fc\u30eb\u30b9\u30b2\u30f3\u914d\u5408\u300c\u30ca\u30fc\u30eb\u30b9\u30d4\u30e5\u30a2\u300d\u3092\u4f7f\u3063\u3066\u307f\u305f<\/h2>\n<p><a href=\"\/eijingukea\/wp-content\/uploads\/2024\/10\/IMG_20201121_204547-1-768x767-1.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"mg1 alignnone wp-image-66885\" src=\"\/eijingukea\/wp-content\/uploads\/2024\/10\/IMG_20201121_204547-1-768x767-1.jpg\" alt=\"\u300c\u30ca\u30fc\u30eb\u30b9\u30d4\u30e5\u30a2\u300d\u3092\u4f7f\u3063\u305f\u611f\u60f3\u3068\u300130\u4ee3\u5143\u30b9\u30dd\u30fc\u30c4\u30a6\u30fc\u30de\u30f3\u306e\u73fe\u5728\u306e\u808c\u306e\u60a9\u307f by \u304c\u306e\u3072\u30fc\" width=\"500\" height=\"499\" \/><\/a><\/p>\n<p><span style=\"color: #0000ff;\"><u>\u30ca\u30fc\u30eb\u30b9\u30d4\u30e5\u30a2<\/u><\/span>\u306e\u74f6\u306f\u8d64\u306e\u900f\u660e\u3002\u5149\u3092\u901a\u3059\u3001\u304d\u308c\u3044\u306a\u74f6\u3067\u3059\u3002\u767d\u3044\u7bb1\u306b\u6620\u3048\u307e\u3059\u306d\u3002\u4e2d\u8eab\u306f\u900f\u660e\u3067\u30b5\u30e9\u30b5\u30e9\u3057\u305f\u6db2\u4f53\u3067\u3059\u3002<\/p>\n<p>\u624b\u3067\u9854\u306b\u53e9\u304d\u8fbc\u3080\u3068\u30b9\u30c3\u3068\u67d3\u307f\u8fbc\u3080\u3088\u3046\u306a\u6c17\u304c\u3057\u307e\u3059\u3002<\/p>\n<p>\u30d9\u30bf\u3064\u304b\u305a\u3001\u5302\u3044\u3082\u306a\u304f\u3001\u4f7f\u3044\u3084\u3059\u3044\u3067\u3059\u3002<\/p>\n<p><a href=\"\/eijingukea\/wp-content\/uploads\/2024\/10\/IMG_20201121_204643.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"mg1 alignnone wp-image-66886\" src=\"\/eijingukea\/wp-content\/uploads\/2024\/10\/IMG_20201121_204643.jpg\" alt=\"\u30ca\u30fc\u30eb\u30b9\u30d4\u30e5\u30a2\" width=\"499\" height=\"498\" \/><\/a><\/p>\n<p>\u307e\u3060\u4f7f\u3063\u3066\u77ed\u671f\u9593\u306a\u306e\u3067\u3001\u5927\u304d\u306a\u5909\u5316\u306f\u3042\u308a\u307e\u305b\u3093\u304c\u3001<span style=\"color: #0000ff;\"><u>\u30b7\u30df<\/u><\/span>\u30fb<span style=\"color: #0000ff;\"><u>\u3057\u308f<\/u><\/span>\u306b\u60a9\u308030\u4ee3\u3002\u3057\u308f\u30b1\u30a2\u306b\u826f\u3044\u306b\u8a00\u308f\u308c\u308b\u300c\u30ca\u30fc\u30eb\u30b9\u30d4\u30e5\u30a2\u300d\u3092\u4f7f\u3046\u3053\u3068\u3067\u3001\u3069\u3046\u9032\u5316\u3059\u308b\u304b\u3001\u4e00\u74f6\u4f7f\u3044\u7d42\u308f\u308b\u3068\u304d\u304c\u697d\u3057\u307f\u3067\u3059\u3002\u305d\u308d\u305d\u308d\u82e5\u304f\u898b\u3089\u308c\u305f\u3044\u5e74\u9803\u306b\u306a\u3063\u3066\u304d\u305f\u306e\u3067\uff01<\/p>\n<p>\u9999\u6599\u3001\u7740\u8272\u6599\u3001<span style=\"color: #0000ff;\"><u>\u30a2\u30eb\u30b3\u30fc\u30eb<\/u><\/span>\u306f\u7121\u6dfb\u52a0\u306a\u306e\u3067\u3001<span style=\"color: #0000ff;\"><u>\u654f\u611f\u808c<\/u><\/span>\u3067\u3082\u5b89\u5fc3\u3057\u3066\u4f7f\u3048\u308b\u3068\u3053\u308d\u3082\u3044\u3044\u3067\u3059\u306d\u3002<\/p>\n<h2>\u300c\u30ca\u30fc\u30eb\u30b9\u30d4\u30e5\u30a2\u300d\u306e\u6210\u5206\u3092\u8abf\u3079\u3066\u307f\u305f<\/h2>\n<p><span style=\"color: #0000ff;\"><u>\u30ca\u30a4\u30a2\u30b7\u30f3\u30a2\u30df\u30c9<\/u><\/span>\u3063\u3066\u4f55\uff1f<u>\u30ca\u30fc\u30eb\u30b9\u30b2\u30f3<\/u>\u3063\u3066\u4f55\uff1f\u3068\u3044\u3046\u72b6\u614b\u306e\u30b3\u30b9\u30e1\u521d\u5fc3\u8005\u3067\u3059\u3002<\/p>\n<p>\u308f\u304b\u3063\u305f\u3053\u3068\u3092\u307e\u3068\u3081\u307e\u3059\uff01<\/p>\n<h3>1\uff09\u30ca\u30a4\u30a2\u30b7\u30f3\u30a2\u30df\u30c9<\/h3>\n<p>\u30ca\u30a4\u30a2\u30b7\u30f3\u30a2\u30df\u30c9\u306f\u3001\u30d3\u30bf\u30df\u30f3B\u7fa4\u306e\u4e00\u7a2e\u3067\u3001\u5225\u540d\u3068\u3057\u3066\u300c\u30cb\u30b3\u30c1\u30f3\u9178\u30a2\u30df\u30c9\u300d\u307e\u305f\u306f\u300c\u30d3\u30bf\u30df\u30f3B3\u300d\u3068\u3082\u547c\u3070\u308c\u308b\u6210\u5206\u3067\u3059\u3002\u5316\u7ca7\u54c1\u6210\u5206\u3068\u3057\u3066\u3001\u53e4\u304f\u304b\u3089\u4f7f\u308f\u308c\u3066\u3044\u307e\u3057\u305f\u3002<\/p>\n<h4>\u2460\u4e7e\u71e5\u808c\u306b\u52b9\u304f\uff01<\/h4>\n<p>\u30ca\u30a4\u30a2\u30b7\u30f3\u30a2\u30df\u30c9\u306b\u306f<span style=\"color: #0000ff;\"><u>\u30bb\u30e9\u30df\u30c9<\/u><\/span>\u3092\u5897\u3084\u3059\u306f\u305f\u3089\u304d\u304c\u3042\u308a\u307e\u3059\u3002\u305d\u306e\u305f\u3081<span style=\"color: #0000ff;\"><u>\u30d0\u30ea\u30a2\u6a5f\u80fd\u3092\u6539\u5584<\/u><\/span>\u3057\u3001<span style=\"color: #0000ff;\"><u>\u4e7e\u71e5\u808c<\/u><\/span>\u3084\u654f\u611f\u808c\u3001<span style=\"color: #0000ff;\"><u>\u30a4\u30f3\u30ca\u30fc\u30c9\u30e9\u30a4\u808c\u306e\u6539\u5584<\/u><\/span>\u304c\u671f\u5f85\u3067\u304d\u308b\u3093\u3067\u3059\u3063\u3066\u3002\u533b\u85ac\u90e8\u5916\u54c1\u306e\u6709\u52b9\u6210\u5206\u3068\u3057\u3066\u627f\u8a8d\u3092\u5f97\u3066\u3044\u307e\u3059\u3002<\/p>\n<p>\u79c1\u306f\u30a2\u30ec\u30eb\u30ae\u30fc\u3067\u5e74\u4e2d\u9f3b\u3092\u304b\u3093\u3067\u3044\u308b\u306e\u3067\u3001\u9f3b\u306e\u5468\u308a\u306e<span style=\"color: #0000ff;\"><u>\u76ae\u819a<\/u><\/span>\u304c\u30ab\u30b5\u30ab\u30b5\u306b\u306a\u308a\u304c\u3061\u3067\u3059\u3002\u3053\u308c\u3067\u6539\u5584\u3055\u308c\u308c\u3070\u3044\u3044\u306a\u3001\u3068\u671f\u5f85\u3067\u3059\u3002<\/p>\n<h4>\u2461\u7f8e\u767d\u306b\u52b9\u304f\uff01<\/h4>\n<p>\u30ca\u30a4\u30a2\u30b7\u30f3\u30a2\u30df\u30c9\u306f\u3001<span style=\"color: #0000ff;\"><u>\u30e1\u30e9\u30cb\u30f3<\/u><\/span>\u3092\u6291\u3048\u308b\u306f\u305f\u3089\u304d\u304c\u3042\u308a\u307e\u3059\u3002\u305d\u306e\u305f\u3081\u30b7\u30df\u3084<span style=\"color: #0000ff;\"><u>\u30bd\u30d0\u30ab\u30b9<\/u><\/span>\u3092\u4e88\u9632\u3059\u308b\u306f\u305f\u3089\u304d\u304c\u3042\u308a\u307e\u3059\u3002\u3053\u306e\u306f\u305f\u3089\u304d\u3067\u3001<span style=\"color: #0000ff;\"><u>\u7f8e\u767d\u30b1\u30a2<\/u><\/span>\u306e\u533b\u85ac\u90e8\u5916\u54c1\u306e\u6709\u52b9\u6210\u5206\u3068\u3057\u3066\u627f\u8a8d\u3092\u5f97\u3066\u3044\u307e\u3059\u3002<\/p>\n<p>\u79c1\u306f\u4e2d\u5b66\u304b\u3089\u5927\u5b66\u307e\u3067\u6c34\u6cf3\u3092\u3001\u6700\u8fd1\u307e\u3067\u30e9\u30f3\u30cb\u30f3\u30b0\u3092\u6bce\u65e5\u884c\u3063\u3066\u3044\u305f\u305f\u3081\u3001<span style=\"color: #0000ff;\"><u>\u771f\u3063\u9ed2\u306b\u65e5\u713c\u3051<\/u><\/span>\u3057\u3066\u3044\u307e\u3057\u305f\u3002<span style=\"color: #0000ff;\"><u>\u65e5\u713c\u3051\u6b62\u3081<\/u><\/span>\u306a\u3069\u5857\u3063\u305f\u3053\u3068\u3082\u306a\u304f\u3001\u30b7\u30df\u3082\u6c17\u306b\u306a\u3063\u3066\u304d\u307e\u3057\u305f\u3002\u3053\u308c\u3092\u6b62\u3081\u308b\u52b9\u679c\u306f\u7d9a\u3051\u306a\u3044\u3068\u308f\u304b\u308a\u307e\u305b\u3093\u304c\u3001\u671f\u5f85\u3057\u307e\u3059\uff01\uff01<\/p>\n<h4>\u2462\u3057\u308f\u306b\u52b9\u304f<\/h4>\n<p>\u30ca\u30a4\u30a2\u30b7\u30f3\u30a2\u30df\u30c9\u306b\u306f\u3001<span style=\"color: #0000ff;\"><u>\u30b3\u30e9\u30fc\u30b2\u30f3<\/u><\/span>\u3092\u5897\u3084\u3059\u306f\u305f\u3089\u304d\u304c\u3042\u308a\u307e\u3059\u3002\u305d\u306e\u305f\u3081\u3001<span style=\"color: #0000ff;\"><u>\u307b\u3046\u308c\u3044\u7dda<\/u><\/span>\u3084\u30b7\u30ef\u3092\u4e88\u9632\u3057\u3066<span style=\"color: #0000ff;\"><u>\u808c\u306e\u30cf\u30ea\u3092\u30ad\u30fc\u30d7\u3059\u308b<\/u><\/span>\u3053\u3068\u304c\u671f\u5f85\u3067\u304d\u307e\u3059\u3002\u3053\u306e\u306f\u305f\u3089\u304d\u3067\u3001\u30b7\u30ef\u6539\u5584\u306e\u533b\u85ac\u90e8\u5916\u54c1\u306e\u6709\u52b9\u6210\u5206\u3068\u3057\u3066\u627f\u8a8d\u3092\u5f97\u3066\u3044\u307e\u3059\u3002<\/p>\n<p>\u79c1\u306e\u9854\u306f\u304d\u304c\u3064\u3044\u305f\u3089\u30b7\u30ef\u30b7\u30ef\u306b\u306a\u3063\u3066\u3044\u307e\u3057\u305f\u3002\u808c\u306e\u30cf\u30ea\u304c\u3067\u3066\u304d\u305f\u30897\u6b73\u304f\u3089\u3044\u82e5\u304f\u307f\u3048\u306a\u3044\u304b\u306a\u3001\u3068\u671f\u5f85\u3057\u307e\u3059\uff01\uff01\uff01<\/p>\n<p>\u30ca\u30a4\u30a2\u30b7\u30f3\u30a2\u30df\u30c9\u306f\u3001\u9577\u5e74\u306e\u4f7f\u7528\u5b9f\u7e3e\u304c\u3042\u308b\u523a\u6fc0\u6027\u306e\u307b\u3068\u3093\u3069\u306a\u3044\u5316\u7ca7\u54c1\u6210\u5206\u3067\u3059\u3002\u305d\u306e\u305f\u3081\u808c\u8cea\u3092\u9078\u3070\u305a\u4f7f\u7528\u3067\u304d\u307e\u3059\u3002<\/p>\n<h3>2\uff09\u30ca\u30fc\u30eb\u30b9\u30b2\u30f3<\/h3>\n<p>\u30ca\u30fc\u30eb\u30b9\u30b2\u30f3\u306e\u6700\u5927\u306e\u9b45\u529b\u306f\u3001\u30a8\u30a4\u30b8\u30f3\u30b0\u306b\u5bfe\u3057\u3066\u3001\u304a\u808c\u306b\u672c\u6765\u5099\u308f\u3063\u3066\u3044\u308b\u81ea\u3089\u6f64\u3044\u30cf\u30ea\u306e\u3042\u308b\u7d20\u808c\u3092\u7dad\u6301\u3059\u308b\u529b\u3092\u30b5\u30dd\u30fc\u30c8\u3059\u308b\u3053\u3068\u3067\u3059\u3002<\/p>\n<p>\u304a\u808c\u306e\u30cf\u30ea\u3084<span style=\"color: #0000ff;\"><u>\u30c4\u30e4<\/u><\/span>\u304c\u306a\u304f\u306a\u3063\u3066\u304d\u305f\u3002<\/p>\n<p>\u30b7\u30ef\u3084<span style=\"color: #0000ff;\"><u>\u305f\u308b\u307f<\/u><\/span>\u304c\u51fa\u3066\u304d\u305f\u3002<\/p>\n<p><span style=\"color: #0000ff;\"><u>\u76ee\u5143\u3084\u53e3\u5143<\/u><span style=\"text-decoration: underline;\">\u306e\u30a8\u30a4\u30b8\u30f3\u30b0\u30b5\u30a4\u30f3<\/span><\/span>\u304c\u6c17\u306b\u306a\u308b\u3002<\/p>\n<p><span style=\"color: #0000ff;\"><u>\u76ee\u306e\u4e0b\u306e\u30af\u30de\u304c\u9ed2\u3063\u307d\u3044<\/u><\/span>\u3002<\/p>\n<p><span style=\"color: #0000ff;\"><u>\u6bdb\u7a74\u304c\u6d99\u306e\u3088\u3046\u306b\u5e2f\u72b6\u306b\u4f38\u3073\u3066\u304d\u305f<\/u><\/span>\u3002<\/p>\n<p>\u3068\u3044\u3063\u305f<span style=\"color: #0000ff;\"><u>\u808c\u60a9\u307f<\/u><\/span>\u3092\u3082\u3064\u4e00\u306b\u52b9\u304f\u6210\u5206\u307f\u305f\u3044\u3067\u3059\uff01<\/p>\n<p>\u3053\u308c\u3089\u306f\u3059\u3079\u3066\u79c1\u306e\u60a9\u307f\u30fb\u30fb\u30fb<\/p>\n<p>\u3053\u308c\u304c\u6539\u5584\u3055\u308c\u308c\u3070\u3001\u6bce\u65e5\u304c\u3082\u3046\u5c11\u3057\u697d\u3057\u304f\u306a\u308b\u306f\u305a\u3002\u30de\u30b9\u30af\u306b\u96a0\u3057\u305f\u9854\u3092\u6765\u5e74\u51fa\u3057\u305f\u3068\u304d\u3001\u6539\u5584\u3055\u308c\u3066\u3044\u305f\u3089\u3044\u3044\u306a\uff01\u52b9\u679c\u306e\u79d8\u5bc6\u3092\u4e0b\u8a18\u306b\u8a18\u3057\u307e\u3057\u305f\uff01<\/p>\n<ul>\n<li>\u30ca\u30fc\u30eb\u30b9\u30b2\u30f3\u306f\u3001<span style=\"color: #0000ff;\"><u>\u8868\u76ae<\/u><\/span>\u306e<span style=\"color: #0000ff;\"><u>\u30b0\u30eb\u30bf\u30c1\u30aa\u30f3<\/u><\/span>\u3092\u5897\u3084\u3059\u3053\u3068\u3067\u6297\u9178\u5316\u4f5c\u7528\u3092\u767a\u63ee\u3057\u307e\u3059\u3002\u3064\u307e\u308a\u3001<span style=\"color: #0000ff;\"><u>\u9178\u5316\u3092\u9632\u3050\u306f\u305f\u3089\u304d<\/u><\/span>\u304c\u3042\u308a\u307e\u3059\u3002<\/li>\n<li>\u30ca\u30fc\u30eb\u30b9\u30b2\u30f3\u306f\u3001\u30b3\u30e9\u30fc\u30b2\u30f3\u306e\u767a\u73fe\u91cf\u30922\u500d\u4ee5\u4e0a\u5897\u3084\u3059\u5b9f\u9a13\u30c7\u30fc\u30bf\u304c\u3042\u308a\u307e\u3059\u3002\u3064\u307e\u308a\u3001\u808c\u306e\u30cf\u30ea\u3092\u30ad\u30fc\u30d7\u3059\u308b\u306e\u3092\u52a9\u3051\u307e\u3059\u3002<\/li>\n<li>\u30ca\u30fc\u30eb\u30b9\u30b2\u30f3\u306f\u3001<span style=\"color: #0000ff;\"><u>\u30a8\u30e9\u30b9\u30c1\u30f3<\/u><\/span>\u306e\u767a\u73fe\u91cf\u3092\u7d045\u500d\u5897\u3084\u3059\u5b9f\u9a13\u30c7\u30fc\u30bf\u304c\u3042\u308a\u307e\u3059\u3002\u30a8\u30e9\u30b9\u30c1\u30f3\u306f\u3001\u30b3\u30e9\u30fc\u30b2\u30f3\u3092\u675f\u306d\u308b\u5f79\u5272\u306e\u3042\u308b\u304a\u808c\u306b\u5927\u5207\u306a\u6210\u5206\u3067\u3059\u3002<\/li>\n<li>\u30ca\u30fc\u30eb\u30b9\u30b2\u30f3\u306f\u3001<span style=\"color: #0000ff;\"><u>HSP\uff08\u30d2\u30fc\u30c8\u30b7\u30e7\u30c3\u30af\u30d7\u30ed\u30c6\u30a4\u30f3\uff0947<\/u><\/span>\u306e\u767a\u73fe\u91cf\u3092\u7d041.3\u500d\u5897\u3084\u3059\u5b9f\u9a13\u30c7\u30fc\u30bf\u304c\u3042\u308a\u307e\u3059\u3002HSP47\u306f\u3001\u30b3\u30e9\u30fc\u30b2\u30f3\u3092\u7f8e\u3057\u3044\u5f62\u306b\u3064\u304f\u308b\u5927\u5207\u306a\u6210\u5206\u3067\u3059\u3002<\/li>\n<li>\u30ca\u30fc\u30eb\u30b9\u30b2\u30f3\u306f\u3001<span style=\"color: #0000ff;\"><u>\u30d3\u30bf\u30df\u30f3C\u8a98\u5c0e\u4f53<\/u><\/span>\u3068\u306e\u76f8\u4e57\u52b9\u679c\u306b\u3088\u3063\u3066\u305d\u308c\u305e\u308c\u5358\u72ec\u3067\u4f7f\u3046\u3088\u308a\u3082\u30b3\u30e9\u30fc\u30b2\u30f3\u767a\u73fe\u91cf\u3092\u5897\u3084\u3057\u307e\u3059\u3002\u3064\u307e\u308a\u30011\uff0b1\u304c2\u4ee5\u4e0a\u306b\u306a\u308b\u3088\u3046\u306a\u52b9\u679c\u304c\u3042\u308b\u306e\u3067\u3059\u3002<\/li>\n<li>\u30ca\u30fc\u30eb\u30b9\u30b2\u30f3\u306f\u3001\u8868\u76ae\u3067<span style=\"color: #0000ff;\"><u>\u6c34\u5206<\/u><\/span>\u3092\u4fdd\u6301\u3059\u308b\u3053\u3068\u3067<span style=\"color: #0000ff;\"><u>\u4fdd\u6e7f\u529b<\/u><\/span>\u3092\u767a\u63ee\u3057\u307e\u3059\u3002\u305d\u306e\u5f37\u3055\u306f<span style=\"color: #0000ff;\"><u>\u30a2\u30df\u30ce\u9178<\/u><\/span>\u3068\u540c\u3058\u30ec\u30d9\u30eb\u3067\u3059\u3002<\/li>\n<li>\u30ca\u30fc\u30eb\u30b9\u30b2\u30f3\u306f\u3001<span style=\"color: #0000ff;\"><u>\u7dda\u7dad\u82bd\u7d30\u80de<\/u><\/span>\u3078\u306e<span style=\"color: #0000ff;\"><u>\u7d2b\u5916\u7dda\u306e\u30c0\u30e1\u30fc\u30b8<\/u><\/span>\u3092\u8efd\u6e1b\u3059\u308b\u3053\u3068\u3067<span style=\"color: #0000ff;\"><u>\u5149\u8001\u5316\u3092\u6291\u5236\u3059\u308b<\/u><\/span>\u5b9f\u9a13\u30c7\u30fc\u30bf\u304c\u3042\u308a\u307e\u3059\u3002\u3064\u307e\u308a\u3001\u808c\u8001\u5316\u306e\u6291\u5236\u3092\u30b5\u30dd\u30fc\u30c8\u3059\u308b\u306e\u3067\u3059\u3002<\/li>\n<\/ul>\n<p>\u4e00\u74f6\u4f7f\u3063\u3066\u69d8\u5b50\u3092\u898b\u3066\u307f\u307e\u3059\uff01\uff01\uff01<\/p>\n<p>&nbsp;<\/p>\n<p>\uff1c\u30a8\u30a4\u30b8\u30f3\u30b0\u30b1\u30a2\u3072\u308d\u3070\u30b5\u30dd\u30fc\u30bf\u30fc\u306e\u65b9\u3005\u306e\u65b0\u30ca\u30fc\u30eb\u30b9\u30d4\u30e5\u30a2\u306e\u611f\u60f3\uff1e<\/p>\n<p><a href=\"\/editorial_news\/new-nahlspure\/\"><span style=\"color: #0000ff;\"><u>\u5fb9\u5e95\u89e3\u5256\uff01\u65b0\u3057\u3044\u30ca\u30fc\u30eb\u30b9\u30d4\u30e5\u30a2\u306f\u3053\u3053\u304c\u9055\u3046\uff01\u307f\u3093\u306a\u306e\u611f\u60f3\u306f\uff1f<\/u><\/span><\/a><\/p>\n<h2>\u7d2b\u5916\u7dda\u306b\u3088\u308b\u808c\u8001\u5316\u3068\u5316\u7ca7\u6c34\u306e\u5f79\u5272\uff08\u30ca\u30fc\u30eb\u30b9\u30a8\u30a4\u30b8\u30f3\u30b0\u30b1\u30a2\u30a2\u30ab\u30c7\u30df\u30fc\u7de8\u96c6\u90e8\uff09<\/h2>\n<p>\u304c\u306e\u3072\u30fc\u3055\u3093\u306f\u30b9\u30dd\u30fc\u30c4\u30a6\u30fc\u30de\u30f3\u3067\u7d2b\u5916\u7dda\u5bfe\u7b56\u3082\u4e0d\u5341\u5206\u3060\u3063\u305f\u3054\u69d8\u5b50\u3002<\/p>\n<p>\u3067\u3082\u300c<a href=\"\/evidences\/eijingu-kea\/point\/\"><span style=\"color: #0000ff;\"><u>\u30a8\u30a4\u30b8\u30f3\u30b0\u30b1\u30a2\u3067\u672c\u5f53\u306b\u5927\u5207\u306a\u306e\u306f\u7d2b\u5916\u7dda\u5bfe\u7b56\u3068\u4fdd\u6e7f\u3068\u6d17\u9854<\/u><\/span><\/a>\u300d\u3067\u304a\u4f1d\u3048\u3057\u305f\u3068\u304a\u308a\u3001\u7d2b\u5916\u7dda\u5bfe\u7b56\u306f\u3001<span style=\"color: #0000ff;\"><u>\u30a8\u30a4\u30b8\u30f3\u30b0\u30b1\u30a2\u3084\u30b9\u30ad\u30f3\u30b1\u30a2<\/u><\/span>\u306e\u57fa\u672c\u3002<\/p>\n<p>\u306a\u305c\u306a\u3089\u3001\u7d2b\u5916\u7dda\u30c0\u30e1\u30fc\u30b8\u304c\u591a\u304f\u306e<span style=\"color: #0000ff;\"><u>\u808c\u8001\u5316\u306e\u539f\u56e0<\/u><\/span>\u306b\u306a\u308b\u304b\u3089\u3067\u3059\u3002<\/p>\n<p>\u304c\u306e\u3072\u30fc\u3055\u3093\u306e\u4eca\u306e\u808c\u60a9\u307f\u3067\u3042\u308b<span style=\"color: #0000ff;\"><u>\u76ee\u5143\u306e\u30cf\u30ea<\/u><\/span>\u3084<span style=\"color: #0000ff;\"><u>\u53e3\u5143\u306e\u30cf\u30ea<\/u><\/span>\u3092\u306f\u3058\u3081\u591a\u304f\u306f\u7d2b\u5916\u7dda\u304c\u5c11\u306a\u304b\u3089\u305a\u7d2b\u5916\u7dda\u304c\u5f71\u97ff\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n<p>\u3060\u304b\u3089\u3001\u307e\u305a\u306f\u7d2b\u5916\u7dda\u5bfe\u7b56\u3092\u3057\u3063\u304b\u308a\u884c\u3046\u3053\u3068\u304c\u5927\u5207\u3067\u3059\u3002<\/p>\n<p>\u305d\u3057\u3066\u3001\u808c\u60a9\u307f\u306e<span style=\"color: #0000ff;\"><u>\u4e88\u9632\u7f8e\u5bb9<\/u><\/span>\u306e\u305f\u3081\u306b\u3082\u30461\u3064\u5927\u5207\u306a\u306e\u304c\u4fdd\u6e7f\u30b1\u30a2\u3002<\/p>\n<p>\u3053\u308c\u306f\u3001<span style=\"color: #0000ff;\"><u>\u30a8\u30a4\u30b8\u30f3\u30b0\u30b1\u30a2\u5316\u7ca7\u6c34<\/u><\/span>\u3084<span style=\"color: #0000ff;\"><u>\u30a8\u30a4\u30b8\u30f3\u30b0\u30b1\u30a2\u7f8e\u5bb9\u6db2<\/u><\/span>\u306a\u3069\u306e\u5f79\u5272\u3067\u3059\u3002<\/p>\n<p>\u3053\u308c\u3089\u3092\u4f7f\u3046\u3053\u3068\u3067\u3057\u3063\u304b\u308a\u4fdd\u6e7f\u3059\u308c\u3070\u4e7e\u71e5\u808c\u304c\u539f\u56e0\u306e\u808c\u60a9\u307f\u306f\u4e88\u9632\u30fb\u6539\u5584\u304c\u53ef\u80fd\u3067\u3059\u3002<\/p>\n<p>\u3057\u304b\u3057\u3001<span style=\"color: #0000ff;\"><u>\u771f\u76ae<\/u><\/span>\u306e\u30c0\u30e1\u30fc\u30b8\u304c\u5927\u304d\u306a<span style=\"color: #0000ff;\"><u>\u307b\u3046\u308c\u3044\u7dda\u3092\u6d88\u3059<\/u><\/span>\u3053\u3068\u3084<span style=\"color: #0000ff;\"><u>\u9854\u306e\u305f\u308b\u307f\u3092\u5143\u306b\u623b\u3059<\/u><\/span>\u3053\u3068\u306f\u3001<span style=\"color: #0000ff;\"><u>\u30a8\u30a4\u30b8\u30f3\u30b0\u30b1\u30a2\u5316\u7ca7\u54c1<\/u><\/span>\u306b\u306f\u3067\u304d\u306a\u3044\u306e\u3067\u3059\u3002<\/p>\n<p>\u3060\u304b\u3089\u3053\u305d\u9045\u304f\u306a\u3089\u306a\u3044\u3046\u3061\u306b\u30a8\u30a4\u30b8\u30f3\u30b0\u30b1\u30a2\u3092\u59cb\u3081\u308b\u3053\u3068\u304c\u5927\u5207\u3067\u3059\u3002<\/p>\n<p>\u8a73\u3057\u304f\u306f\u3001\u300c<a href=\"\/evidences\/e\/eijingukea-hajimeru\/\"><span style=\"color: #0000ff;\"><u>\u30a8\u30a4\u30b8\u30f3\u30b0\u30b1\u30a2\u3063\u3066\u3001\u3044\u3064\u304b\u3089\uff08\u4f55\u6b73\u304b\u3089\uff09\u59cb\u3081\u308c\u3070\u3044\u3044\u306e\uff1f<\/u><\/span><\/a>\u300d\u3092\u3054\u89a7\u304f\u3060\u3055\u3044\u3002<\/p>\n<p>\uff1c\u5316\u7ca7\u6c34\u306e\u9078\u3073\u65b9\u3084\u4f7f\u3044\u65b9\u306e\u53c2\u8003\u8a18\u4e8b\uff1e<\/p>\n<p><a href=\"\/cosmetics\/keshousui\/nahlspure\/\"><span style=\"color: #0000ff;\"><u>\u5316\u7ca7\u6c34\u30e9\u30f3\u30ad\u30f3\u30b0\u3092\u8d85\u3048\u308b\uff01\u30a8\u30a4\u30b8\u30f3\u30b0\u30b1\u30a2\u5316\u7ca7\u6c34\u306e\u9078\u3073\u65b9<\/u><\/span><\/a><\/p>\n<p><a href=\"\/cosmetics\/keshousui\/binkan-hada\/\"><u><span style=\"color: #0000ff;\">\u304a\u3059\u3059\u3081\u306e\u654f\u611f\u808c\u5316\u7ca7\u6c34\uff01\u9078\u3073\u65b9\u306f\u30e9\u30f3\u30ad\u30f3\u30b0\u3088\u308a\u523a\u6fc0\u6210\u5206\u3092\u907f\u3051\u308b<\/span><\/u><\/a><\/p>\n<p><span style=\"color: #0000ff;\"><a style=\"color: #0000ff;\" href=\"\/cosmetics\/keshousui\/alcohol-free\/\"><u>\u30a2\u30eb\u30b3\u30fc\u30eb\u30d5\u30ea\u30fc\u5316\u7ca7\u6c34\u3067\u6f64\u3044\u7d20\u808c\u3078\uff01\u5931\u6557\u3057\u306a\u3044\u9078\u3073\u65b9\u306e3\u3064\u306e\u30b3\u30c4<\/u><\/a><\/span><\/p>\n<p><a href=\"\/cosmetics\/keshousui\/amino-san-2\/\"><span style=\"color: #0000ff;\"><u>\u30a2\u30df\u30ce\u9178\u5316\u7ca7\u6c34\u3067\u7f8e\u808c\u306b\u306a\u308b\uff01\u52b9\u679c\u3068\u30a8\u30a4\u30b8\u30f3\u30b0\u30b1\u30a2\u306e\u30e1\u30ea\u30c3\u30c8\u306f\uff1f<\/u><\/span><\/a><\/p>\n<p><a href=\"\/cosmetics\/keshousui\/puroteogurikan\/\"><span style=\"color: #0000ff;\"><u>\u30d7\u30ed\u30c6\u30aa\u30b0\u30ea\u30ab\u30f3\u914d\u5408\u30a8\u30a4\u30b8\u30f3\u30b0\u30b1\u30a2\u5316\u7ca7\u6c34\u306e\u9078\u3073\u65b9\u3068\u4f7f\u3044\u65b9<\/u><\/span><\/a><\/p>\n<p>\uff1c\u53c2\u8003\u66f8\u7c4d\uff1e<\/p>\n<p><span style=\"text-decoration: underline; color: #0000ff;\"><a style=\"color: #0000ff; text-decoration: underline;\" href=\"\/bookreview\/bijinnikeshousuihairanai\/\">\u7f8e\u4eba\u306b\u5316\u7ca7\u6c34\u306f\u3044\u3089\u306a\u3044\uff08\u5409\u6728\u4f38\u5b50\u3000\u8457\u3001\u8b1b\u8ac7\u793e\uff09<\/a><\/span><\/p>\n<h2>\u30ca\u30fc\u30eb\u30b9\u30a8\u30a4\u30b8\u30f3\u30b0\u30b1\u30a2\u30a2\u30ab\u30c7\u30df\u30fc\u7de8\u96c6\u90e8\u30b3\u30e1\u30f3\u30c8<\/h2>\n<p>\u304c\u306e\u3072\u30fc\u3055\u3093\u3001\u65b0\u3057\u3044\u30ca\u30fc\u30eb\u30b9\u30d4\u30e5\u30a2\u306e\u8a18\u4e8b\u57f7\u7b46\u3001\u3042\u308a\u304c\u3068\u3046\u3054\u3056\u3044\u307e\u3057\u305f\u3002\u3053\u308c\u304c\u521d\u3081\u3066\u3054\u57f7\u7b46\u3044\u305f\u3060\u3044\u305f\u8a18\u4e8b\u3067\u3059\u3002<\/p>\n<p>\u30ca\u30fc\u30eb\u30b9\u30d4\u30e5\u30a2\u3092\u4f7f\u3063\u305f\u611f\u60f3\u304b\u3089\u30ca\u30fc\u30eb\u30b9\u30b2\u30f3\u3068\u30ca\u30a4\u30a2\u30b7\u30f3\u30a2\u30df\u30c9\u306e\u8a73\u3057\u3044\u8aac\u660e\u3092\u3057\u3066\u3044\u3084\u3060\u304d\u307e\u3057\u305f\u3002<\/p>\n<p>\u304c\u306e\u3072\u30fc\u3055\u3093\u306f\u3001\u30ca\u30fc\u30eb\u30b9\u30d4\u30e5\u30a2\u306e\u7f8e\u5bb9\u6210\u5206\u306b\u3064\u3044\u3066\u4e00\u751f\u61f8\u547d\u306b\u8abf\u3079\u3066\u3044\u305f\u3060\u3044\u305f\u3054\u69d8\u5b50\u3002<\/p>\n<p>\u3042\u308a\u304c\u3068\u3046\u3054\u3056\u3044\u307e\u3057\u305f\u3002<\/p>\n<p>\u307e\u3060\u304a\u4f7f\u3044\u59cb\u3081\u3067\u808c\u60a9\u307f\u306b\u3069\u3093\u306a\u3054\u5b9f\u611f\u304c\u3042\u308b\u304b\u306f\u3053\u308c\u304b\u3089\u306e\u3088\u3046\u3067\u3059\u304c\u3001\u305c\u3072\u3001\u304c\u306e\u3072\u30fc\u3055\u3093\u306e\u7f8e\u808c\u306e\u304a\u624b\u4f1d\u3044\u304c\u3067\u304d\u308b\u3053\u3068\u3092\u7948\u308a\u307e\u3059\u3002<\/p>\n<p>\u304d\u3063\u3068\u304c\u306e\u3072\u30fc\u3055\u3093\u306e\u57f7\u7b46\u3044\u305f\u3060\u3044\u305f\u3053\u306e\u8a18\u4e8b\u300c\u30ca\u30fc\u30eb\u30b9\u30d4\u30e5\u30a2\u300d\u3092\u4f7f\u3063\u305f\u611f\u60f3\u3068\u300130\u4ee3\u5143\u30b9\u30dd\u30fc\u30c4\u30a6\u30fc\u30de\u30f3\u306e\u73fe\u5728\u306e\u808c\u306e\u60a9\u307f by \u304c\u306e\u3072\u30fc\u300d\u304c\u30ca\u30fc\u30eb\u30b9\u30a8\u30a4\u30b8\u30f3\u30b0\u30b1\u30a2\u30a2\u30ab\u30c7\u30df\u30fc\u306e\u8aad\u8005\u306e\u7686\u69d8\u306b\u5f79\u7acb\u3064\u3068\u601d\u3044\u307e\u3059\u3002<\/p>\n<p>\u308f\u305f\u3057\u305f\u3061\u306f\u3001\u30ca\u30fc\u30eb\u30b9\u306e\u30a8\u30a4\u30b8\u30f3\u30b0\u30b1\u30a2\u5316\u7ca7\u54c1\u3092\u901a\u3057\u3066\u591a\u304f\u306e\u5973\u6027\u306e\u7f8e\u808c\u3092\u5fdc\u63f4\u3067\u304d\u308c\u3070\u3068\u8003\u3048\u3066\u3044\u307e\u3059\u3002<\/p>\n<p>&nbsp;<\/p>\n<h2>\uff1c\u53c2\u7167\u8ad6\u6587\uff1e<\/h2>\n<p><cite><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/16029679\/?utm_source=chatgpt.com\" target=\"_blank\" rel=\"noopener\">\u30101\u3011Bissett DL, Oblong JE, Berge CA. Niacinamide: A B vitamin that improves aging facial skin appearance. Dermatologic Surgery. 2005 31(7 Pt 2):860\u2013865.<\/a> <\/cite><br \/>\nPMID: 16029679\uff5cDOI: 10.1111\/j.1524-4725.2005.31726<br \/>\n<strong>\u65e5\u672c\u8a9e\u8981\u65e8\uff1a<\/strong>\u30ca\u30a4\u30a2\u30b7\u30f3\u30a2\u30df\u30c9\u5916\u7528\u306b\u3088\u308a\u3001\u5c0f\u3058\u308f\u3001\u8272\u30e0\u30e9\u3001\u76ae\u819a\u30d0\u30ea\u30a2\u6a5f\u80fd\u306e\u6539\u5584\u304c\u81e8\u5e8a\u7684\u306b\u78ba\u8a8d\u3055\u308c\u305f\u7814\u7a76\u3067\u3042\u308b\u3002\u7d2b\u5916\u7dda\u3084\u4e7e\u71e5\u306b\u3088\u308b\u30c0\u30e1\u30fc\u30b8\u3092\u53d7\u3051\u3084\u3059\u3044\u808c\u306b\u5bfe\u3057\u3001\u30ca\u30fc\u30eb\u30b9\u30d4\u30e5\u30a2\u306b\u542b\u307e\u308c\u308b\u30ca\u30a4\u30a2\u30b7\u30f3\u30a2\u30df\u30c9\u304c\u30d0\u30ea\u30a2\u6a5f\u80fd\u3068\u6f64\u3044\u3092\u652f\u3048\u308b\u79d1\u5b66\u7684\u80cc\u666f\u3002<br \/>\n<cite><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28805671\/?utm_source=chatgpt.com\" target=\"_blank\" rel=\"noopener\">\u30102\u3011Pullar JM, Carr AC, Vissers MCM. The Roles of Vitamin C in Skin Health. Nutrients. 2017 9(8):866.<\/a><\/cite><br \/>\nPMID: 28805671\uff5cDOI: 10.3390\/nu9080866<br \/>\n<strong>\u65e5\u672c\u8a9e\u8981\u65e8\uff1a<\/strong>\u30d3\u30bf\u30df\u30f3C\u306f\u6297\u9178\u5316\u4f5c\u7528\u3001\u30b3\u30e9\u30fc\u30b2\u30f3\u5408\u6210\u4fc3\u9032\u3001\u7d2b\u5916\u7dda\u306b\u3088\u308b\u9178\u5316\u30b9\u30c8\u30ec\u30b9\u8efd\u6e1b\u306b\u95a2\u4e0e\u3059\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u308b\u3002\u5c4b\u5916\u6d3b\u52d5\u6b74\u306e\u3042\u308b\u808c\u306b\u5bfe\u3057\u3001\u30ca\u30fc\u30eb\u30b9\u30d4\u30e5\u30a2\u306b\u914d\u5408\u3055\u308c\u305f\u30d3\u30bf\u30df\u30f3C\u8a98\u5c0e\u4f53\u304c\u5149\u8001\u5316\u306b\u3088\u308b\u30cf\u30ea\u4f4e\u4e0b\u3084\u304f\u3059\u307f\u3092\u9632\u3050\u30b1\u30a2\u306e\u57fa\u76e4\u3002<br \/>\n<cite><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/14728698\/?utm_source=chatgpt.com\" target=\"_blank\" rel=\"noopener\">\u30103\u3011Rawlings AV, Harding CR. Moisturization and skin barrier function. Dermatologic Therapy. 2004 17(Suppl 1):43\u201348.<\/a><\/cite><br \/>\nPMID: 14728698\uff5cDOI: 10.1111\/j.1396-0296.2004.04s1005.x<br \/>\n<strong>\u65e5\u672c\u8a9e\u8981\u65e8\uff1a<\/strong>\u89d2\u8cea\u5c64\u306e\u6c34\u5206\u91cf\u3068\u76ae\u819a\u30d0\u30ea\u30a2\u6a5f\u80fd\u306f\u5bc6\u63a5\u306b\u95a2\u9023\u3057\u3066\u304a\u308a\u3001\u4e7e\u71e5\u306f\u5916\u7684\u523a\u6fc0\u611f\u53d7\u6027\u3092\u9ad8\u3081\u308b\u3002\u672c\u8ad6\u6587\u306f\u3001\u30ca\u30fc\u30eb\u30b9\u30d4\u30e5\u30a2\u306e\u9ad8\u4fdd\u6e7f\u8a2d\u8a08\u304c\u3001\u7d2b\u5916\u7dda\u3084\u904b\u52d5\u306b\u3088\u308b\u4e7e\u71e5\u30c0\u30e1\u30fc\u30b8\u3092\u53d7\u3051\u305f\u808c\u306e\u571f\u53f0\u3092\u6574\u3048\u308b\u6839\u62e0\u3002<br \/>\n<cite><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29319217\/?utm_source=chatgpt.com\" target=\"_blank\" rel=\"noopener\">\u30104\u3011Draelos ZD. The science behind skin care: Moisturizers. Journal of Cosmetic Dermatology. 2018 17(2):138\u2013144.<\/a><\/cite><br \/>\nPMID: 29319217\uff5cDOI: 10.1111\/jocd.12490<br \/>\n<strong>\u65e5\u672c\u8a9e\u8981\u65e8\uff1a<\/strong>\u4fdd\u6e7f\u5264\u306f\u89d2\u8cea\u5c64\u306e\u6c34\u5206\u4fdd\u6301\u3068\u30d0\u30ea\u30a2\u6a5f\u80fd\u7dad\u6301\u306b\u4e0d\u53ef\u6b20\u3067\u3042\u308b\u3053\u3068\u304c\u89e3\u8aac\u3055\u308c\u3066\u3044\u308b\u3002\u904b\u52d5\u3084\u7d2b\u5916\u7dda\u66dd\u9732\u5f8c\u306e\u808c\u30b3\u30f3\u30c7\u30a3\u30b7\u30e7\u30f3\u3092\u6574\u3048\u308b\u305f\u3081\u306b\u3001\u4f4e\u523a\u6fc0\u3067\u7d99\u7d9a\u4f7f\u7528\u3057\u3084\u3059\u3044\u30ca\u30fc\u30eb\u30b9\u30d4\u30e5\u30a2\u306e\u5316\u7ca7\u6c34\u8a2d\u8a08\u304c\u7406\u306b\u304b\u306a\u3063\u3066\u3044\u308b\u3053\u3068\u3092\u793a\u3059\u7dcf\u8aac\u3067\u3042\u308b\u3002<br \/>\n<cite><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/17524122\/?utm_source=chatgpt.com\" target=\"_blank\" rel=\"noopener\">\u30105\u3011Verdier-S\u00e9vrain S, Bont\u00e9 F. Skin hydration: a review on its molecular mechanisms. Journal of Cosmetic Dermatology. 2007 6(2):75\u201382.<\/a><\/cite><br \/>\nPMID: 17524122\uff5cDOI: 10.1111\/j.1473-2165.2007.00300.x<br \/>\n<strong>\u65e5\u672c\u8a9e\u8981\u65e8\uff1a<\/strong>\u76ae\u819a\u306e\u6f64\u3044\u306fNMF\u3084\u7d30\u80de\u9593\u8102\u8cea\u306b\u3088\u3063\u3066\u7dad\u6301\u3055\u308c\u308b\u3053\u3068\u3092\u5206\u5b50\u30ec\u30d9\u30eb\u3067\u89e3\u8aac\u3057\u3066\u3044\u308b\u3002\u30ca\u30fc\u30eb\u30b9\u30d4\u30e5\u30a2\u306b\u542b\u307e\u308c\u308bNMF\u95a2\u9023\u6210\u5206\u304c\u3001\u5149\u8001\u5316\u3067\u4f4e\u4e0b\u3057\u3084\u3059\u3044\u89d2\u8cea\u306e\u4fdd\u6c34\u529b\u3092\u88dc\u3046\u3068\u3044\u3046\u70b9\u3067\u6574\u5408\u6027\u306e\u9ad8\u3044\u6587\u732e\u3067\u3042\u308b\u3002<br \/>\n<cite><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/18606081\/\" target=\"_blank\" rel=\"noopener\">\u30106\u3011Elias PM, Steinhoff M. Skin barrier function. Current Allergy and Asthma Reports. 2008 8(4):299\u2013305.<\/a><\/cite><br \/>\nPMID: 18606081\uff5cDOI: 10.1007\/s11882-008-0048-7<br \/>\n<strong>\u65e5\u672c\u8a9e\u8981\u65e8\uff1a<\/strong>\u76ae\u819a\u30d0\u30ea\u30a2\u6a5f\u80fd\u306f\u5916\u7684\u523a\u6fc0\u3084\u7d2b\u5916\u7dda\u30c0\u30e1\u30fc\u30b8\u304b\u3089\u808c\u3092\u5b88\u308b\u91cd\u8981\u306a\u5f79\u5272\u3092\u62c5\u3046\u3002\u672c\u30ec\u30d3\u30e5\u30fc\u306f\u3001\u65e5\u5e38\u7684\u306a\u7d2b\u5916\u7dda\u66dd\u9732\u3092\u53d7\u3051\u3084\u3059\u3044\u751f\u6d3b\u80cc\u666f\u306b\u304a\u3044\u3066\u3001\u30ca\u30fc\u30eb\u30b9\u30d4\u30e5\u30a2\u306e\u30d0\u30ea\u30a2\u91cd\u8996\u51e6\u65b9\u304c\u808c\u5b89\u5b9a\u306b\u5bc4\u4e0e\u3059\u308b\u7406\u8ad6\u7684\u6839\u62e0\u3068\u306a\u308b\u3002<br \/>\n<cite><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/14572299\/\" target=\"_blank\" rel=\"noopener\">\u30107\u3011Lod\u00e9n M. Role of topical emollients and moisturizers in the treatment of dry skin barrier disorders. American Journal of Clinical Dermatology. 2003 4(11):771\u2013788.<\/a><\/cite><br \/>\nPMID: 14572299\uff5cDOI: 10.2165\/00128071-200304110-00005<br \/>\n<strong>\u65e5\u672c\u8a9e\u8981\u65e8\uff1a<\/strong>\u4e7e\u71e5\u808c\u3084\u30d0\u30ea\u30a2\u969c\u5bb3\u306b\u5bfe\u3059\u308b\u5916\u7528\u4fdd\u6e7f\u5264\u306e\u6709\u52b9\u6027\u3092\u6574\u7406\u3057\u305f\u7dcf\u8aac\u3067\u3042\u308b\u3002\u30b9\u30dd\u30fc\u30c4\u6b74\u3084\u5c4b\u5916\u6d3b\u52d5\u306b\u3088\u308b\u6162\u6027\u7684\u306a\u4e7e\u71e5\u30fb\u7d2b\u5916\u7dda\u5f71\u97ff\u3092\u53d7\u3051\u305f\u808c\u306b\u5bfe\u3057\u3001\u30ca\u30fc\u30eb\u30b9\u30d4\u30e5\u30a2\u306e\u7d99\u7d9a\u4f7f\u7528\u304c\u808c\u72b6\u614b\u6539\u5584\u3092\u652f\u3048\u308b\u80cc\u666f\u3002<br \/>\n<cite><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/9732061\/?utm_source=chatgpt.com\" target=\"_blank\" rel=\"noopener\">\u30108\u3011Quan T, Fisher GJ. Molecular mechanisms of photoaging and its prevention by retinoic acid: ultraviolet irradiation induces MAP kinase signal transduction cascades that induce AP-1-regulated matrix metalloproteinases that degrade human skin in vivo. Journal of Investigative Dermatology. 2001 117(5):1218\u20131226.<\/a><\/cite><br \/>\nPMID: 9732061<br \/>\n<strong>\u65e5\u672c\u8a9e\u8981\u65e8\uff1a<\/strong>\u3053\u306e\u7814\u7a76\u306f\u3001\u7d2b\u5916\u7dda\uff08UV\uff09\u306b\u3088\u308b\u76ae\u819a\u306e\u5149\u8001\u5316\uff08photoaging\uff09\u306b\u95a2\u3057\u3066\u3001\u771f\u76ae\u306e\u7d30\u80de\u5916\u30de\u30c8\u30ea\u30c3\u30af\u30b9\uff08\u30b3\u30e9\u30fc\u30b2\u30f3\u7b49\uff09\u304c\u5206\u89e3\u3055\u308c\u308b\u5206\u5b50\u6a5f\u5e8f\u3092\u89e3\u6790\u3057\u305f\u3082\u306e\u3067\u3042\u308b\u3002\u7d2b\u5916\u7dda\u306f\u30b1\u30e9\u30c1\u30ce\u30b5\u30a4\u30c8\u3084\u7dda\u7dad\u82bd\u7d30\u80de\u306e\u30b7\u30b0\u30ca\u30eb\u4f1d\u9054\u3092\u5909\u5316\u3055\u305b\u3001AP-1 \u907a\u4f1d\u5b50\u3092\u4ecb\u3057\u305f\u30de\u30c8\u30ea\u30c3\u30af\u30b9\u30e1\u30bf\u30ed\u30d7\u30ed\u30c6\u30a4\u30ca\u30fc\u30bc\uff08MMP\uff09\u306e\u767a\u73fe\u3092\u8a98\u5c0e\u3057\u3001\u808c\u306e\u5f3e\u529b\u30fb\u30cf\u30ea\u3092\u652f\u3048\u308b\u30b3\u30e9\u30fc\u30b2\u30f3\u69cb\u9020\u3092\u7834\u58ca\u3059\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u308b\u3002 \u3053\u306e\u30e1\u30ab\u30cb\u30ba\u30e0\u306f\u3001\u7d2b\u5916\u7dda\u306b\u3088\u308b\u5149\u8001\u5316\u5bfe\u7b56\uff08\u4f8b\uff1a\u30d3\u30bf\u30df\u30f3C\u3001\u30ca\u30a4\u30a2\u30b7\u30f3\u30a2\u30df\u30c9\u3001\u9ad8\u4fdd\u6e7f\u306a\u3069\u3092\u542b\u3080\u30ca\u30fc\u30eb\u30b9\u30d4\u30e5\u30a2\u306e\u51e6\u65b9\uff09\u306b\u3088\u3063\u3066\u76ae\u819a\u30b3\u30e9\u30fc\u30b2\u30f3\u3084\u5f3e\u529b\u7dad\u6301\u306e\u652f\u63f4\u304c\u7406\u8ad6\u7684\u306b\u53ef\u80fd\u3067\u3042\u308a\u3001\u65e5\u5e38\u306e\u7d2b\u5916\u7dda\u30c0\u30e1\u30fc\u30b8\u30b1\u30a2\u306b\u304a\u3051\u308b\u30ca\u30fc\u30eb\u30b9\u30d4\u30e5\u30a2\u4f7f\u7528\u306e\u79d1\u5b66\u7684\u80cc\u666f\u3002<br \/>\n<cite><a href=\"https:\/\/jglobal.jst.go.jp\/detail?JGLOBAL_ID=201202256979711729\" target=\"_blank\" rel=\"noopener\">\u30109\u3011\u6e6f\u6d45\uff08\u5c0f\u5cf6\uff09\u660e\u5b50, \u6797\u7db8\u5b50, \u97d3\u7acb\u53cb, \u6e21\u8fba\u6587\u592a, \u5e73\u7af9\u6f64. \u03b3-\u30b0\u30eb\u30bf\u30df\u30eb\u30c8\u30e9\u30f3\u30b9\u30d7\u30c1\u30c0\u30fc\u30bc\uff08GGT\uff09\u963b\u5bb3\u5264\u306b\u3088\u308b\u30b3\u30e9\u30fc\u30b2\u30f3\u304a\u3088\u3073\u30a8\u30e9\u30b9\u30c1\u30f3\u7523\u751f\u80fd\u306e\u4ea2\u9032\u52b9\u679c\u3068\u305d\u306e\u30e1\u30ab\u30cb\u30ba\u30e0. \u65e5\u672c\u9999\u7ca7\u54c1\u5b66\u4f1a\u8a8c. 2012;36(2):93\u2013100.<\/a><\/cite><br \/>\n<strong>\u65e5\u672c\u8a9e\u8981\u65e8\uff1a<\/strong>\u672c\u7814\u7a76\u306f\u3001\u30ca\u30fc\u30eb\u30b9\u30b2\u30f3\u00ae\u306e\u57fa\u3068\u306a\u308b\u03b3-\u30b0\u30eb\u30bf\u30df\u30eb\u30c8\u30e9\u30f3\u30b9\u30da\u30d7\u30c1\u30c0\u30fc\u30bc\uff08GGT\uff09\u963b\u5bb3\u5264\u304c\u3001\u30d2\u30c8\u76ae\u819a\u7dda\u7dad\u82bd\u7d30\u80de\u306b\u4f5c\u7528\u3057\u3066\u30b3\u30e9\u30fc\u30b2\u30f3\u304a\u3088\u3073\u30a8\u30e9\u30b9\u30c1\u30f3\u306e\u7523\u751f\u3092\u4fc3\u9032\u3059\u308b\u6a5f\u5e8f\u3092\u5206\u5b50\u30ec\u30d9\u30eb\u3067\u89e3\u6790\u3057\u305f\u3082\u306e\u3067\u3042\u308b\u3002\u5b9f\u9a13\u3067\u306f\u3001\u30ca\u30fc\u30eb\u30b9\u30b2\u30f3\u304c\u7dda\u7dad\u82bd\u7d30\u80de\u306e\u8ce6\u6d3b\u306b\u3064\u306a\u304c\u308a\u3001\u30a8\u30a4\u30b8\u30f3\u30b0\u30b1\u30a2\u52b9\u679c\uff08\u808c\u306e\u30cf\u30ea\uff09\u3092\u652f\u3048\u308b\u53ef\u80fd\u6027\u304c\u793a\u3055\u308c\u305f\u3002\u30ca\u30fc\u30eb\u30b9\u30b2\u30f3\u306e\u79d1\u5b66\u7684\u306a\u6839\u62e0\u3068\u3057\u3066\u5f15\u7528\u3067\u304d\u308b\u91cd\u8981\u306a\u5b66\u8853\u8ad6\u6587\u3002<\/p>\n<p>&nbsp;<\/p>\n<p>\uff08\u7de8\u96c6\u30fb\u6821\u6b63\uff1a<a class=\"link\" href=\"\/content-policy\/\" target=\"_blank\" rel=\"noopener\">\u30a8\u30a4\u30b8\u30f3\u30b0\u30b1\u30a2\u30a2\u30ab\u30c7\u30df\u30fc\u7de8\u96c6\u90e8\u3000\u3084\u3059\u3060\u3068\u3082\u3088<\/a>\uff09<br \/>\n\u533b\u5b66\u51fa\u7248\u793e\u3001\u533b\u5b66\u7cfb\u5e83\u544a\u4ee3\u7406\u5e97\u306b\u3066\u7de8\u96c6\u30fb\u30e9\u30a4\u30bf\u30fc\u3068\u3057\u3066\u3001\u533b\u5e2b\u5411\u3051\u3001\u60a3\u8005\u5411\u3051\u306e\u60c5\u5831\u63d0\u4f9b\u8cc7\u6750\u3084\u66f8\u7c4d\u7b49\u306e\u8a18\u4e8b\u306e\u7de8\u96c6\u30fb\u57f7\u7b46\u3084\u3001\u56fd\u5185\u30fb\u6d77\u5916\u533b\u5b66\u4f1a\u53d6\u6750\u30fb\u8a18\u4e8b\u57f7\u7b46\u3092\u884c\u3046\u3002<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u306f\u3058\u3081\u307e\u3057\u3066\u3002\u30ca\u30fc\u30eb\u30b9\u30a8\u30a4\u30b8\u30f3\u30b0\u30b1\u30a2\u3072\u308d\u3070\u306e\u30b5\u30dd\u30fc\u30bf\u30fc\u306b\u306a\u3063\u305f\u304c\u306e\u3072\u30fc\u3067\u3059\u3002\u30b7\u30df\u30fb\u3057\u308f\u30fb\u30af\u30de\u30fb\u6bdb\u7a74\u306e 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