{"id":67788,"date":"2026-01-05T07:10:37","date_gmt":"2026-01-04T22:10:37","guid":{"rendered":"https:\/\/www.nahls.co.jp\/eijingukea\/?p=67788"},"modified":"2026-01-05T08:37:54","modified_gmt":"2026-01-04T23:37:54","slug":"nahls-form-ank","status":"publish","type":"post","link":"https:\/\/www.nahls.co.jp\/eijingukea\/evidences\/hiroba\/nahls-form-ank\/","title":{"rendered":"\u5929\u7136\u30d1\u30d1\u30a4\u30f3\u914d\u5408\u306e\u9175\u7d20\u6d17\u9854\u30d1\u30a6\u30c0\u30fc\u300e\u30ca\u30fc\u30eb\u30b9\u30d5\u30a9\u30fc\u30e0\u300fby\u30a2\u30f3\u30af\u2606"},"content":{"rendered":"
\n

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 <\/p>\n

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\n\u30fb\u9069\u5ea6\u306a\u6d17\u6d44\u529b<\/span><\/span>
\n\u30fb\u4e0d\u8981\u306a\u89d2\u8cea\u3060\u3051\u3092\u9664\u53bb<\/span><\/span>
\n\u30fb\u4f4e\u523a\u6fc0<\/span><\/span>
\n\u30fb\u3057\u3063\u3068\u308a\u3057\u305f\u6d17\u3044\u4e0a\u304c\u308a<\/span><\/span><\/p>\n

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\"\u30ca\u30fc\u30eb\u30b9\u30d5\u30a9\u30fc\u30e0\"<\/a><\/p>\n

 <\/p>\n

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\n\u5b9f\u306f\u3001\u304a\u808c\u306e\u89d2\u8cea\u3084\u6bdb\u7a74\u306e\u89d2\u6813<\/span>\u306e70\uff05\u304c\u3001\u300c\u305f\u3093\u3071\u304f\u8cea\u300d\u3067\u3001\u6b8b\u308a30\uff05\u304c\u76ae\u8102<\/span>\u306a\u3069\u306e\u6cb9\u5206\u3002
\n\u77f3\u3051\u3093\u3067\u6cb9\u5206\u306f\u843d\u3068\u305b\u3066\u3082\u3001\u305f\u3093\u3071\u304f\u8cea\u3092\u6d17\u3044\u6d41\u3059\u3053\u3068\u306f\u3067\u304d\u306a\u3044\u306e\u3067\u3059\u3002
\n\u305d\u3053\u3067\u3001\u5929\u7136\u306e\u30d1\u30d1\u30a4\u30f3\u306e\u529b\u3092\u501f\u308a\u308b\u3053\u3068\u306b\uff01<\/p>\n

\"\u30d1\u30d1\u30a4\u30e4\"<\/a><\/p>\n

 <\/p>\n

3\uff0e\u6d17\u9854\u5f8c\u306e\u3057\u3063\u3068\u308a\u611f\u306e\u79d8\u5bc6\u306f\uff1f<\/h2>\n

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\u30bf\u30eb\u30af<\/span><\/b><\/code><\/p>\n

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\n\u304a\u808c\u306e\u8868\u9762\u3092\u6ed1\u3089\u304b\u306b\u3057\u3066\u76ae\u819a<\/span>\u540c\u58eb\u306e\u6469\u64e6\u3092\u8efd\u6e1b\u3055\u305b\u308b\u3053\u3068\u3067\u3001\u4f59\u8a08\u306a\u523a\u6fc0\u3092\u4e88\u9632\u3057\u3001\u3042\u305b\u3082\u306a\u3069\u3092\u9632\u3044\u3067\u304f\u308c\u308b\u306e\u3067\u3059\u3002
\n\u523a\u6fc0\u306e\u5c11\u306a\u3044\u6d17\u9854\u306e\u305f\u3081\u306b\u914d\u5408\u3057\u307e\u3057\u305f\u3002<\/p>\n

\u30b7\u30ea\u30ab<\/b><\/code><\/span><\/p>\n

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 <\/p>\n

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20<\/span><\/u>\u4ee3\u308430<\/u>\u4ee3\u306e\u9175\u7d20\u6d17\u9854\uff01\u5931\u6557\u306710<\/u>\u5e74\u5f8c\u306b\u7f8e\u808c\u304b\u3089\u8001\u3051\u9854<\/u><\/span><\/a><\/span><\/p>\n

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<\/h2>\n

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 <\/p>\n

\uff1c\u53c2\u7167\u8ad6\u6587\uff1e<\/h2>\n
\r\n\u30101\u3011Trevisol TC, Henriques RO, Souza AJ, Furigo Jr A.An overview of the use of proteolytic enzymes as exfoliating agents.J Cosmet Dermatol. 2022;21(8):3300\u20133307.<\/a>
\r\n\r\n<\/cite>PMID: 34897928\u3000DOI: 10.1111\/jocd.14673
\r\n\r\n\u65e5\u672c\u8a9e\u8981\u65e8\uff1a<\/strong>\u30d7\u30ed\u30c6\u30a2\u30fc\u30bc\uff08\u9175\u7d20\uff09\u306f\u89d2\u8cea\u5c64\u306e\u30bf\u30f3\u30d1\u30af\u8cea\u7d50\u5408\u3092\u52a0\u6c34\u5206\u89e3\u3059\u308b\u89e6\u5a92\u3068\u3057\u3066\u3001\u76ae\u819a\u306e\u30a8\u30af\u30b9\u30d5\u30a9\u30ea\u30a8\u30fc\u30b7\u30e7\u30f3\uff08\u89d2\u8cea\u9664\u53bb\u4f5c\u7528\uff09 \u3092\u793a\u3059\u3053\u3068\u304c\u591a\u6570\u306e\u57fa\u790e\u30fb\u81e8\u5e8a\u7814\u7a76\u3067\u793a\u3055\u308c\u3066\u3044\u308b\u3002\u672c\u30ec\u30d3\u30e5\u30fc\u3067\u306f\u3001\u30d1\u30d1\u30a4\u30f3\u3001\u30d6\u30ed\u30e1\u30ea\u30f3\u3001\u5fae\u751f\u7269\u7531\u6765\u30d7\u30ed\u30c6\u30a2\u30fc\u30bc\u306a\u3069\u304c\u6b7b\u3093\u3060\u89d2\u8cea\u7d30\u80de\u3084\u30bf\u30f3\u30d1\u30af\u8cea\u6027\u306e\u89d2\u6813\u6210\u5206\u3092\u5206\u89e3\u3057\u3001\u76ae\u819a\u8868\u9762\u306e\u30c6\u30af\u30b9\u30c1\u30e3\u6539\u5584\u306b\u5bc4\u4e0e\u3059\u308b\u53ef\u80fd\u6027\u304c\u6574\u7406\u3055\u308c\u3066\u3044\u308b\u3002\r\n\u7279\u306b\u3001\u3053\u308c\u3089\u9175\u7d20\u3092\u542b\u3080\u6d17\u9854\u6599\u30fb\u6d17\u6d44\u30d5\u30a9\u30fc\u30df\u30e5\u30e9\u306f\u3001\u89d2\u8cea\u80a5\u539a\u30fb\u89d2\u6813\u5f62\u6210\u306b\u95a2\u9023\u3059\u308b\u8868\u76ae\u69cb\u9020\u3092\u7a4f\u3084\u304b\u306b\u5265\u96e2\u3057\u3001\u6bdb\u7a74\u5468\u56f2\u306e\u505c\u6ede\u3057\u305f\u6c5a\u308c\u611f\u3092\u8efd\u6e1b\u3059\u308b\u4f5c\u7528\u304c\u671f\u5f85\u3055\u308c\u308b\u3068\u3055\u308c\u308b\u3002\u9175\u7d20\u6d3b\u6027\u4fdd\u6301\u306e\u305f\u3081\u306epH\u30fb\u5b89\u5b9a\u6027\u8a2d\u8a08\u3082\u91cd\u8981\u306a\u70b9\u3068\u3057\u3066\u307e\u3068\u3081\u3089\u308c\u3066\u3044\u308b\u3002
\r\n\r\n\u30102\u3011Kuntom A, Kifli H, Lim PK.Chemical and physical characteristics of soap made from distilled fatty acids of palm oil and palm kernel oil.JAOCS, Journal of the American Oil Chemists\u2019 Society. 1996;73(1):105\u2013108.<\/a><\/cite>
\r\n\r\nDOI: 10.1007\/BF02523455
\r\n\r\n\u65e5\u672c\u8a9e\u8981\u65e8:<\/strong>\u672c\u7814\u7a76\u306f\u3001\u7cbe\u5bc6\u306b\u84b8\u7559\u30fb\u5206\u7559\u3055\u308c\u305f\u8102\u80aa\u9178\uff08distilled fatty acids\uff09 \u3092\u539f\u6599\u3068\u3057\u3066\u88fd\u9020\u3057\u305f\u77f3\u3051\u3093\u306b\u3064\u3044\u3066\u3001\u5316\u5b66\u7684\u304a\u3088\u3073\u7269\u7406\u7684\u7279\u6027\u3092\u8a55\u4fa1\u3057\u305f\u3082\u306e\u3067\u3042\u308b\u3002\r\n\r\n\u30d1\u30fc\u30e0\u6cb9\u304a\u3088\u3073\u30d1\u30fc\u30e0\u6838\u6cb9\u7531\u6765\u306e\u84b8\u7559\u8102\u80aa\u9178\u304b\u3089\u4f5c\u88fd\u3057\u305f\u77f3\u3051\u3093\u306f\u3001\u8102\u80aa\u9178\u7d44\u6210\u304c\u5747\u4e00\u3067\u3001\u4e0d\u7d14\u7269\uff08\u672a\u53cd\u5fdc\u7269\u3084\u526f\u751f\u6210\u7269\uff09\u304c\u5c11\u306a\u3044\u3053\u3068\u304c\u78ba\u8a8d\u3055\u308c\u305f\u3002\r\n\r\n\u305d\u306e\u7d50\u679c\u3001\uff1c\u767d\u5ea6\u304c\u9ad8\u3044\u3001\u786c\u3055\u304c\u5b89\u5b9a\u3057\u3066\u3044\u308b\u3001\u6ce1\u7acb\u3061\u30fb\u6ce1\u306e\u5b89\u5b9a\u6027\u306b\u512a\u308c\u308b\u3001\u54c1\u8cea\u306e\u3070\u3089\u3064\u304d\u304c\u5c11\u306a\u3044\uff1e\u3068\u3044\u3063\u305f\u3001\u77f3\u3051\u3093\u3068\u3057\u3066\u91cd\u8981\u306a\u54c1\u8cea\u7279\u6027\u304c\u826f\u597d\u3067\u3042\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u305f\u3002\u8457\u8005\u3089\u306f\u3001\u8102\u80aa\u9178\u3092\u84b8\u7559\u5de5\u7a0b\u306b\u3088\u3063\u3066\u9ad8\u5ea6\u306b\u7cbe\u88fd\u30fb\u5236\u5fa1\u3059\u308b\u3053\u3068\u304c\u3001\u5b89\u5b9a\u3057\u305f\u54c1\u8cea\u3068\u4f7f\u7528\u611f\u3092\u3082\u3064\u9ad8\u54c1\u8cea\u77f3\u3051\u3093\u306e\u88fd\u9020\u306b\u6709\u52b9\u3067\u3042\u308b\u3068\u7d50\u8ad6\u3065\u3051\u3066\u3044\u308b\u3002\r\n\r\n\u672c\u7814\u7a76\u306f\u3001\u300c\u7cbe\u5bc6\u84b8\u7559\u77f3\u3051\u3093\u300d\u304c\u3001\u539f\u6599\u6bb5\u968e\u3067\u306e\u7d14\u5ea6\u7ba1\u7406\u3068\u8102\u80aa\u9178\u7d44\u6210\u306e\u6700\u9069\u5316\u3092\u901a\u3058\u3066\u3001\u54c1\u8cea\u9762\u3067\u306e\u512a\u4f4d\u6027\u3092\u6301\u3064\u88fd\u6cd5\u3067\u3042\u308b\u3053\u3068\u3092\u5b66\u8853\u7684\u306b\u88cf\u4ed8\u3051\u308b\u4ee3\u8868\u7684\u306a\u8ad6\u6587\u3067\u3042\u308b\u3002
\r\n\r\n\u30103\u3011Trevisol TC, Henriques RO, Cesca K, et al.In vitro effect on the proteolytic activity of papain with proteins of the skin as substrate.Int J Cosmet Sci. 2022 Oct;44(5):542\u2013554.<\/a>
\r\n\r\n<\/cite>PMID: 35892222 DOI: 10.1111\/ics.12805
\r\n\r\n\u65e5\u672c\u8a9e\u8981\u65e8\uff1a<\/strong>\u30d1\u30d1\u30a4\u30f3\u9175\u7d20\u306e\u30d7\u30ed\u30c6\u30a2\u30fc\u30bc\u6d3b\u6027\u3092\u3001\u76ae\u819a\u30bf\u30f3\u30d1\u30af\u8cea\uff08\u30b1\u30fc\u30b9\u30a4\u30f3\u30fb\u30b3\u30e9\u30fc\u30b2\u30f3\u30fb\u30b1\u30e9\u30c1\u30f3\u7b49\uff09\u3092\u57fa\u8cea\u3068\u3057\u3066\u8a55\u4fa1\u3002pH\u30fb\u6fc3\u5ea6\u30fb\u6e29\u5ea6\u306b\u5fdc\u3058\u3066\u9175\u7d20\u6d3b\u6027\u304c\u5909\u52d5\u3057\u3001\u89d2\u8cea\u5c64\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u52a0\u6c34\u5206\u89e3\uff08\u89d2\u8cea\u5265\u96e2\uff09 \u304c\u8d77\u3053\u308b\u3053\u3068\u3092\u793a\u3057\u305f\u3002\u9175\u7d20\u6d17\u9854\u5264\u8a2d\u8a08\u306e\u79d1\u5b66\u7684\u57fa\u76e4\u3068\u3057\u3066\u5f15\u7528\u53ef\u80fd\u3002
\r\n\r\n\u30104\u3011Avila Rodr\u00edguez MI, Rodr\u00edguez Barroso LG, S\u00e1nchez ML.Collagen: A review on its sources and potential cosmetic applications.J Cosmet Dermatol. 2018 Feb;17(1):20\u201326.<\/cite><\/a>
\r\n\r\n<\/cite>PMID: 29144022 DOI: 10.1111\/jocd.12450
\r\n\r\n\u65e5\u672c\u8a9e\u8981\u65e8\uff1a<\/strong>\u30b3\u30e9\u30fc\u30b2\u30f3\u306e\u4e3b\u8981\u4f9b\u7d66\u6e90\uff08\u9b5a\u76ae\u306a\u3069\u6d77\u6d0b\u7531\u6765\u3092\u542b\u3080\uff09\u3068\u3001\u5316\u7ca7\u54c1\u539f\u6599\u3068\u3057\u3066\u306e\u7279\u5fb4\uff08\u4fdd\u6e7f\u30fb\u76ae\u819c\u5f62\u6210\u30fb\u611f\u89e6\u6539\u826f\u306a\u3069\uff09\u3092\u7dcf\u8aac\u3068\u3057\u3066\u6574\u7406\u3057\u305f\u8ad6\u6587\u3002\u5916\u7528\u30b3\u30e9\u30fc\u30b2\u30f3\u306f\u89d2\u5c64\u8868\u9762\u3067\u6c34\u5206\u4fdd\u6301\u3084\u76ae\u819c\u5f62\u6210\u3092\u901a\u3058\u3066\u3001\u4e7e\u71e5\u306b\u3088\u308b\u3056\u3089\u3064\u304d\u30fb\u3064\u3063\u3071\u308a\u611f\u306e\u8efd\u6e1b\u306b\u5bc4\u4e0e\u3057\u3046\u308b\u3002\u6d17\u9854\u5264\u306b\u914d\u5408\u3059\u308b\u5834\u5408\u3001\u754c\u9762\u6d3b\u6027\u5264\u6d17\u6d44\u5f8c\u306e\u201c\u304d\u3057\u307f\u201d\u3084\u201c\u4e7e\u71e5\u611f\u201d\u3092\u548c\u3089\u3052\u3001\u6d17\u3044\u4e0a\u304c\u308a\u306e\u306a\u3081\u3089\u304b\u3055\uff08\u30b3\u30f3\u30c7\u30a3\u30b7\u30e7\u30cb\u30f3\u30b0\uff09\u3092\u88dc\u52a9\u3059\u308b\u6210\u5206\u3068\u3057\u3066\u8aac\u660e\u3067\u304d\u308b\u3002
\r\n\r\n\u30105\u3011Latini V, et al.Application Possibilities of Sustainable Nanostructured Silica-Based Materials in Cosmetics.Cosmetics (Basel). 2025;12(4):134.<\/a><\/cite>
\r\n\r\nDOI: 10.3390\/cosmetics12040134
\r\n\r\n\u65e5\u672c\u8a9e\u8981\u65e8\uff1a<\/strong>\u30b7\u30ea\u30ab\u7cfb\u6750\u6599\uff08\u591a\u5b54\u8cea\u30b7\u30ea\u30ab\u3001\u30ca\u30ce\u69cb\u9020\u30b7\u30ea\u30ab\u7b49\uff09\u306e\u5316\u7ca7\u54c1\u5fdc\u7528\u3092\u307e\u3068\u3081\u305f\u30ec\u30d3\u30e5\u30fc\u3002\u30b7\u30ea\u30ab\u306f\u5927\u304d\u306a\u6bd4\u8868\u9762\u7a4d\u3092\u6301\u3061\u3001\u76ae\u8102\u30fb\u6cb9\u5206\u306e\u5438\u7740\u3084\u3001\u88fd\u5264\u306e\u5b89\u5b9a\u5316\u3001\u4f7f\u7528\u611f\uff08\u3055\u3089\u3055\u3089\u611f\u30fb\u3059\u3079\u308a\uff09\u8abf\u6574\u306a\u3069\u306e\u88dc\u52a9\u6a5f\u80fd\u3092\u62c5\u3046\u3002\u6d17\u9854\u5264\u3067\u306f\u3001\u904e\u5270\u306a\u76ae\u8102\u306b\u3088\u308b\u30d9\u30bf\u3064\u304d\u3084\u6bdb\u7a74\u5468\u308a\u306e\u4e0d\u5feb\u611f\u306b\u5bfe\u3057\u3066\u3001\u201c\u76ae\u8102\u3092\u53d6\u308a\u3059\u304e\u305a\u306b\u5438\u7740\u3057\u3066\u6574\u3048\u308b\u201d\u8a2d\u8a08\u306e\u7406\u8ad6\u80cc\u666f\u3068\u306a\u308b\u3002
\r\n\r\n\u30106\u3011Fiume MM, Bergfeld WF, Belsito DV, et al.Safety Assessment of Talc as Used in Cosmetics.Int J Toxicol. 2015;34(1 Suppl):66S\u2013129S.<\/a>
\r\n\r\n<\/cite>PMID: 26227892 DOI: 10.1177\/1091581815586797
\r\n\r\n\u65e5\u672c\u8a9e\u8981\u65e8\uff1a<\/strong>\u5316\u7ca7\u54c1\u6210\u5206\u3068\u3057\u3066\u4f7f\u7528\u3055\u308c\u308b\u30bf\u30eb\u30af\u306b\u3064\u3044\u3066\u3001\u6bd2\u6027\u30fb\u523a\u6fc0\u6027\u7b49\u306e\u30c7\u30fc\u30bf\u3092\u7dcf\u5408\u8a55\u4fa1\u3057\u305f\u5b89\u5168\u6027\u30ec\u30d3\u30e5\u30fc\uff08CIR\u95a2\u9023\uff09\u3002\u5316\u7ca7\u54c1\u30b0\u30ec\u30fc\u30c9\u306e\u30bf\u30eb\u30af\u306f\u30a2\u30b9\u30d9\u30b9\u30c8\u3092\u542b\u307e\u306a\u3044\u7ba1\u7406\u304c\u524d\u63d0\u3067\u3042\u308a\u3001\u73fe\u884c\u306e\u4f7f\u7528\u5b9f\u614b\u30fb\u914d\u5408\u6fc3\u5ea6\u306b\u304a\u3044\u3066\u5b89\u5168\u6027\u304c\u652f\u6301\u3055\u308c\u308b\u3068\u7d50\u8ad6\u3002\u6d17\u9854\u5264\u306b\u914d\u5408\u3055\u308c\u308b\u5834\u5408\u306f\u3001\u4e3b\u306b\u611f\u89e6\uff08\u3059\u3079\u308a\uff09\u30fb\u5206\u6563\u6027\u30fb\u4f7f\u7528\u611f\u306e\u8abf\u6574\u306a\u3069\u88dc\u52a9\u7684\u5f79\u5272\u3068\u3057\u3066\u8aac\u660e\u3067\u304d\u3001\u540c\u6642\u306b\u201c\u5b89\u5168\u6027\u8a55\u4fa1\u306e\u6839\u62e0\u201d\u3068\u306a\u308b\u3002
\r\n\r\n\u30107\u3011Papain <\/a><\/cite>
\r\n\r\n\u65e5\u672c\u8a9e\u8981\u65e8\uff08\u4e00\u822c\u77e5\u8b58\u4ed8\uff09:<\/strong>\u30d1\u30d1\u30a4\u30f3\u306f\u30d1\u30d1\u30a4\u30e4\u7531\u6765\u306e\u30b7\u30b9\u30c6\u30a4\u30f3\u30d7\u30ed\u30c6\u30a2\u30fc\u30bc\u3067\u3042\u308a\u3001\u5316\u7ca7\u54c1\u30fb\u6d17\u6d44\u6599\u306e\u6210\u5206\u3068\u3057\u3066\u30bf\u30f3\u30d1\u30af\u8cea\u5206\u89e3\u4f5c\u7528\u3092\u6301\u3064\u9175\u7d20\u3067\u3042\u308b\u3053\u3068\u304c\u78ba\u8a8d\u3055\u308c\u3066\u3044\u308b\u3002\u5316\u7ca7\u54c1\u8a2d\u8a08\u6642\u306b\u306f\u305d\u306e\u6d3b\u6027\u7279\u6027\u3068\u5b89\u5168\u6027\u3092\u8003\u616e\u3059\u308b\u5fc5\u8981\u304c\u3042\u308b\u3002
\r\n\r\n<\/pre>\n
 <\/p>\n
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\u8457\u4f5c\uff08\u5171\u8457\uff09<\/p>\n
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\n\u305d\u306e\u6642\u671f\u306b\u5408\u3063\u305f\u30b9\u30ad\u30f3\u30b1\u30a2\u3084\u30a8\u30a4\u30b8\u30f3\u30b0\u30b1\u30a2\u306e\u304a\u5f79\u7acb\u3061\u60c5\u5831\u3092\u30e1\u30fc\u30eb\u3067\u30b3\u30f3\u30d1\u30af\u30c8\u306b\u304a\u5c4a\u3051\u3057\u3066\u3044\u307e\u3059\u3002
\n\u305c\u3072\u3054\u767b\u9332\u3092\u304a\u5f85\u3061\u3057\u3066\u304a\u308a\u307e\u3059\u3002<\/p>\n
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