{"id":68026,"date":"2026-01-22T12:44:50","date_gmt":"2026-01-22T03:44:50","guid":{"rendered":"https:\/\/www.nahls.co.jp\/eijingukea\/?p=68026"},"modified":"2026-01-22T15:29:09","modified_gmt":"2026-01-22T06:29:09","slug":"nahls-pure_kie","status":"publish","type":"post","link":"https:\/\/www.nahls.co.jp\/eijingukea\/evidences\/hiroba\/nahls-pure_kie\/","title":{"rendered":"\u30ca\u30fc\u30eb\u30b9\u30d4\u30e5\u30a2\u304c\u30ea\u30cb\u30e5\u30fc\u30a2\u30eb\u3057\u30661\u5e74\u3002\u4f7f\u3063\u305f\u611f\u60f3\u3002by KIE"},"content":{"rendered":"
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2020\u5e7411\u67086\u65e5\uff08\u91d1\uff09\u306b\u3001\u30ea\u30cb\u30e5\u30fc\u30a2\u30eb\u8ca9\u58f2\u3057\u3001\u4f55\u304c\u5909\u308f\u3063\u305f\u304b\u3068\u3044\u3046\u3068\u30fb\u30fb\u30fb\u30fb<\/p>\n
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\u808c\u306e\u89d2\u8cea\u3067\u8a00\u3048\u3070\u3001\u5929\u7136\u4fdd\u6e7f\u56e0\u5b50\u3068\u4f3c\u305f\u306f\u305f\u3089\u304d\u3092\u767a\u63ee\u3057\u307e\u3059\u3002<\/p>\n \u3057\u304b\u3057\u3001\u6c34\u5206\u306e\u84b8\u6563\u3092\u9632\u3052\u306a\u3044\u306e\u3067\u3059\u3002<\/p>\n \u3060\u304b\u3089\u3001\u6e7f\u5ea6\u304c\u4f4e\u304f\u4e7e\u71e5\u3057\u3084\u3059\u3044\u5b63\u7bc0\u306b\u306f\u3001\u5316\u7ca7\u6c34\u3060\u3051\u306e\u30b1\u30a2\u306f\u4e7e\u71e5\u808c\u306e\u30ea\u30b9\u30af\u304c\u9ad8\u304f\u306a\u308a\u307e\u3059\u3002<\/p>\n \u51ac\u5834\u306f\u3001\u5316\u7ca7\u6c34\u3060\u3051\u306b\u983c\u3089\u305a\u3001\u307b\u304b\u306e\u30a2\u30a4\u30c6\u30e0\u3082\u4f7f\u3063\u3066\u30a8\u30a4\u30b8\u30f3\u30b0\u30b1\u30a2\u3092\u3059\u308b\u3053\u3068\u304c\u304a\u3059\u3059\u3081\u3067\u3059\u3002<\/p>\n \u305f\u3068\u3048\u3070\u3001\u30d2\u30c8\u578b\u30bb\u30e9\u30df\u30c9\u914d\u5408\u306e\u7f8e\u5bb9\u6db2\u3084\u30b7\u30a2\u30d0\u30bf\u30fc\u3084\u30b9\u30af\u30ef\u30e9\u30f3\u306a\u3069\u6cb9\u6027\u306e\u30a8\u30e2\u30ea\u30a8\u30f3\u30c8\u6210\u5206\u3092\u542b\u3080\u4fdd\u6e7f\u30af\u30ea\u30fc\u30e0\u3067\u3001\u3057\u3063\u304b\u308a\u4fdd\u6e7f\u30b1\u30a2\u3092\u3059\u308b\u3053\u3068\u304c\u5927\u5207\u3067\u3059\u3002<\/p>\n \u30a8\u30e2\u30ea\u30a8\u30f3\u30c8\u6210\u5206\u306f\u76ae\u8102\u819c\u3068\u4f3c\u305f\u306f\u305f\u3089\u304d\u3067\u3001\u6c34\u5206\u306e\u84b8\u6563\u3092\u9632\u304e\u307e\u3059\u3002<\/p>\n \u307e\u305f\u300130\u4ee3\u4ee5\u4e0a\u306e\u30a8\u30a4\u30b8\u30f3\u30b0\u30b1\u30a2\u4e16\u4ee3\u306e\u65b9\u306f\u3001\u51ac\u3082\u4e7e\u71e5\u808c\u5bfe\u7b56\u306b\u52a0\u3048\u3066\u30a8\u30a4\u30b8\u30f3\u30b0\u30b1\u30a2\u3092\u610f\u8b58\u3059\u308b\u3053\u3068\u304c\u5927\u5207\u3067\u3059\u3002<\/p>\n \u4fdd\u6e7f\u6210\u5206\u306b\u52a0\u3048\u3066\u3001\u30d3\u30bf\u30df\u30f3C\u8a98\u5c0e\u4f53\u3001\u30ca\u30fc\u30eb\u30b9\u30b2\u30f3\u3001\u30d3\u30bf\u30df\u30f3E\u8a98\u5c0e\u4f53\u3001\u30b3\u30a8\u30f3\u30b6\u30a4\u30e0Q10\u306a\u3069\u306e\u30a8\u30a4\u30b8\u30f3\u30b0\u30b1\u30a2\u304c\u3067\u304d\u308b\u6210\u5206\u3001\u9178\u5316\u3092\u9632\u3050\u6210\u5206\u304c\u5165\u3063\u305f\u30b9\u30ad\u30f3\u30b1\u30a2\u30a2\u30a4\u30c6\u30e0\u3092\u9078\u3073\u307e\u3057\u3087\u3046\u3002<\/p>\n \uff1c\u53c2\u8003\u8a18\u4e8b\uff1e<\/p>\n \uff0a\u51ac\u306b\u5316\u7ca7\u6c34\u306f\u5909\u3048\u308b\uff1f\u30a8\u30a4\u30b8\u30f3\u30b0\u30b1\u30a2\u7684\u9078\u3073\u65b9\u3068\u4f7f\u3044\u65b9<\/a><\/p>\n KIE\u3055\u3093\u3001\u30a8\u30a4\u30b8\u30f3\u30b0\u30b1\u30a2\u5316\u7ca7\u6c34\u300c\u30ca\u30fc\u30eb\u30b9\u30d4\u30e5\u30a2\u300d\u306e\u8a18\u4e8b\u306e\u5fa1\u57f7\u7b46\u3042\u308a\u304c\u3068\u3046\u3054\u3056\u3044\u307e\u3057\u305f\u3002<\/p>\n \u30ca\u30fc\u30eb\u30b9\u30d4\u30e5\u30a2\u306f\u6628\u5e74\u306b2\u5ea6\u76ee\u306e\u30ea\u30cb\u30e5\u30fc\u30a2\u30eb\u3092\u3057\u3066\u3044\u307e\u3059\u304c\u3001\u30ca\u30fc\u30eb\u30b9\u30b2\u30f3\u63a8\u5968\u6fc3\u5ea6\u914d\u5408\u306f\u305d\u306e\u307e\u307e\u3067\u3001\u3055\u3089\u306b\u30a8\u30a4\u30b8\u30f3\u30b0\u30b1\u30a2\u306b\u826f\u3044\u7f8e\u5bb9\u6210\u5206\u3092\u8ffd\u52a0\u3057\u9032\u5316\u3057\u3066\u304a\u308a\u307e\u3059\u3002<\/p>\n KIE\u3055\u3093\u3082\u30ea\u30cb\u30e5\u30fc\u30a2\u30eb\u3057\u305f\u30ca\u30fc\u30eb\u30b9\u30d4\u30e5\u30a2\u3092\u3042\u3089\u305f\u3081\u3066\u3054\u4f7f\u7528\u3044\u305f\u3060\u304d\u3001\u808c\u306e\u6f64\u3044\u3092\u3057\u3063\u304b\u308a\u5b9f\u611f\u3057\u3066\u9802\u3051\u305f\u3088\u3046\u3067\u826f\u304b\u3063\u305f\u3067\u3059\u3002<\/p>\n KIE\u3055\u3093\u306e\u8a18\u4e8b\u300c\u30ca\u30fc\u30eb\u30b9\u30d4\u30e5\u30a2\u304c\u30ea\u30cb\u30e5\u30fc\u30a2\u30eb\u3057\u30661\u5e74\u3002\u4f7f\u3063\u305f\u611f\u60f3\u3002by KIE\u300d\u304c\u30ca\u30fc\u30eb\u30b9\u30a8\u30a4\u30b8\u30f3\u30b0\u30b1\u30a2\u30a2\u30ab\u30c7\u30df\u30fc\u306e\u8aad\u8005\u306e\u307f\u306a\u3055\u307e\u306e\u304a\u5f79\u306b\u7acb\u3064\u3053\u3068\u3092\u9858\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n <\/p>\n <\/p>\n \uff08\u7de8\u96c6\u30fb\u6821\u6b63\uff1a\u682a\u5f0f\u4f1a\u793e\u30c7\u30a3\u30fc\u30d7\u30a4\u30f3\u30d1\u30af\u30c8\u3000\u4ee3\u8868\u53d6\u7de0\u5f79\u3000\u5bcc\u672c\u5145\u662d\uff09<\/p>\n \u30ca\u30fc\u30eb\u30b9\u30a8\u30a4\u30b8\u30f3\u30b0\u30b1\u30a2\u30a2\u30ab\u30c7\u30df\u30fc\u7de8\u96c6\u9577<\/a><\/p>\n \u4eac\u90fd\u5927\u5b66\u8fb2\u5b66\u90e8\u3092\u5352\u696d\u5f8c\u3001\u88fd\u85ac\u4f01\u696d\u306b7\u5e74\u9593\u52e4\u52d9\u306e\u5f8c\u3001\u533b\u5b66\u51fa\u7248\u793e\u3001\u533b\u5b66\u7cfb\u5e83\u544a\u4ee3\u7406\u5e97\u52e4\u52d9\u306e\u5f8c\u3001\u73fe\u8077\u306b\u81f3\u308b\u3002<\/p>\n \u533b\u85ac\u54c1\u306e\u958b\u767a\u652f\u63f4\u696d\u52d9\u3001\u533b\u5b66\u7cfb\u5b66\u4f1a\u306e\u53d6\u6750\u3084\u8a18\u4e8b\u57f7\u7b46\u3001\u533b\u85ac\u54c1\u30de\u30fc\u30b1\u30c6\u30a3\u30f3\u30b0\u95a2\u9023\u306e\u30bb\u30df\u30ca\u30fc\u8b1b\u5e2b\u306a\u3069\u3092\u884c\u3046\u3002<\/p>\n \u6587\u90e8\u79d1\u5b66\u7701\u5f8c\u63f4\u65e5\u672c\u5316\u7ca7\u54c1\u691c\u5b9a1\u7d1a<\/a>\u3002<\/p>\n \u4e00\u822c\u793e\u56e3\u6cd5\u4eba\u5316\u7ca7\u54c1\u6210\u5206\u691c\u5b9a\u5354\u4f1a\u8a8d\u5b9a\u5316\u7ca7\u54c1\u6210\u5206\u4e0a\u7d1a\u30b9\u30da\u30b7\u30e3\u30ea\u30b9\u30c8<\/a><\/p>\n \u8457\u4f5c\uff08\u5171\u8457\uff09<\/p>\n \uff2b\uff2f\uff2c\u30c9\u30af\u30bf\u30fc\u306e\u7684\u78ba\u306a\u4eba\u9078\u3068\u826f\u597d\u306a\u95a2\u4fc2\u4f5c\u308a\u306e\u30b3\u30c4<\/a><\/p>\n \u533b\u85ac\u54c1\u30de\u30fc\u30b1\u30c6\u30a3\u30f3\u30b0\u306b\u304a\u3051\u308b\u5e02\u5834\u30fb\u58f2\u4e0a\u4e88\u6e2c\u3068\u6226\u7565\u7b56\u5b9a<\/a><\/p>\n<\/div>\n<\/div>\n \u5f53\u793e\u30b9\u30bf\u30c3\u30d5\u306e\u672c\u696d\u306f\u3001\u533b\u5b66\u30fb\u85ac\u5b66\u95a2\u9023\u306e\u4e8b\u696d\u306e\u305f\u3081\u3001\u65e5\u3005\u3001\u533b\u5b66\u8ad6\u6587\u3084\u533b\u5b66\u4f1a\u306e\u767a\u8868\u306a\u3069\u306e\u6700\u65b0\u60c5\u5831\u306b\u89e6\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n \u305d\u3093\u306a\u4e2d\u3067\u3001\u300c\u3053\u308c\u306f\uff01\u300d\u3068\u3044\u3046\u3001\u307f\u306a\u3055\u307e\u306e\u5065\u5eb7\u3065\u304f\u308a\u306e\u3054\u53c2\u8003\u306b\u306a\u308b\u3088\u3046\u306a\u60c5\u5831\u3054\u7d39\u4ecb\u3057\u305f\u308a\u3001\u305d\u306e\u6642\u671f\u306b\u5408\u3063\u305f\u30b9\u30ad\u30f3\u30b1\u30a2\u3084\u30a8\u30a4\u30b8\u30f3\u30b0\u30b1\u30a2\u306e\u304a\u5f79\u7acb\u3061\u60c5\u5831\u3092\u30e1\u30fc\u30eb\u3067\u30b3\u30f3\u30d1\u30af\u30c8\u306b\u304a\u5c4a\u3051\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n \u305c\u3072\u3054\u767b\u9332\u3092\u304a\u5f85\u3061\u3057\u3066\u304a\u308a\u307e\u3059\u3002<\/p>\n
<\/a><\/p>\n2\uff0e\u8ffd\u52a0\u3055\u308c\u305f3\u3064\u306e\u6210\u5206\u306f\u3053\u3061\u3089<\/h2>\n
<\/a><\/p>\n3\uff0e\u4f7f\u3063\u3066\u307f\u305f\u611f\u60f3<\/h2>\n
4\uff0e\u51ac\u306b\u304a\u3059\u3059\u3081\u306e\u5316\u7ca7\u6c34\u3063\u3066\uff1f\uff08\u30ca\u30fc\u30eb\u30b9\u30a8\u30a4\u30b8\u30f3\u30b0\u30b1\u30a2\u30a2\u30ab\u30c7\u30df\u30fc\u7de8\u96c6\u90e8\uff09<\/h2>\n
5\uff0e\u30ca\u30fc\u30eb\u30b9\u30a8\u30a4\u30b8\u30f3\u30b0\u30b1\u30a2\u30a2\u30ab\u30c7\u30df\u30fc\u7de8\u96c6\u90e8\u30b3\u30e1\u30f3\u30c8<\/h2>\n
\uff1c\u53c2\u7167\u8ad6\u6587\uff1e<\/h2>\n
\r\n\u30101\u3011Bissett DL, Oblong JE, Berge CA. Niacinamide: A B vitamin that improves aging facial skin appearance. Dermatologic Surgery. 2005;31(7 Pt 2):860\u2013865.<\/a><\/cite>
\r\nPMID: 16029679\uff5cDOI: 10.1111\/j.1524-4725.2005.31726
\r\n\r\n\u65e5\u672c\u8a9e\u8981\u65e8\uff1a<\/strong>\u30ca\u30a4\u30a2\u30b7\u30f3\u30a2\u30df\u30c9\u5916\u7528\u306b\u3088\u308a\u3001\u5c0f\u3058\u308f\u3001\u8272\u30e0\u30e9\u3001\u9ec4\u3050\u3059\u307f\u306e\u6539\u5584\u3068\u3068\u3082\u306b\u3001\u89d2\u8cea\u30d0\u30ea\u30a2\u6a5f\u80fd\u306e\u5411\u4e0a\u304c\u81e8\u5e8a\u7684\u306b\u793a\u3055\u308c\u305f\u7814\u7a76\u3067\u3042\u308b\u3002\u708e\u75c7\u6291\u5236\u3084\u30bb\u30e9\u30df\u30c9\u5408\u6210\u4fc3\u9032\u306a\u3069\u3001\u5e74\u9f62\u808c\u306e\u8cea\u611f\u6539\u5584\u52b9\u679c\u304c\u78ba\u8a8d\u3055\u308c\u3066\u3044\u308b\u3002\u672c\u7814\u7a76\u306f\u3001\u30ca\u30fc\u30eb\u30b9\u30d4\u30e5\u30a2\u306b\u914d\u5408\u3055\u308c\u3066\u3044\u308b\u30ca\u30a4\u30a2\u30b7\u30f3\u30a2\u30df\u30c9\u304c\u3001\u808c\u306e\u30d0\u30ea\u30a2\u6a5f\u80fd\u3092\u6574\u3048\u308b\u3053\u3068\u3067\u9577\u671f\u4f7f\u7528\u3067\u306e\u808c\u30b3\u30f3\u30c7\u30a3\u30b7\u30e7\u30f3\u5411\u4e0a\u306b\u5bc4\u4e0e\u3059\u308b\u7406\u7531\u3092\u88cf\u4ed8\u3051\u308b\u6839\u62e0\u3068\u306a\u308b\u3002
\r\n\r\n\u30102\u3011Pullar JM, Carr AC, Vissers MCM. The Roles of Vitamin C in Skin Health. Nutrients. 2017;9(8):866.<\/a><\/cite>
\r\n\r\nPMID: 28805671\uff5cDOI: 10.3390\/nu9080866
\r\n\r\n\u65e5\u672c\u8a9e\u8981\u65e8\uff1a<\/strong>\u30d3\u30bf\u30df\u30f3C\u306f\u3001\u30b3\u30e9\u30fc\u30b2\u30f3\u5408\u6210\u4fc3\u9032\u3001\u6297\u9178\u5316\u4f5c\u7528\u3001\u30e1\u30e9\u30cb\u30f3\u751f\u6210\u6291\u5236\u306b\u95a2\u4e0e\u3059\u308b\u76ae\u819a\u6210\u5206\u3068\u3057\u3066\u6ce8\u76ee\u3055\u308c\u3066\u3044\u308b\u3002\u672c\u7dcf\u8aac\u306f\u3053\u308c\u3089\u306e\u4f5c\u7528\u3092\u5206\u5b50\u30ec\u30d9\u30eb\u3067\u6574\u7406\u3057\u3066\u304a\u308a\u3001\u30d3\u30bf\u30df\u30f3C\u8a98\u5c0e\u4f53\u3092\u542b\u3080\u30ca\u30fc\u30eb\u30b9\u30d4\u30e5\u30a2\u304c\u900f\u660e\u611f\u3084\u30cf\u30ea\u611f\u306e\u6539\u5584\u306b\u5bc4\u4e0e\u3059\u308b\u79d1\u5b66\u7684\u80cc\u666f\u3092\u88dc\u5f37\u3059\u308b\u3002
\r\n\r\n\u30103\u3011Rawlings AV, Harding CR. Moisturization and skin barrier function. Dermatologic Therapy. 2004;17(Suppl 1):43\u201348.<\/a><\/cite>
\r\n\r\nPMID: 14728698\uff5cDOI: 10.1111\/j.1396-0296.2004.04s1005.x
\r\n\r\n\u65e5\u672c\u8a9e\u8981\u65e8\uff1a<\/strong>\u89d2\u8cea\u5c64\u306e\u6c34\u5206\u4fdd\u6301\u6a5f\u80fd\u3068\u30d0\u30ea\u30a2\u6a5f\u80fd\u306e\u95a2\u4fc2\u3092\u89e3\u8aac\u3057\u305f\u7dcf\u8aac\u3067\u3001NMF\uff08\u5929\u7136\u4fdd\u6e7f\u56e0\u5b50\uff09\u3084\u7d30\u80de\u9593\u8102\u8cea\u304c\u6c34\u5206\u4fdd\u6301\u306b\u91cd\u8981\u3067\u3042\u308b\u3053\u3068\u3092\u793a\u3057\u3066\u3044\u308b\u3002\u672c\u8ad6\u6587\u306f\u3001PCA-Na\u7b49\u306e\u4fdd\u6e7f\u6210\u5206\u3092\u542b\u3080\u30ca\u30fc\u30eb\u30b9\u30d4\u30e5\u30a2\u304c\u3001\u51ac\u306e\u4e7e\u71e5\u3067\u3082\u6f64\u3044\u3092\u4fdd\u3061\u3084\u3059\u3044\u7406\u7531\u3092\u7406\u8ad6\u7684\u306b\u8aac\u660e\u3059\u308b\u30a8\u30d3\u30c7\u30f3\u30b9\u3068\u306a\u308b\u3002
\r\n\r\n\u30104\u3011Draelos ZD. The science behind skin care: Moisturizers. Journal of Cosmetic Dermatology. 2018;17(2):138\u2013144.<\/a><\/cite>
\r\n\r\nPMID: 29319217\uff5cDOI: 10.1111\/jocd.12490
\r\n\r\n\u65e5\u672c\u8a9e\u8981\u65e8\uff1a<\/strong>\u30d2\u30e5\u30fc\u30e1\u30af\u30bf\u30f3\u30c8\uff08\u4fdd\u6e7f\u56e0\u5b50\uff09\u3001\u30a8\u30e2\u30ea\u30a8\u30f3\u30c8\uff08\u67d4\u8edf\u5316\u5264\uff09\u3001\u30aa\u30af\u30eb\u30fc\u30b7\u30d6\uff08\u9589\u585e\u5264\uff09\u306a\u3069\u306e\u4f5c\u7528\u6a5f\u5e8f\u3092\u6574\u7406\u3057\u305f\u7dcf\u8aac\u3002\u4f4e\u523a\u6fc0\u304b\u3064\u9ad8\u4fdd\u6e7f\u8a2d\u8a08\u306e\u30ca\u30fc\u30eb\u30b9\u30d4\u30e5\u30a2\u304c\u3001\u4e7e\u71e5\u3057\u3084\u3059\u3044\u5b63\u7bc0\u3067\u3082\u6bce\u65e5\u7d9a\u3051\u3089\u308c\u308b\u5316\u7ca7\u6c34\u3067\u3042\u308b\u3053\u3068\u3092\u652f\u6301\u3059\u308b\u3002
\r\n\r\n\u30105\u3011Verdier-S\u00e9vrain S, Bont\u00e9 F. Skin hydration: a review on its molecular mechanisms. Journal of Cosmetic Dermatology. 2007;6(2):75\u201382.<\/a><\/cite>
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\r\n\r\n\u65e5\u672c\u8a9e\u8981\u65e8\uff1a<\/strong>\u76ae\u819a\u306e\u3046\u308b\u304a\u3044\u306f\u89d2\u8cea\u69cb\u9020\u3001NMF\u3001\u7d30\u80de\u9593\u8102\u8cea\u3001\u6c34\u5206\u79fb\u52d5\u304c\u9023\u52d5\u3057\u3066\u7dad\u6301\u3055\u308c\u308b\u3068\u307e\u3068\u3081\u305f\u7dcf\u8aac\u3002\u30ca\u30fc\u30eb\u30b9\u30d4\u30e5\u30a2\u306e\u6f64\u3044\u5b9f\u611f\u304c\u3001\u89d2\u8cea\u5c64\u306e\u4fdd\u6c34\u6a5f\u80fd\u3092\u652f\u3048\u308b\u8981\u7d20\u3092\u88dc\u3046\u3068\u3044\u3046\u76ae\u819a\u79d1\u5b66\u7684\u6839\u62e0\u3092\u793a\u3059\u3002
\r\n\r\n\u30106\u3011Robinson LR, Fitzgerald NC, Doughty DG, Dawes NC, Berge CA, Bissett DL. Topical palmitoyl pentapeptide provides improvement in photoaged human facial skin. International Journal of Cosmetic Science. 2005;27(3):155\u2013160.<\/a><\/cite>
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\r\n\r\n\u65e5\u672c\u8a9e\u8981\u65e8\uff1a<\/strong>\u30b7\u30b0\u30ca\u30eb\u30da\u30d7\u30c1\u30c9\uff08Pal-KTTKS\uff09\u5916\u7528\u3067\u5149\u8001\u5316\u306b\u4f34\u3046\u5c0f\u3058\u308f\u306e\u6539\u5584\u304c\u8a8d\u3081\u3089\u308c\u305f\u81e8\u5e8a\u7814\u7a76\u3002\u672c\u7814\u7a76\u306f\u3001\u30da\u30d7\u30c1\u30c9\u7cfb\u6210\u5206\u306a\u3069\u304c\u8907\u5408\u3055\u308c\u305f\u5316\u7ca7\u6c34\u304c\u3001\u30cf\u30ea\u611f\u3084\u808c\u8cea\u306e\u6539\u5584\u306b\u5bc4\u4e0e\u3059\u308b\u53ef\u80fd\u6027\u3092\u793a\u3059\u79d1\u5b66\u7684\u80cc\u666f\u3068\u3057\u3066\u5f15\u7528\u3067\u304d\u308b\u3002
\r\n\r\n\u30107\u3011Bai X-D, Liu Y-C, Ge S-Y, Fei W-C. Clinical Trial of Salmon Nasal Cartilage-Derived Proteoglycans on Human Facial Antiaging. Journal of Cosmetic Dermatology. 2025;24(7):e70218.<\/a><\/cite>
\r\n\r\nPMID: 40613544\uff5cDOI: 10.1111\/jocd.70218
\r\n\r\n\u65e5\u672c\u8a9e\u8981\u65e8\uff1a<\/strong>\u30b5\u30b1\u9f3b\u8edf\u9aa8\u7531\u6765\u30d7\u30ed\u30c6\u30aa\u30b0\u30ea\u30ab\u30f3\u306b\u3064\u3044\u3066\u3001\u808c\u6c34\u5206\u91cf\u30fb\u5f3e\u529b\u30fb\u8cea\u611f\u306e\u6539\u5584\u304c\u78ba\u8a8d\u3055\u308c\u305fRCT\u3002\u30d7\u30ed\u30c6\u30aa\u30b0\u30ea\u30ab\u30f3\u914d\u5408\u306e\u30ca\u30fc\u30eb\u30b9\u30d4\u30e5\u30a2\u304c\u9577\u671f\u4f7f\u7528\u3067\u808c\u30b3\u30f3\u30c7\u30a3\u30b7\u30e7\u30f3\u3092\u5e95\u4e0a\u3052\u3059\u308b\u6839\u62e0\u3068\u3057\u3066\u4f7f\u3048\u308b\u3002
\r\n\r\n\u30108\u3011Engebretsen KA, Johansen JD, Kezic S, Linneberg A, Thyssen JP. The effect of environmental humidity and temperature on skin barrier function and dermatitis. J Eur Acad Dermatol Venereol. 2016;30(2):223\u201349.<\/a><\/cite>
\r\n\r\nPMID: 26449379\uff5cDOI: 10.1111\/jdv.13301
\r\n\r\n\u65e5\u672c\u8a9e\u8981\u65e8\uff1a<\/strong>\u4f4e\u6e7f\u5ea6\u30fb\u4f4e\u6c17\u6e29\u3068\u3044\u3046\u51ac\u306e\u6c17\u5019\u6761\u4ef6\u304c\u89d2\u8cea\u30d0\u30ea\u30a2\u6a5f\u80fd\u3092\u4f4e\u4e0b\u3055\u305b\u3001\u76ae\u819a\u306e\u4e7e\u71e5\u3084\u523a\u6fc0\u3078\u306e\u611f\u53d7\u6027\u3092\u9ad8\u3081\u308b\u3068\u3044\u3046\u30e1\u30ab\u30cb\u30ba\u30e0\u3092\u30ec\u30d3\u30e5\u30fc\u3057\u305f\u8ad6\u6587\u3067\u3042\u308b\u3002\u7279\u306b\u3001\u51ac\u5b63\u306b\u304a\u3051\u308b\u6e7f\u5ea6\u30fb\u6c17\u6e29\u306e\u5909\u5316\u304c\u76ae\u819a\u30d0\u30ea\u30a2\u6a5f\u80fd\u3092\u640d\u306a\u3044\u3084\u3059\u3044\u3053\u3068\u3092\u793a\u3057\u3001\u4e7e\u71e5\u5bfe\u7b56\u3068\u3057\u3066\u4fdd\u6e7f\u3084\u30d0\u30ea\u30a2\u5f37\u5316\u8a2d\u8a08\u306e\u30ca\u30fc\u30eb\u30b9\u30d4\u30e5\u30a2\u306e\u3088\u3046\u306a\u30a8\u30a4\u30b8\u30f3\u30b0\u30b1\u30a2\u5316\u7ca7\u6c34\u306e\u9078\u629e\u304c\u7406\u306b\u304b\u306a\u3063\u3066\u3044\u308b\u3053\u3068\u3092\u652f\u6301\u3059\u308b\u3002\r\n\r\n\r\n<\/pre>\n\u8457\u8005\u30fb\u7de8\u96c6\u8005\u30fb\u6821\u6b63\u8005\u60c5\u5831<\/h2>\n<\/div>\n
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