{"id":68587,"date":"2026-01-05T09:30:43","date_gmt":"2026-01-05T00:30:43","guid":{"rendered":"https:\/\/www.nahls.co.jp\/eijingukea\/?p=68587"},"modified":"2026-01-06T09:46:50","modified_gmt":"2026-01-06T00:46:50","slug":"nahls-eyecare-nonmam","status":"publish","type":"post","link":"https:\/\/www.nahls.co.jp\/eijingukea\/evidences\/hiroba\/nahls-eyecare-nonmam\/","title":{"rendered":"\u30ca\u30fc\u30eb\u30b9\u306e\u30a2\u30a4\u30b1\u30a2\u30d5\u30a1\u30c3\u30b7\u30e7\u30f3\u30e1\u30ac\u30cd\u3067\u30a2\u30a4\u30b1\u30a2\u3092\u59cb\u3081\u307e\u3057\u3087\u3046\uff01 by \u306e\u3093mam"},"content":{"rendered":"
\n

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 <\/p>\n

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\n

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\n

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\n

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\"HEV\u306e\u56f3\"<\/a><\/p>\n

1\uff09\u30d6\u30eb\u30fc\u30e9\u30a4\u30c8<\/h3>\n

\u30d6\u30eb\u30fc\u30e9\u30a4\u30c8\u3068\u306f\u9752\u8272\u306e\u53ef\u8996\u5149\u7dda\u3067\u3059\u3002<\/p>\n

380\uff5e500nm\uff08\u30ca\u30ce\u30e1\u30fc\u30c8\u30eb\uff09\u3068\u6ce2\u9577\u304c\u77ed\u304f\u3001\u30a8\u30cd\u30eb\u30ae\u30fc\u304c\u5f37\u304f\u6563\u4e71\u3057\u3084\u3059\u3044\u7279\u5fb4\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n

\u30d6\u30eb\u30fc\u30e9\u30a4\u30c8\u306f\u3001\u592a\u967d\u5149\u7dda\u306b\u52a0\u3048\u3066\u3001\u30d1\u30bd\u30b3\u30f3\u3084\u30b9\u30de\u30fc\u30c8\u30d5\u30a9\u30f3\u306a\u3069\u306eLED\u30c7\u30a3\u30b9\u30d7\u30ec\u30a4\u306b\u591a\u304f\u542b\u307e\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n

\u30d6\u30eb\u30fc\u30e9\u30a4\u30c8\u306b\u306f\u3001\u671d\u6d74\u3073\u308b\u3068\u3001\u4f53\u5185\u6642\u8a08\u3068\u30b5\u30fc\u30ab\u30c7\u30a3\u30a2\u30f3\u30ea\u30ba\u30e0\u306e\u305a\u308c\u3092\u4fee\u6b63\u3057\u3001\u4f53\u5185\u30ea\u30ba\u30e0\u3092\u6574\u3048\u308b\u5065\u5eb7\u4e0a\u306e\u30e1\u30ea\u30c3\u30c8\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n

\u3057\u304b\u3057\u3001\u76ee\u306e\u75b2\u308c\u3084\u75db\u307f\u3001\u76ee\u306e\u8001\u5316\u3001\u52a0\u9f62\u9ec4\u6591\u5909\u6027\u75c7\u306e\u539f\u56e0\u306b\u306a\u308b\u5834\u5408\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n

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\u3055\u3089\u306b\u3001\u808c\u8001\u5316\u3084\u30b7\u30df\u306e\u539f\u56e0\u306b\u3082\u306a\u308b\u3068\u3044\u3046\u30c7\u30e1\u30ea\u30c3\u30c8\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n

\u30d6\u30eb\u30fc\u30e9\u30a4\u30c8\u306e\u5bfe\u7b56\u306b\u306f\u3001\u30d1\u30bd\u30b3\u30f3\u3084\u30b9\u30de\u30db\u3092\u9577\u6642\u9593\u898b\u3059\u304e\u306a\u3044\u3088\u3046\u306b\u3057\u305f\u308a\u3001\u30d6\u30eb\u30fc\u30e9\u30a4\u30c8\u3092\u30ab\u30c3\u30c8\u3059\u308b\u30e1\u30ac\u30cd\u3092\u304b\u3051\u308b\u65b9\u6cd5\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n

\u30ca\u30fc\u30eb\u30b9\u306e\u30a2\u30a4\u30b1\u30a2\u30e1\u30ac\u30cd\u3084\u65e5\u713c\u3051\u6b62\u3081\u306f\u3001\u30d6\u30eb\u30fc\u30e9\u30a4\u30c8\u306e\u30ab\u30c3\u30c8\u3082\u610f\u8b58\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n

\uff1c\u53c2\u8003\u8a18\u4e8b\uff1e<\/p>\n

\uff0a\u30d6\u30eb\u30fc\u30e9\u30a4\u30c8\u3092\u3046\u307e\u304f\u6d74\u3073\u3066\u30a2\u30f3\u30c1\u30a8\u30a4\u30b8\u30f3\u30b0\u3084\u5065\u5eb7\u306b\u5f79\u7acb\u3066\u3088\u3046\uff01<\/a><\/p>\n

\uff0a\u30c6\u30ec\u30ef\u30fc\u30af\u3067\u300e\u30c7\u30b8\u30bf\u30eb\u6642\u5dee\u30dc\u30b1\u300f\u5897\u52a0\uff01\u6539\u5584\u306b\u306f\u30d6\u30eb\u30fc\u30e9\u30a4\u30c8\u5bfe\u7b56<\/a><\/p>\n

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\u8d64\u3061\u3083\u3093\u3067\u3082\u4f7f\u3048\u308b\u307b\u3069\u512a\u3057\u304f\u3066\u3001\u3057\u3063\u304b\u308a\u7d2b\u5916\u7dda\u5bfe\u7b56\u304c\u3067\u304d\u308b\uff01<\/p>\n

\uff0aSPF50+\u30fbPA++++\u00a0\u00a0\u30ca\u30fc\u30eb\u30b9\u30b2\u30f3\u63a8\u5968\u6fc3\u5ea6\u914d\u5408UV\u5316\u7ca7\u4e0b\u5730\u300c\u30ca\u30fc\u30eb\u30b9 \u30f4\u30a7\u30fc\u30eb\u300d<\/a><\/p>\n

\"\u30a8\u30a4\u30b8\u30f3\u30b0\u30b1\u30a2\u4e16\u4ee3\u306b\u304a\u3059\u3059\u3081\u306e\u65e5\u713c\u3051\u6b62\u3081\uff06UV\u5316\u7ca7\u4e0b\u5730\u30ca\u30fc\u30eb\u30b9<\/a><\/p>\n

 <\/p>\n

2\uff09HEV<\/h3>\n

HEV\u3068\u306f\u3001High Energy Visible light\u306e\u7565\u3067\u3001\u65e5\u672c\u8a9e\u3067\u306f\u3001\u9ad8\u30a8\u30cd\u30eb\u30ae\u30fc\u53ef\u8996\u5149\u7dda\u3068\u547c\u3073\u307e\u3059\u3002<\/p>\n

HEV\u306f\u3001\u592a\u967d\u5149\u7dda\u306b\u542b\u307e\u308c\u308b400nm\uff5e420nm(\u30ca\u30ce\u30e1\u30fc\u30c8\u30eb)\u306e\u5e2f\u57df\u306e\u7d2b\u30fb\u9752\u8272\u306e\u5149\u3067\u3059\u3002<\/p>\n

\u53ef\u8996\u5149\u7dda\u3068\u3057\u3066\u77e5\u3089\u308c\u3066\u3044\u308b\u30d6\u30eb\u30fc\u30e9\u30a4\u30c8\u306f\u6ce2\u9577\u304c380\uff5e500nm\u3067\u3001HEV\u306f\u305d\u306e\u4e00\u90e8\u3067\u3059\u3002<\/p>\n

HEV\u304c\u76ee\u306e\u7db2\u819c\u306b\u3042\u308b\u300c\u9ec4\u6591\u300d\u3068\u3044\u3046\u90e8\u5206\u306b\u5f37\u3044\u30c0\u30e1\u30fc\u30b8\u3092\u4e0e\u3048\u3001\u76ee\u306e\u8001\u5316\u3092\u4fc3\u9032\u3059\u308b\u3053\u3068\u304c\u308f\u304b\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n

\u306a\u305c\u306a\u3089\u3001HEV\u306f\u6709\u5bb3\u5149\u7dda\u306e\u4e2d\u3067\u3082\u3001\u89d2\u819c\u3084\u6c34\u6676\u4f53\u3092\u900f\u904e\u3059\u308b\u5272\u5408\u304c\u9ad8\u3044\u305f\u3081\u7db2\u819c\u306b\u5c4a\u304d\u3084\u3059\u3044\u306e\u3067\u3059\u3002<\/p>\n

\u305d\u306e\u7d50\u679c\u3001\u767d\u5185\u969c\u3084\u52a0\u9f62\u9ec4\u6591\u5909\u6027\u75c7\u306e\u539f\u56e0\u306e1\u3064\u306b\u306a\u3063\u3066\u3057\u307e\u3046\u306e\u3067\u3059\u3002<\/p>\n

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\"\u30a2\u30a4\u30b1\u30a2\u30e1\u30ac\u30cd\"<\/a><\/p>\n

3\uff09\u8fd1\u8d64\u5916\u7dda<\/h3>\n

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<\u53c2\u8003\u8a18\u4e8b\uff1e<\/p>\n

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\n

5\uff0e\u30ca\u30fc\u30eb\u30b9\u30a8\u30a4\u30b8\u30f3\u30b0\u30b1\u30a2\u30a2\u30ab\u30c7\u30df\u30fc\u7de8\u96c6\u90e8\u30b3\u30e1\u30f3\u30c8\uff09<\/h2>\n

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\u306e\u3093mam\u3055\u3093\u3082\u6700\u8fd1\u82b1\u7c89\u75c7\u306b\u60a9\u307e\u3055\u308c\u308b\u3088\u3046\u306b\u306a\u3063\u305f\u3068\u306e\u4e8b\u3067\u3059\u304c\u3001\u30a2\u30a4\u30b1\u30a2\u30d5\u30a1\u30c3\u30b7\u30e7\u30f3\u30e1\u30ac\u30cd\u306f\u82b1\u7c89\u306f\u3082\u3061\u308d\u3093\u3001\u30a6\u30a3\u30eb\u30b9\u306e\u98db\u6cab\u306a\u3069\u3001\u7a7a\u6c17\u4e2d\u306e\u6709\u5bb3\u7269\u8cea\u304b\u3089\u3082\u76ee\u3092\u5b88\u3063\u3066\u304f\u308c\u307e\u3059\u3002<\/p>\n

\u307e\u3060\u307e\u3060\u7d9a\u304f\u82b1\u7c89\u306e\u5b63\u7bc0\u3084\u3001\u5f15\u304d\u7d9a\u304d\u30b3\u30ed\u30ca\u306a\u3069\u306b\u6c17\u3092\u3064\u3051\u306a\u3051\u308c\u3070\u3044\u3051\u306a\u3044\u4e16\u306e\u4e2d\u3067\u3001\u3053\u306e\u30b4\u30fc\u30b0\u30eb\u30bf\u30a4\u30d7\u306e\u30a2\u30a4\u30b1\u30a2\u30d5\u30a1\u30c3\u30b7\u30e7\u30f3\u30e1\u30ac\u30cd\u304c\u306e\u3093mam\u3055\u3093\u306e\u82b1\u7c89\u5bfe\u7b56\u3001\u30a6\u30a3\u30eb\u30b9\u5bfe\u7b56\u306a\u3069\u306b\u304a\u5f79\u306b\u7acb\u3066\u308b\u983c\u3082\u3057\u3044\u30a2\u30a4\u30c6\u30e0\u3068\u306a\u308c\u3070\u5b09\u3057\u304f\u601d\u3044\u307e\u3059\u3002<\/p>\n

\u7d2b\u5916\u7dda\u3082\u65e5\u3005\u304d\u3064\u304f\u306a\u3063\u3066\u304d\u307e\u3059\u304b\u3089\u3001\u305c\u3072\u30a2\u30a4\u30b1\u30a2\u30d5\u30a1\u30c3\u30b7\u30e7\u30f3\u30e1\u30ac\u30cd\u3067\u76ee\u3092\u5b88\u3063\u3066\u3044\u3063\u3066\u304f\u3060\u3055\u3044\u306d\u3002<\/p>\n

\u306e\u3093mam\u3055\u3093\u306e\u3053\u306e\u8a18\u4e8b\u300c\u30ca\u30fc\u30eb\u30b9\u306e\u30a2\u30a4\u30b1\u30a2\u30d5\u30a1\u30c3\u30b7\u30e7\u30f3\u30e1\u30ac\u30cd\u3067\u30a2\u30a4\u30b1\u30a2\u3092\u59cb\u3081\u307e\u3057\u3087\u3046\uff01by \u306e\u3093mam\u304c\u30ca\u30fc\u30eb\u30b9\u30a8\u30a4\u30b8\u30f3\u30b0\u30b1\u30a2\u30a2\u30ab\u30c7\u30df\u30fc\u306e\u8aad\u8005\u306e\u307f\u306a\u3055\u307e\u306e\u304a\u5f79\u306b\u7acb\u3064\u3053\u3068\u3092\u9858\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n

 <\/p>\n

\uff1c\u53c2\u7167\u8ad6\u6587\uff1e<\/h2>\n
\r\n\u30101\u3011Mahmoud BH, Hexsel CL, Hamzavi IH, Lim HW. Effects of visible light on the skin. Photochem Photobiol. 2008;84(2):450-462. <\/a><\/cite>
\r\n\r\nPMID: 18248499 DOI: 10.1111\/j.1751-1097.2007.002
\r\n\r\n\u65e5\u672c\u8a9e\u8981\u65e8:<\/strong>\u53ef\u8996\u5149\u7dda\u304c\u76ae\u819a\u306b\u4e0e\u3048\u308b\u5f71\u97ff\u3092\u5305\u62ec\u7684\u306b\u89e3\u8aac\u3057\u305f\u91cd\u8981\u6587\u732e\u3002HEV(\u9ad8\u30a8\u30cd\u30eb\u30ae\u30fc\u53ef\u8996\u5149\u7dda)\u304c\u7279\u306b\u8272\u7d20\u6c88\u7740\u3092\u5f15\u304d\u8d77\u3053\u3059\u3053\u3068\u3001UV\u5149\u7dda\u3068\u6bd4\u8f03\u3057\u3066\u30e1\u30e9\u30cb\u30f3\u751f\u6210\u304c\u6301\u7d9a\u7684\u3067\u8272\u7d20\u6c88\u7740\u304c\u6700\u59273\u30f6\u6708\u7d9a\u304f\u3053\u3068\u3001\u7279\u306b\u808c\u30bf\u30a4\u30d7III\u4ee5\u4e0a\u306e\u6fc3\u3044\u808c\u8272\u3067\u9855\u8457\u3067\u3042\u308b\u3053\u3068\u3092\u5b9f\u8a3c\u3002\u8a18\u4e8b\u306eHEV\u306b\u3088\u308b\u76ae\u819a\u30c0\u30e1\u30fc\u30b8\u3068\u8272\u7d20\u6c88\u7740\u30e1\u30ab\u30cb\u30ba\u30e0\u306e\u79d1\u5b66\u7684\u6839\u62e0\u3092\u63d0\u4f9b\u3059\u308b\u57fa\u790e\u6587\u732e\u3002
\r\n\r\n\u30102\u3011Duteil L, Cardot-Leccia N, Queille-Roussel C, et al. Differences in visible light-induced pigmentation according to wavelengths: a clinical and histological study in comparison with UVB exposure. Pigment Cell Melanoma Res. 2014;27(5):822-826. <\/a><\/cite>
\r\n\r\nPMID: 24888214 DOI: 10.1111\/pcmr.12273
\r\n\r\n\u65e5\u672c\u8a9e\u8981\u65e8:<\/strong>\u30d6\u30eb\u30fc\u30e9\u30a4\u30c8(415nm)\u304c\u8272\u7d20\u6c88\u7740\u3092\u8a98\u5c0e\u3057\u3001\u305d\u306e\u52b9\u679c\u304c\u6ce2\u9577\u306b\u3088\u3063\u3066\u7570\u306a\u308b\u3053\u3068\u3092\u81e8\u5e8a\u7684\u30fb\u7d44\u7e54\u5b66\u7684\u306b\u5b9f\u8a3c\u3002\u7279\u306b\u808c\u30bf\u30a4\u30d7III-IV\u306b\u304a\u3044\u3066\u3001\u30d6\u30eb\u30fc\u30e9\u30a4\u30c8\u306b\u3088\u308b\u8272\u7d20\u6c88\u7740\u306fUVB\u3068\u6bd4\u8f03\u3057\u3066\u8457\u3057\u304f\u5f37\u304f\u3001\u6700\u59273\u30f6\u6708\u6301\u7d9a\u3059\u308b\u3053\u3068\u3092\u793a\u3057\u305f\u3002\u4e00\u65b9\u3001\u8d64\u8272\u5149(630nm)\u3067\u306f\u8272\u7d20\u6c88\u7740\u3092\u8a98\u5c0e\u3057\u306a\u304b\u3063\u305f\u3002\u8a18\u4e8b\u306e\u30d6\u30eb\u30fc\u30e9\u30a4\u30c8\u306b\u3088\u308b\u8272\u7d20\u6c88\u7740\u30e1\u30ab\u30cb\u30ba\u30e0\u306e\u76f4\u63a5\u7684\u306a\u79d1\u5b66\u7684\u6839\u62e0\u3092\u63d0\u4f9b\u3059\u308b\u6587\u732e\u3002
\r\n\r\n\u30103\u3011Regazzetti C, Sormani L, Debayle D, et al. Melanocytes sense blue light and regulate pigmentation through Opsin-3. J Invest Dermatol. 2018;138(1):171-178.<\/a><\/cite>
\r\n\r\nPMID: 28842328 DOI: 10.1016\/j.jid.2017.07.833
\r\n\r\n\u65e5\u672c\u8a9e\u8981\u65e8:<\/strong>\u30e1\u30e9\u30ce\u30b5\u30a4\u30c8\u304cOpsin-3(OPN3)\u3092\u4ecb\u3057\u3066\u30d6\u30eb\u30fc\u30e9\u30a4\u30c8(415nm)\u3092\u611f\u77e5\u3057\u3001\u8272\u7d20\u6c88\u7740\u3092\u5236\u5fa1\u3059\u308b\u5206\u5b50\u30e1\u30ab\u30cb\u30ba\u30e0\u3092\u89e3\u660e\u3002\u30d6\u30eb\u30fc\u30e9\u30a4\u30c8\u304cOPN3\u3092\u6d3b\u6027\u5316\u3057\u3001\u30ab\u30eb\u30b7\u30a6\u30e0\u4f9d\u5b58\u6027\u7d4c\u8def\u3092\u4ecb\u3057\u3066CaMKII\u3001CREB\u3001ERK\u3001p38\u3092\u6d3b\u6027\u5316\u3057\u3001MITF\u306e\u30ea\u30f3\u9178\u5316\u3092\u8a98\u5c0e\u3002\u3053\u308c\u306b\u3088\u308a\u30c1\u30ed\u30b7\u30ca\u30fc\u30bc\u3068\u30c9\u30fc\u30d1\u30af\u30ed\u30fc\u30e0\u30c8\u30fc\u30c8\u30e1\u30e9\u30fc\u30bc\u306e\u8907\u5408\u4f53\u5f62\u6210\u304c\u4fc3\u9032\u3055\u308c\u3001\u7279\u306b\u808c\u30bf\u30a4\u30d7III\u4ee5\u4e0a\u3067\u6301\u7d9a\u7684\u306a\u8272\u7d20\u6c88\u7740\u3092\u5f15\u304d\u8d77\u3053\u3059\u3053\u3068\u3092\u5b9f\u8a3c\u3002\u8a18\u4e8b\u306e\u30d6\u30eb\u30fc\u30e9\u30a4\u30c8\u611f\u77e5\u3068\u8272\u7d20\u6c88\u7740\u306e\u5206\u5b50\u30e1\u30ab\u30cb\u30ba\u30e0\u306e\u79d1\u5b66\u7684\u6839\u62e0\u3092\u63d0\u4f9b\u3059\u308b\u91cd\u8981\u6587\u732e\u3002
\r\n\r\n\u30104\u3011Behar-Cohen F, Baillet G, de Ayguavives T, et al. Ultraviolet damage to the eye revisited: eye-sun protection factor (E-SPF\u00ae), a new ultraviolet protection label for eyewear. Clin Ophthalmol. 2014;8:87-104.<\/a><\/cite>
\r\n\r\nPMID: 24379652 DOI: 10.2147\/OPTH.S461
\r\n\r\n\u65e5\u672c\u8a9e\u8981\u65e8:<\/strong>\u773c\u3078\u306eUV\u66dd\u9732\u3068\u30b5\u30f3\u30b0\u30e9\u30b9\u306e\u4fdd\u8b77\u52b9\u679c\u3092\u5305\u62ec\u7684\u306b\u89e3\u8aac\u3002\u30ec\u30f3\u30ba\u306eUV\u900f\u904e\u3060\u3051\u3067\u306a\u304f\u3001\u30ec\u30f3\u30ba\u80cc\u9762\u304b\u3089\u306e\u53cd\u5c04(\u30d0\u30c3\u30af\u30ea\u30d5\u30ec\u30af\u30b7\u30e7\u30f3)\u3082\u773c\u3078\u306eUV\u66dd\u9732\u306b\u5927\u304d\u304f\u5bc4\u4e0e\u3057\u3001\u901a\u5e38\u306e\u53cd\u5c04\u9632\u6b62\u30b3\u30fc\u30c6\u30a3\u30f3\u30b0\u306fUV\u53cd\u5c04\u3092\u5897\u52a0\u3055\u305b\u308b\u3053\u3068\u3092\u5b9f\u8a3c\u3002\u30ec\u30f3\u30ba\u306e\u900f\u904e\u7387\u3068\u53cd\u5c04\u7387\u306e\u4e21\u65b9\u3092\u7d71\u5408\u3057\u305f\u65b0\u3057\u3044\u773c\u7528\u65e5\u713c\u3051\u6b62\u3081\u4fc2\u6570(E-SPF\u00ae)\u3092\u63d0\u5531\u3002\u8a18\u4e8b\u306eUV\u30ab\u30c3\u30c8\u30b5\u30f3\u30b0\u30e9\u30b9\u306e\u4fdd\u8b77\u30e1\u30ab\u30cb\u30ba\u30e0\u3068\u9078\u3073\u65b9\u306e\u79d1\u5b66\u7684\u6839\u62e0\u3092\u63d0\u4f9b\u3059\u308b\u91cd\u8981\u6587\u732e\u3002
\r\n\r\n\u30105\u3011Mann T, Eggers K, Rippke F, Tesch M, Buerger A, Darvin ME, Schanzer S, Meinke MC, Lademann J, Kolbe L. High-energy visible light at ambient doses and intensities induces oxidative stress of skin\u2014Protective effects of the antioxidant and Nrf2 inducer Licochalcone A in vitro and in vivo. Photodermatol Photoimmunol Photomed. 2020;36(2):135-145.<\/a><\/cite>
\r\n\r\nPMID: 31661571 DOI: 10.1111\/phpp.12523
\r\n\r\n\u65e5\u672c\u8a9e\u8981\u65e8:<\/strong>HEV\u5149(400-500nm)\u304c\u65e5\u5e38\u7684\u306a\u7167\u5c04\u91cf(\u6674\u5929\u306e\u590f\u306e\u65e5\u30011\u6642\u9593\u76f8\u5f53\u306e150 J\/cm\u00b2)\u3067\u3082\u6d3b\u6027\u9178\u7d20\u7a2e(ROS)\u3092\u8a98\u5c0e\u3057\u3001\u76ae\u819a\u306e\u9178\u5316\u30b9\u30c8\u30ec\u30b9\u3092\u5f15\u304d\u8d77\u3053\u3059\u3053\u3068\u3092\u5b9f\u8a3c\u3002\u5f93\u6765\u306eUV\u30d5\u30a3\u30eb\u30bf\u30fc(SPF50+)\u3067\u306fHEV\u8a98\u5c0e\u306eROS\u3092\u9632\u3052\u306a\u3044\u304c\u3001\u6297\u9178\u5316\u6210\u5206Licochalcone A(LicA)\u306e\u524d\u51e6\u7406\u306b\u3088\u308a\u975e\u7167\u5c04\u30ec\u30d9\u30eb\u307e\u3067ROS\u751f\u6210\u3092\u6291\u5236\u3067\u304d\u308b\u3053\u3068\u3092\u793a\u3057\u305f\u3002\u8a18\u4e8b\u306eHEV\u306b\u3088\u308b\u9178\u5316\u30b9\u30c8\u30ec\u30b9\u3068\u6297\u9178\u5316\u4fdd\u8b77\u306e\u5fc5\u8981\u6027\u306e\u79d1\u5b66\u7684\u6839\u62e0\u3092\u63d0\u4f9b\u3059\u308b\u91cd\u8981\u6587\u732e\u3002
\r\n\r\n\u30106\u3011Ceylan E, Beder N, Karakaya G, Kalyoncu AF. Wraparound eyeglasses improve symptoms and quality of life in patients with seasonal allergic rhinoconjunctivitis. Int Forum Allergy Rhinol. 2016;6(7):719-724.<\/a><\/cite>
\r\n\r\nPMID: 26919554 DOI: 10.1002\/alr.21735
\r\n\r\n\u65e5\u672c\u8a9e\u8981\u65e8:<\/strong>\u30e9\u30c3\u30d7\u30a2\u30e9\u30a6\u30f3\u30c9\u578b\u30b5\u30f3\u30b0\u30e9\u30b9(\u9854\u3092\u8986\u3046\u30c7\u30b6\u30a4\u30f3)\u304c\u5b63\u7bc0\u6027\u30a2\u30ec\u30eb\u30ae\u30fc\u6027\u9f3b\u7d50\u819c\u708e\u60a3\u8005\u306e\u75c7\u72b6\u3068\u751f\u6d3b\u306e\u8cea\u3092\u6539\u5584\u3059\u308b\u3053\u3068\u3092\u5b9f\u8a3c\u3057\u305f\u7814\u7a76\u300270\u540d\u306e\u60a3\u8005\u3092\u5bfe\u8c61\u3068\u3057\u305f3\u5e74\u9593(2011-2013\u5e74)\u306e\u30e9\u30f3\u30c0\u30e0\u5316\u6bd4\u8f03\u8a66\u9a13\u3067\u3001\u30e9\u30c3\u30d7\u30a2\u30e9\u30a6\u30f3\u30c9\u578b\u30e1\u30ac\u30cd\u3092\u7740\u7528\u3057\u305f\u30b0\u30eb\u30fc\u30d7\u306f\u3001\u85ac\u7269\u6cbb\u7642\u306e\u307f\u306e\u30b0\u30eb\u30fc\u30d7\u3068\u6bd4\u8f03\u3057\u3066\u3001\u75c7\u72b6\u30b9\u30b3\u30a2\u3068RQLQ(\u9f3b\u7d50\u819c\u708eQOL\u8cea\u554f\u7968)\u30b9\u30b3\u30a2\u306e\u6709\u610f\u306a\u6539\u5584\u3092\u793a\u3057\u305f\u3002\u8a18\u4e8b\u306e\u30a2\u30a4\u30b1\u30a2\u30e1\u30ac\u30cd\u306b\u3088\u308b\u82b1\u7c89\u30ab\u30c3\u30c8\u52b9\u679c\u3068\u75c7\u72b6\u6539\u5584\u306e\u79d1\u5b66\u7684\u6839\u62e0\u3092\u63d0\u4f9b\u3059\u308b\u91cd\u8981\u6587\u732e\u3002
\r\n\r\n\u30107\u3011Ozturk AB, Damadoglu E, Karakaya G, Kalyoncu AF. Protective efficacy of sunglasses on the conjunctival symptoms of seasonal rhinitis. Int Arch Allergy Immunol. 2013;162(4):315-319.<\/a><\/cite>
\r\n\r\nPMID: 24039213 DOI: 10.1159\/000353355
\r\n\r\n\u65e5\u672c\u8a9e\u8981\u65e8:<\/strong>\u30b5\u30f3\u30b0\u30e9\u30b9\u304c\u5b63\u7bc0\u6027\u9f3b\u708e\u60a3\u8005\u306e\u7d50\u819c\u75c7\u72b6\u3092\u8efd\u6e1b\u3059\u308b\u52b9\u679c\u3092\u5b9f\u8a3c\u3057\u305f\u7814\u7a76\u300239\u540d\u306e\u60a3\u8005\u3092\u5bfe\u8c61\u3068\u3057\u305f4\u9031\u9593\u306e\u30e9\u30f3\u30c0\u30e0\u5316\u6bd4\u8f03\u8a66\u9a13\u3067\u3001\u65e5\u4e2d\u306b\u30b5\u30f3\u30b0\u30e9\u30b9\u3092\u7740\u7528\u3057\u305f\u30b0\u30eb\u30fc\u30d7\u306f\u3001\u7740\u7528\u3057\u306a\u304b\u3063\u305f\u30b0\u30eb\u30fc\u30d7\u3068\u6bd4\u8f03\u3057\u3066\u773c\u75c7\u72b6\u304c\u6709\u610f\u306b\u6e1b\u5c11(p=0.002)\u3057\u3001\u6297\u30d2\u30b9\u30bf\u30df\u30f3\u85ac\u306e\u4f7f\u7528\u3082\u6709\u610f\u306b\u6e1b\u5c11(p=0.009)\u3057\u305f\u3002\u30b5\u30f3\u30b0\u30e9\u30b9\u306f\u82b1\u7c89\u304b\u3089\u76ee\u3092\u4fdd\u8b77\u3059\u308b\u5b89\u4fa1\u3067\u30b7\u30f3\u30d7\u30eb\u304b\u3064\u52b9\u679c\u7684\u306a\u6cbb\u7642\u6cd5\u3067\u3042\u308b\u3053\u3068\u3092\u793a\u3057\u305f\u3002\u8a18\u4e8b\u306e\u30b5\u30f3\u30b0\u30e9\u30b9\u306b\u3088\u308b\u82b1\u7c89\u9632\u5fa1\u52b9\u679c\u306e\u79d1\u5b66\u7684\u6839\u62e0\u3092\u63d0\u4f9b\u3059\u308b\u6587\u732e\u3002
\r\n\r\n\u30108\u3011Kim SJ, Chae HG, Lee JW, Kang YS. Wearing comfort and perceived heaviness of smart glasses. Hum Factors Ergon Manuf Serv Ind. 2021;31(4):484-497.<\/a><\/cite>
\r\n\r\nDOI: 10.1002\/hfm.20895
\r\n\r\n\u65e5\u672c\u8a9e\u8981\u65e8:<\/strong>\u30b9\u30de\u30fc\u30c8\u30b0\u30e9\u30b9\u306e\u91cd\u91cf\u3068\u88c5\u7740\u5feb\u9069\u6027\u306e\u95a2\u4fc2\u3092\u8abf\u67fb\u3057\u305f\u7814\u7a76\u300278\u540d\u306e\u88ab\u9a13\u8005\u3092\u5bfe\u8c61\u306b\u3001\u97d3\u56fd\u4eba\u306e\u9854\u9762\u30fb\u982d\u90e8\u5bf8\u6cd5\u30c7\u30fc\u30bf\u30d9\u30fc\u30b9\u306b\u57fa\u3065\u3044\u3066\u8a2d\u8a08\u3055\u308c\u305f\u30d7\u30ed\u30c8\u30bf\u30a4\u30d7\u3092\u7528\u3044\u3066\u3001\u88c5\u7740\u5feb\u9069\u6027\u3001\u77e5\u899a\u3055\u308c\u308b\u91cd\u3055\u3001\u611f\u899a\u95be\u5024\u3092\u6e2c\u5b9a\u3002\u30d7\u30ed\u30c8\u30bf\u30a4\u30d7\u306e\u91cd\u91cf\u304c\u5897\u52a0\u3059\u308b\u306b\u3064\u308c\u3066\u77e5\u899a\u3055\u308c\u308b\u91cd\u3055\u3082\u5897\u52a0\u3057\u3001\u77e5\u899a\u3055\u308c\u308b\u91cd\u3055\u3068\u88c5\u7740\u5feb\u9069\u6027\u306e\u9593\u306b\u306f\u5f37\u3044\u8ca0\u306e\u76f8\u95a2(p<.001, r=-0.838)\u304c\u8a8d\u3081\u3089\u308c\u305f\u3002\u56de\u5e30\u5206\u6790\u306b\u3088\u308a\u3001\u91cd\u91cf\u5897\u52a0\u306e\u95be\u5024\u306f39.13g\u3001\u91cd\u91cf\u30d0\u30e9\u30f3\u30b9\u5dee\u306e\u95be\u5024\u306f\u00b114.16g\u3067\u3042\u308b\u3053\u3068\u3092\u793a\u3057\u305f\u3002\u8a18\u4e8b\u306e\u30e1\u30ac\u30cd\u306e\u91cd\u3055\u3068\u5feb\u9069\u6027\u30fb\u75b2\u52b4\u306e\u95a2\u4fc2\u306e\u79d1\u5b66\u7684\u6839\u62e0\u3092\u63d0\u4f9b\u3059\u308b\u6587\u732e\u3002
\r\n\r\n\u30109\u3011Lin JB, Gerratt BW, Bassi CJ, Apte RS. Short-wavelength light-blocking eyeglasses attenuate symptoms of eye fatigue. Invest Ophthalmol Vis Sci. 2017;58(1):442-447. <\/a><\/cite>
\r\n\r\nDOI: 10.1167\/iovs.16-20663
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 <\/p>\n
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