What is nahlsgen

Nahlsgen is
the key ingredient
for nahls Brand

Nahls contains Nahlsgen at the recommended maximum concentration.
Nahlsgen is a revolutionary anti-aging cosmetic ingredient invented at Kyoto University in 2012.
Nahlsgen activates your skin cells and increases collagen and elastin.
Nahlsgen also has been proven as prominent ingredient for skin care based on experimental data and medicine thesis.

Beyond the 30's, skin cells lose vitality and collagen and elastin are reduced. As a result, the skin loses its elasticity and gloss, while wrinkles and sagging skin becomes more conspicuous.
Nahlsgen provides vitality to this skin and creates a firmness and gloss.

Graduate School of Human Life Sciences, Osaka City University × Chemical Laboratory of  Kyoto University

Nahlsgen is a breakthrough aging-care cosmetic ingredient discovered at Kyoto University, co-developed with Osaka City University, and created in 2012 through an industry-academia collaboration.
The unique attribute of Nahlsgen is that it stimulates the innate human power of skin regeneration and thus reduces the effects of skin aging. Nahlsgen promotes the ability to maintain firm and smooth skin.

※Nahlsgen is a registered trademark of nahls Corporation.

Nahlsgen
10 key features

1 More than doubles the source of elasticity, "collagen".

Nahlsgen allows the body to produce:

  • Over twice as much collagen
  • About 1.5 times elastin
  • Approximately 1.3 times higher than HSP47

Basic experiments in our laboratory have shown that Nahlsgen activates dermal fibroblasts and increases dermal collagen, elastin and HSP47.
Collagen, elastin, and HSP47 are proteins of the dermis and they are important ingredients for the firmness and gloss of the skin.

  • Type 1 collagen production

    Nahlsgen increases by 2 to 3 times the amount of "collagen" that keeps the elasticity, firmness and luster of the skin.

  • Elastin production

    Nahlsgen increases the elastic fiber "Elastin" by approximately 1.5 times.

  • HSP47 production

    Nahlsgen increases HSP47, which enhances collagen quality, approximately 1.3 times.

2New facts! Increase hyaluronic acid and HSP70!

It has been found that Nahlsgen increases hyaluronic acid, which keeps the skin moisturized, and HSP (Heat Shock Protein) 70, which works to prevent spots, wrinkles, and sporadic lines.

3Synergistic effect with Vitamin C increases collagen further.

Nahlsgen has been proven to have a synergistic effect when used with Vitamin C.
Using Nahlsgen + Vitamin C together produced more collagen than using each alone.

4Penetrates into the skin deeply and thoroughly; able to be transported to the stratum corneum

Difference in size of each molecule

Nahlsgen is a very small amino-acid derivative with a molecular weight of 331.26 daltons.
Since it is a smaller component than low molecular weight collagen, it penetrates deeply and thoroughly into the stratum corneum.

Changes in  keratin water content due to continuous use of nahlsgen for 4 and 8 weeks

5Maintains the moisture content of the skin and keeps it moisturized

It has been shown that Nahlsgen brings firmness and gloss to the skin by adjusting the natural moisturizing power of the cells themselves.
This is one of the most important points as moisturizing is the basis of anti-aging skin care.

Changes in skin elasticity of Nahlsgen

6Keeps your skin firm

Test results using a lotion containing Nahlsgen for 1 to 3 months in a human monitor test, the skin elasticity was significantly improved compared to the placebo.

Cell protection from UV rays

7Prevents "photoaging", the damage caused by ultraviolet rays

Ultraviolet rays increase the reactive oxygen on skin and thus cause damage. Furthermore, UV kills fibroblasts and degrades collagen and elastin. This is called "photoaging".
Nahlsgen has been proven to reduce UV damage in basic experiments

Changes in the amount of glutathione in human skin cells due to addition of nahlsgen

8Anti-oxidant action supports blemish-free skin care

Nahlsgen has been proved by basic experiments to increase the amount of glutathione in epidermal cells, reducing incidence of blemishing.
Glutathione is a highly antioxidant component of the human body and skin.

Main effects of cosmetic ingredients

9Nine-effects in one ingredient

Nahlsgen can be expected to have nine aging-care effects including collagen production and elastin production.
In addition, since the nahls brand products contain Nahlsgen which always contains vitamin C derivatives, it can be expected to help improve major anti-aging care effects.

10Nahlsgen is a safe anti-aging care cosmetic ingredient.

Nahlsgen is a safe aging-care cosmetic ingredient that is neither irritating or toxic.
Based on the "Guidelines for Safety Evaluation of Cosmetics" test (Japan Cosmetic Industry Association), no toxicity or irritation was observed.
Furthermore, in four additional tests, toxicity to humans or cells was not observed.

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